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Application of metagenomic next-generation sequencing in suspected intraocular infections
European Journal of Ophthalmology, 2022Purpose To evaluate the efficacy of metagenomic next-generation sequencing (mNGS) and to explore its value in the diagnosis of intraocular infection. Methods A retrospective case-series study of patients with suspected intraocular ...
Zhuyun Qian +8 more
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METAGENOMIC NEXT-GENERATION SEQUENCING DETECTS PATHOGENS IN ENDOPHTHALMITIS PATIENTS
Retina, 2022Purpose: To investigate the utility of metagenomic next-generation sequencing (mNGS) in identifying the pathogens in endophthalmitis. Methods: In this prospective study, 36 cases of endophthalmitis were recruited. All patients received surgical treatment and intraocular drug lavage.
Junfeng, Zhu +9 more
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Exploring Metagenomes Using Next-Generation Sequencing
2017Metagenomics or community genomics refers to the study of genomic DNA of any culture-independent analysis of microbial communities. Non-culturable microbial groups represent the huge majority of global microorganisms. Microbial populations present in every biological niche even humans body carry 10 times more bacterial cells and 100 times more ...
Jalpa R. Thakkar +2 more
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METAGENOMIC NEXT-GENERATION SEQUENCING (MNGS) FOR PATHOGENS IDENTIFICATION
Metagenomic next-generation sequencing (mNGS) represents approach in a identifying significantly enhancing transformative pathogens, diagnostic capabilities in clinical microbiology. This technology allows for the comprehensive analysis of genetic material from diverse microbial communities without prior knowledge of specific ...Azura Mohd Noor +2 more
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Application of Metagenomic Next-Generation Sequencing
Background: Metagenomic high-throughput sequencing (mNGS) represents a powerful tool for detecting nucleic acids from various pathogens, such as bacteria, fungi, viruses and parasites, in clinical samples. Despite its extensively employed in the pathogen diagnosis for various infectious diseases, its application in diagnosing stroke-related infection ...openaire +1 more source
Diagnosis of Mycobacterium marinum Infection by Metagenomic next-generation sequencing
Clinical LaboratoryIn December 2023, our hospital confirmed a case of finger infection with Mycobacterium marinum. The patient sought medical attention at our hospital due to a hard scratch on her left middle finger, which was red, swollen, and ulcerated for one month.A lesion of approximately 1.5 cm x 2 cm in the patient's left middle finger, surrounded by redness and ...
Yan, Zhong, Yun, Xing
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pathogen next-generation metagenomics sequencing
Pathogens next-generation metagenomics sequencing data from wound swabs or tissues in wound infection patients.openaire +1 more source
Metagenomic next-generation sequencing clinches diagnosis of leishmaniasis
The Lancet, 2021Chong, Wang +3 more
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Clinical applications of metagenomics next-generation sequencing in infectious diseases
Journal of Zhejiang University-SCIENCE BInfectious diseases are a great threat to human health. Rapid and accurate detection of pathogens is important in the diagnosis and treatment of infectious diseases. Metagenomics next-generation sequencing (mNGS) is an unbiased and comprehensive approach for detecting all RNA and DNA in a sample.
Ying Liu, Yongjun Ma
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The real-life performance of metagenomic next-generation sequencing in sepsis
Journal of Infection, 2022Mei, Yin +6 more
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