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Metagenomic next-generation sequencing for the diagnosis of neurobrucellosis
Future MicrobiologyObjective: This study investigates the application of metagenomic next-generation sequencing (mNGS) in the diagnosis of neurobrucellosis (NB). Methods: We retrospectively analyzed patients diagnosed with NB who underwent cerebrospinal fluid (CSF) mNGS testing in Xijing Hospital from 2015 to 2021. Results: Among the 20 individuals included in the study,
Wen Li +7 more
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Clinical Application of Metagenomic Next-Generation Sequencing in Sepsis Patients With Early Antibiotic Treatment [PDF]
Infection and Drug ResistanceYongru Chen,1 Chongyue Chen,1 Wei Chen,2,3 Wei Gai,4 Yafeng Zheng,4 Yuxin Guo,4 Zhaoning Wang,1 Yongsong Chen,1 Zhiming Cai1,5,6 1The First Affiliated Hospital of Shantou University, Shantou, Guangdong, People’s Republic of China; 2Department of Urology,
Zhaoning Wang +2 more
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Metagenomic Next-Generation Sequencing of Viruses Infecting Grapevines
2015Next-generation sequencing (NGS) technologies, for the first time, provide a truly "complete" representation of the viral (and other) pathogens present in a host organism. This is achieved in an unbiased way, and without any prior biological or molecular knowledge of these pathogen(s).
Johan T, Burger, Hans J, Maree
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Application of metagenomic next-generation sequencing in suspected intraocular infections
European Journal of Ophthalmology, 2022Purpose To evaluate the efficacy of metagenomic next-generation sequencing (mNGS) and to explore its value in the diagnosis of intraocular infection. Methods A retrospective case-series study of patients with suspected intraocular ...
Zhuyun Qian +8 more
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Exploring Metagenomes Using Next-Generation Sequencing
2017Metagenomics or community genomics refers to the study of genomic DNA of any culture-independent analysis of microbial communities. Non-culturable microbial groups represent the huge majority of global microorganisms. Microbial populations present in every biological niche even humans body carry 10 times more bacterial cells and 100 times more ...
Jalpa R. Thakkar +2 more
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Targeted Metagenomics Using Next-Generation Sequencing Methods
Metagenomics allows the discovery of the full diversity of all microbes present in a given niche. The technique is very powerful and has allowed very significant advances delineating the role of the microbiome in several disciplines including health, agriculture, ecology, industry, etc.B S, Yugandhar Reddy +2 more
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METAGENOMIC NEXT-GENERATION SEQUENCING (MNGS) FOR PATHOGENS IDENTIFICATION
Metagenomic next-generation sequencing (mNGS) represents approach in a identifying significantly enhancing transformative pathogens, diagnostic capabilities in clinical microbiology. This technology allows for the comprehensive analysis of genetic material from diverse microbial communities without prior knowledge of specific ...Azura Mohd Noor +2 more
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Application of Metagenomic Next-Generation Sequencing
Background: Metagenomic high-throughput sequencing (mNGS) represents a powerful tool for detecting nucleic acids from various pathogens, such as bacteria, fungi, viruses and parasites, in clinical samples. Despite its extensively employed in the pathogen diagnosis for various infectious diseases, its application in diagnosing stroke-related infection ...openaire +1 more source
pathogen next-generation metagenomics sequencing
Pathogens next-generation metagenomics sequencing data from wound swabs or tissues in wound infection patients.openaire +1 more source
Diagnosis of Mycobacterium marinum Infection by Metagenomic next-generation sequencing
Clinical LaboratoryIn December 2023, our hospital confirmed a case of finger infection with Mycobacterium marinum. The patient sought medical attention at our hospital due to a hard scratch on her left middle finger, which was red, swollen, and ulcerated for one month.A lesion of approximately 1.5 cm x 2 cm in the patient's left middle finger, surrounded by redness and ...
Yan, Zhong, Yun, Xing
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