Results 51 to 60 of about 140,801 (215)
metagenome-atlas/atlas: Toiminnot
, 2021 This is a major update of metagenome-atlas. It was developed for the 3-day course in Finnland, that's also why it has a finish release name. What is new?
Silas Kieser +12 more
core +1 more source
Noncanonical Peloruside A Biosynthesis by an Uncultivated Verrucomicrobiota Symbiont
Angewandte Chemie, EarlyView.Noncanonical biochemistry of the peloruside PKS characterized in this work, comprising double bond generation by a noncanonical tridomain (blue), acetyl‐CoA recycling (orange), and proofreading systems (purple and yellow). The Z‐double bond is installed by TEB1 through O‐acetylation and acetate elimination. The acyl ligase PelB (AL, orange) selectively
Amy E. Fraley +11 more
wiley +2 more sources
Mining virulence genes using metagenomics.
PLoS ONE, 2011 When a bacterial genome is compared to the metagenome of an environment it inhabits, most genes recruit at high sequence identity. In free-living bacteria (for instance marine bacteria compared against the ocean metagenome) certain genomic regions are ...
Pedro Belda-Ferre +3 more
doaj +1 more source
metagenome-atlas/atlas: V2.0.0
, 2019 <p>ATLAS - Three commands to start analysing your metagenome data</p ...
Silas Kieser, Joe Brown
core +1 more source
metagenome-atlas/atlas: Use parquet and pyfastx to handle large gene catalogs
, 2022 What's Changed Make atlas handle large gene catalogs using parquet and pyfastx (Fix #515) parquet files can be opened in python with import pandas as pd coverage = pd.read_parquet("working_dir/Genecatalog/counts/median_coverage.parquet") coverage ...
Silas Kieser +15 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2018 <p>This is linked to GitHub repository <a href="https://github.com/rpetit3/anthrax-metagenome-study">rpetit3/anthrax-metagenome-study</a>.</p ...
Robert A. Petit III (8211633) +1 more
core +2 more sources
Nature CommunicationsUrinary tract infections (UTIs) affect 405 million people worldwide. Current diagnostics rely on cultures, which can take 2 to 4 days. This study evaluates eleven culture-independent methods for sample preparation from 78 complicated UTI patients ...
Anurag Basavaraj Bellankimath +9 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo +14 more
wiley +1 more source