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Application of metagenomic next-generation sequencing in suspected intraocular infections
European Journal of Ophthalmology, 2022Purpose To evaluate the efficacy of metagenomic next-generation sequencing (mNGS) and to explore its value in the diagnosis of intraocular infection. Methods A retrospective case-series study of patients with suspected intraocular infection was performed. Intraocular fluid samples were collected from all the patients and sent for mNGS.
Zhuyun Qian +8 more
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Metagenomic next-generation sequencing for the diagnosis of neurobrucellosis
Future MicrobiologyObjective: This study investigates the application of metagenomic next-generation sequencing (mNGS) in the diagnosis of neurobrucellosis (NB). Methods: We retrospectively analyzed patients diagnosed with NB who underwent cerebrospinal fluid (CSF) mNGS testing in Xijing Hospital from 2015 to 2021. Results: Among the 20 individuals included in the study,
Wen Li +7 more
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Metagenomic next-generation sequencing clinches diagnosis of leishmaniasis
The Lancet, 2021Chong, Wang +3 more
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Metagenome assembly through clustering of next-generation sequencing data using protein sequences
Journal of Microbiological Methods, 2015The study of environmental microbial communities, called metagenomics, has gained a lot of attention because of the recent advances in next-generation sequencing (NGS) technologies. Microbes play a critical role in changing their environments, and the mode of their effect can be solved by investigating metagenomes.
Mikang, Sim, Jaebum, Kim
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Application of Metagenomic Next-Generation Sequencing
Background: Metagenomic high-throughput sequencing (mNGS) represents a powerful tool for detecting nucleic acids from various pathogens, such as bacteria, fungi, viruses and parasites, in clinical samples. Despite its extensively employed in the pathogen diagnosis for various infectious diseases, its application in diagnosing stroke-related infection ...openaire +1 more source
Diagnosis of Mycobacterium marinum Infection by Metagenomic next-generation sequencing
Clinical LaboratoryIn December 2023, our hospital confirmed a case of finger infection with Mycobacterium marinum. The patient sought medical attention at our hospital due to a hard scratch on her left middle finger, which was red, swollen, and ulcerated for one month.A lesion of approximately 1.5 cm x 2 cm in the patient's left middle finger, surrounded by redness and ...
Yan, Zhong, Yun, Xing
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Clinical applications of metagenomics next-generation sequencing in infectious diseases
Journal of Zhejiang University-SCIENCE BInfectious diseases are a great threat to human health. Rapid and accurate detection of pathogens is important in the diagnosis and treatment of infectious diseases. Metagenomics next-generation sequencing (mNGS) is an unbiased and comprehensive approach for detecting all RNA and DNA in a sample.
Ying Liu, Yongjun Ma
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Next-Generation Sequencing Boosts Clinical Metagenomics
Genetic Engineering & Biotechnology News, 2022openaire +1 more source
METAGENOMIC NEXT-GENERATION SEQUENCING (MNGS) FOR PATHOGENS IDENTIFICATION
Metagenomic next-generation sequencing (mNGS) represents approach in a identifying significantly enhancing transformative pathogens, diagnostic capabilities in clinical microbiology. This technology allows for the comprehensive analysis of genetic material from diverse microbial communities without prior knowledge of specific ...Azura Mohd Noor +2 more
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Treatment of muscle‐invasive and advanced bladder cancer in 2020
Ca-A Cancer Journal for Clinicians, 2020Vaibhav G Patel +2 more
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