Results 251 to 260 of about 4,663,034 (296)

Case Report: Cervical lymphadenitis resulting from <i>Pseudomonas aeruginosa</i> diagnosed by metagenomic next-generation sequencing. [PDF]

Front Pediatr
Gao L, Wen Y, Jing X.
europepmc   +1 more source

Diagnostic Value of Metagenomic Next-Generation Sequencing for Suspected Native Spinal Brucella Infection: A Multicenter Study. [PDF]

Neurospine
Li Z, Zhang Q, Wang H, Zhang Z, Liu J, Li L, Lin Y, Wang Y, Yin C, Wang W, Shen F, Han Z, Hao S, Cong P, Tian T, Liu Q, Chen X, Zhan H, Peng T, Yu X, Pu X, Lian X, Wang T.   +22 more
europepmc   +1 more source

Metagenomic Next-Generation Sequencing for Brain Abscess: Improved Pathogen Detection, Targeted Antimicrobial Therapy, and Association with Fewer Surgical Interventions. [PDF]

Infect Drug Resist
Li X, Fan M, Yue J, Xie J, Zhang Y, Lu X, Liu L, Li X, Huang Y.   +8 more
europepmc   +1 more source

Influence of Ongoing Antibiotic Therapy on the Detection of Pathogenic Microorganisms Using Metagenomic Next-Generation Sequencing and Blood Culture in ICU Patients. [PDF]

J Clin Med
Schroeder TH, Eliwi Alsaffan M, Stäudle H, Dervishi A.   +3 more
europepmc   +1 more source

Clinical Metagenomic Next-Generation Sequencing for Pathogen Detection [PDF]

Annual Review of Pathology: Mechanisms of Disease, 2019
Nearly all infectious agents contain DNA or RNA genomes, making sequencing an attractive approach for pathogen detection. The cost of high-throughput or next-generation sequencing has been reduced by several orders of magnitude since its advent in 2004, and it has emerged as an enabling technological platform for the detection and taxonomic ...
Wei Gu, Steve Miller, Charles Chiu
exaly   +7 more sources

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Neurocysticercosis: diagnosis via metagenomic next-generation sequencing

Practical Neurology, 2023
A 68-year-old Brazilian woman had 3 months of progressive fatigue, difficulty walking and 18 kg weight loss. On examination, there was gait apraxia and executive dysfunction. MR scan of brain showed communicating hydrocephalus and a cerebrospinal fluid showed 105 white cells/µL (≤5), predominantly lymphocytes, protein of 1.35 g/L (0.15–0.45) and the ...
Denison Alves, Pedrosa, Gustavo, Bruniera Peres Fernandes, Luís, Filipe de Souza Godoy, André, C Felício, João Rebello, Pinho, André, Mário Doi, René, de Araújo Gleizer   +6 more
openaire   +2 more sources

Metagenomics Using Next-Generation Sequencing

2014
Traditionally, microbial genome sequencing has been restricted to the small number of species that can be grown in pure culture. The progressive development of culture-independent methods over the last 15 years now allows researchers to sequence microbial communities directly from environmental samples.
Bragg,Lauren, Tyson, Gene W.
openaire   +5 more sources

METAGENOMIC NEXT-GENERATION SEQUENCING DETECTS PATHOGENS IN ENDOPHTHALMITIS PATIENTS

Retina, 2022
Purpose: To investigate the utility of metagenomic next-generation sequencing (mNGS) in identifying the pathogens in endophthalmitis. Methods: In this prospective study, 36 cases of endophthalmitis were recruited. All patients received surgical treatment and intraocular drug lavage.
Junfeng, Zhu, Honghe, Xia, Ruqing, Tang, Tsz Kin, Ng, Fen, Yao, Xulong, Liao, Qi, Zhang, Xixuan, Ke, Tingkun, Shi, Haoyu, Chen   +9 more
openaire   +2 more sources

Adenovirus metagenomic next-generation sequencing

2023
We detected the adenovirus infection in nasopharyngeal swab samples from patients with respiratory tract infection. mNGS was performed on NextSeq 550 and GenoLab M sequencing platforms to study viral phylogenetics and recombination.
openaire   +1 more source