Results 181 to 190 of about 52,371 (282)

Effects of Hydrocodone Overdose and Ceftriaxone on Astrocytic Glutamate Transporters and Glutamate Receptors, and Associated Signaling in Nucleus Accumbens as well as Locomotor Activity in C57/BL Mice

open access: yesBrain Sciences
Chronic opioid treatments dysregulate the glutamatergic system, inducing a hyperglutamatergic state in mesocorticolimbic brain regions. This study investigated the effects of exposure to hydrocodone overdose on locomotor activity, expression of target ...
Woonyen Wong, Youssef Sari
doaj   +1 more source

GABAB Receptors Mediate Intracellular Calcium Release in Astrocytes of the Prefrontal Cortex

open access: yesEuropean Journal of Neuroscience, Volume 62, Issue 1, July 2025.
We took advantage of GLAST‐promoter driven GCaMP6s expression in astrocytes to study Ca2+ signaling in astrocytes of the young adult prefrontal cortex in response to GABA with confocal Ca2+ imaging. The results show that GABA induces Ca2+ signaling via the stimulation of the metabotropic GABAB receptor in astrocytes.
Jennifer Bostel   +2 more
wiley   +1 more source

Estrogenic regulation of hippocampal inhibitory system across lifespan

open access: yesJournal of Neuroendocrinology, Volume 37, Issue 7, July 2025.
Abstract Estrogens produced in peripheral tissues and locally in the brain are potent neuromodulators. The function of the hippocampus, a brain region essential for episodic memory and spatial navigation, relies on the activity of ensembles of excitatory neurons whose activity is temporally and spatially coordinated by a wide diversity of inhibitory ...
Pablo Méndez   +2 more
wiley   +1 more source

Dual neurotoxic and neuroprotective role of metabotropic glutamate receptor 1 in conditions of trophic deprivation – Possible role as a dependence receptor [PDF]

open access: green, 2008
Sergey Pshenichkin   +5 more
openalex   +1 more source

AMPA receptor and metabotropic glutamate receptor 1 adaptations in the nucleus accumbens core during incubation of methamphetamine craving. [PDF]

open access: yesNeuropsychopharmacology, 2019
Murray CH   +8 more
europepmc   +1 more source

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