Results 41 to 50 of about 112,378 (256)
Does Corticothalamic Feedback Control Cortical Velocity Tuning? [PDF]
, 2001 The thalamus is the major gate to the cortex and its contribution to cortical receptive field properties is well established. Cortical feedback to the thalamus is, in turn, the anatomically dominant input to relay cells, yet its influence on thalamic ...
Hillenbrand, Ulrich, van Hemmen, J. Leo
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Frontiers in Cellular Neuroscience, 2018 Metabotropic glutamate receptors (mGlus) are G Protein coupled-receptors that modulate synaptic transmission and plasticity in the central nervous system.
Simon Bossi +8 more
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Hippocampal neuronal cells that accumulate α-synuclein fragments are more vulnerable to Aβ oligomer toxicity via mGluR5--implications for dementia with Lewy bodies. [PDF]
, 2014 BackgroundIn dementia with Lewy bodies (DLB) abnormal interactions between α-synuclein (α-syn) and beta amyloid (Aβ) result in selective degeneration of neurons in the neocortex, limbic system and striatum.
Cartier, Anna +9 more
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Glutamatergic Mechanisms in Glioblastoma and Tumor-Associated Epilepsy
Cells, 2021 The progression of glioblastomas is associated with a variety of neurological impairments, such as tumor-related epileptic seizures. Seizures are not only a common comorbidity of glioblastoma but often an initial clinical symptom of this cancer entity ...
Falko Lange +2 more
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ASN Neuro, 2009 A number of studies suggest that OLGs (oligodendrocytes), the myelinating cells of the central nervous system, are also a source of trophic molecules, such as neurotrophins that may influence survival of proximate neurons.
Issa P Bagayogo, Cheryl F Dreyfus
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AMPA and Kainate Receptors Each Mediate Excitotoxicity in Oligodendroglial Cultures
Neurobiology of Disease, 1999 Recent studies indicate that oligodendrocytes are vulnerable to excitotoxic insults mediated by glutamate receptors. The present study was carried out to characterize the type of glutamate receptors triggering cell death in optic nerve oligodendrocyte ...
Maria Victoria Sánchez-Gómez +1 more
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L-Glutamate supplementation improves small intestinal architecture and enhances the expressions of jejunal mucosa amino acid receptors and transporters in weaning piglets. [PDF]
PLoS ONE, 2014 L-Glutamate is a major oxidative fuel for the small intestine. However, few studies have demonstrated the effect of L-glutamate on the intestinal architecture and signaling of amino acids in the small intestine.
Meng Lin +7 more
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Glutaminolysis drives membrane trafficking to promote invasiveness of breast cancer cells
Nature Communications, 2017 Glutamine metabolism is well known to support tumour growth. Here the authors show that cancer cells also utilize glutamine to promote invasiveness by converting it to glutamate, which upon secretion activates metabotropic glutamate receptors to ...
Emmanuel Dornier +13 more
doaj +1 more source
Biological Research, 2014 BACKGROUND: The hippocampal CA3 area contains large amounts of vesicular zinc in the mossy fiber terminals which is released during synaptic activity, depending on presynaptic calcium.
Carlos M Matias +3 more
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Mechanism of neuroprotective effect of mGluR4 agonists [PDF]
Research Results in Pharmacology, 2019 Introduction: This review of literature is to demonstrate a role of group III metabotropic glutamate receptors in maintaining the level of extracellular glutamate in ischemic stroke and neurodegenerative diseases.
Natalya V. Avdeeva +4 more
doaj +3 more sources