Results 221 to 230 of about 58,932 (285)

Clinical value of metagenomic next-generation sequencing in diagnosis of Coxiella burnetii infection. [PDF]

BMC Infect Dis
Luo Y, Zhao C, Chen H, Lin Z, Xia J, Liu X, Li X.   +6 more
europepmc   +1 more source

Synergistic engineering of Casδ nuclease for robust genome editing

Journal of Integrative Plant Biology, EarlyView.
A hierarchical engineering strategy was used to enhance the editing activity of Casδ, yielding an optimized variant termed enCasδ. This variant enables robust genome editing in animal cells and plants, with overall editing performance comparable to that of SpCas9 and other Cas12 nucleases.
Fanghui Ge, Chenchen Peng, Yang Du, Ying Chen, Zilong Zhao, Meixia Yu, Huairu Feng, Yuyang Xie, Siwei Sun, Shengnan Liu, Beibei Xin, Haiming Zhao, Sen Wu, Chao Bian, Zhijia Yang, Jinsheng Lai, Jian Chen   +16 more
wiley   +1 more source

Solving the diagnostic dilemma in bone infections: metagenomic next generation sequencing enhances pathogen identification accuracy. [PDF]

Front Med (Lausanne)
Xiao J, Pu C, Zhou X, Zhang X, Zhang S, Yang P, Zhang Y, Xiong L.   +7 more
europepmc   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Family psittacosis cluster diagnosed by metagenomic next-generation sequencing in Hangzhou City, Eastern China: A case series. [PDF]

Medicine (Baltimore)
Sun Z, Xu K, Huo L, Zhang X, Chen B.
europepmc   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Diagnostic value of metagenomic next-generation sequencing in patients with febrile lung cancer with negative conventional microbiological tests and without neutropenia. [PDF]

Front Cell Infect Microbiol
Wang C, Min M, Dai Z, Wang G, Wang Y, Hu T, Ma Y, Zhang S, Wu C, Zhou R.   +9 more
europepmc   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Application Value of Metagenomic Next-Generation Sequencing Using Bronchoalveolar Lavage Fluid and Blood Samples in Patients with Severe Pneumonia Complicated with Bloodstream Infection. [PDF]

Pol J Microbiol
Liu F, Xie F, Zhong Q, Lin X, Yang Q, Li Y, Huang C, Huang Q, Xu L, Zhong J.   +9 more
europepmc   +1 more source

Peri‐Implantitis and Periodontitis: Biological Convergence, Contextual Divergence

Journal of Periodontal Research, EarlyView.
Periodontal and peri‐implant tissues differ and coincide in many aspects, from the clinical and radiological perspective, including histology, microbiology, and molecular markers. Thus, health and disease may also follow different and similar routes.
Pablo Galindo‐Moreno, Pablo Galindo‐Fernandez, Allinson Olaechea, Francisco O'Valle, Abdusalam E. Alrmali, Hom‐Lay Wang, Miguel Padial‐Molina   +6 more
wiley   +1 more source