Results 91 to 100 of about 71,233 (313)
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Inherited retinal dystrophies (IRDs) inherited are visually disabling monogenic diseases with remarkable genetic and phenotypic heterogeneity. Mutations in more than 300 different genes have been identified as disease‐causing. The genetic diagnosis of IRDs has significantly advanced with the integration of Next Generation Sequencing (NGS ...
Gerardo E. Fabian‐Morales +6 more
wiley +1 more source
Enhancing Long-Read-Based Strain-Aware Metagenome Assembly
Frontiers in Genetics, 2022 Microbial communities are usually highly diverse and often involve multiple strains from the participating species due to the rapid evolution of microorganisms.
Xiao Luo +4 more
doaj +1 more source
Explaining microbial population genomics through phage predation [PDF]
, 2009 The remarkable diversity of genes within the pool of prokaryotic genomes belonging to the same species or pan-genome is difficult to reconcile with the widely accepted paradigm which asserts that periodic selection within bacterial populations would ...
Alex Mira +6 more
core +2 more sources
Back to the Future of Soil Metagenomics [PDF]
Frontiers in Microbiology, 2016 JN was funded by a fellowship from the French MENESR.
Yong-Guan Zhu +49 more
openaire +13 more sources
An Update: Enzymatic Synthesis for Industrial Applications
Angewandte Chemie International Edition, EarlyView.Biocatalysis has become a sustainable and cost‐competitive alternative to established chemical synthesis, enabling the enzyme‐based production of not only commodity chemicals but (non‐natural) amino acids, (rare) sugars, as well as synthetic nucleotides.
Thomas Bayer +4 more
wiley +1 more source
Microbiology Spectrum, 2022 The gastrointestinal microbiota members produce α-l-fucosidases that play key roles in mucosal, human milk, and dietary oligosaccharide assimilation. Here, 36 open reading frames (ORFs) coding for putative α-l-fucosidases belonging to glycosyl hydrolase ...
Eva M. Moya-Gonzálvez +7 more
doaj +1 more source
Characteristics of Wetting-Induced Bacteriophage Blooms in Biological Soil Crust. [PDF]
, 2019 Biological soil crusts (biocrusts) are photosynthetic "hot spots" in deserts and cover ∼12% of the Earth's terrestrial surface, and yet they face an uncertain future given expected shifts in rainfall events.
Northen, Trent R +4 more
core +2 more sources
A Bioinformatician's Guide to Metagenomics [PDF]
Microbiology and Molecular Biology Reviews, 2008 SUMMARYAs random shotgun metagenomic projects proliferate and become the dominant source of publicly available sequence data, procedures for the best practices in their execution and analysis become increasingly important. Based on our experience at the Joint Genome Institute, we describe the chain of decisions accompanying a metagenomic project from ...
Kunin, V. +4 more
openaire +4 more sources
Species-Associated Differences in the Below-Ground Microbiomes of Wild and Domesticated Setaria
Frontiers in Plant Science, 2018 The rhizosphere microbiome is known to play a crucial role in promoting plant growth, partly by countering soil-borne phytoparasites and by improving nutrient uptake.
Srinivasa Chaluvadi +1 more
doaj +1 more source
Reviews in Medical Virology, 2007 AbstractCharacterisation of new viruses is often hindered by difficulties in amplifying them in cell culture, limited antigenic/serological cross‐reactivity or the lack of nucleic acid hybridisation to known viral sequences. Numerous molecular methods have been used to genetically characterise new viruses without prior in vitro replication or the use ...
openaire +2 more sources