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Neurocysticercosis: diagnosis via metagenomic next-generation sequencing

Practical Neurology, 2023
A 68-year-old Brazilian woman had 3 months of progressive fatigue, difficulty walking and 18 kg weight loss. On examination, there was gait apraxia and executive dysfunction. MR scan of brain showed communicating hydrocephalus and a cerebrospinal fluid showed 105 white cells/µL (≤5), predominantly lymphocytes, protein of 1.35 g/L (0.15–0.45) and the ...
Denison Alves, Pedrosa   +6 more
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METAGENOMIC NEXT-GENERATION SEQUENCING DETECTS PATHOGENS IN ENDOPHTHALMITIS PATIENTS

Retina, 2022
Purpose: To investigate the utility of metagenomic next-generation sequencing (mNGS) in identifying the pathogens in endophthalmitis. Methods: In this prospective study, 36 cases of endophthalmitis were recruited. All patients received surgical treatment and intraocular drug lavage.
Junfeng, Zhu   +9 more
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Adenovirus metagenomic next-generation sequencing

2023
We detected the adenovirus infection in nasopharyngeal swab samples from patients with respiratory tract infection. mNGS was performed on NextSeq 550 and GenoLab M sequencing platforms to study viral phylogenetics and recombination.
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Metagenomic Next-Generation Sequencing in Clinical Microbiology

Clinical Microbiology Newsletter, 2020
Abstract Identification of causative pathogens in infectious disease is a critical component of health care, as infectious diseases continue to be a leading cause of mortality and morbidity worldwide. In addition, the detection of drug resistance by traditional and novel antimicrobial susceptibility testing methods is becoming ever more important as ...
George S. Watts, Bonnie L. Hurwitz
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