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Adenovirus metagenomic next-generation sequencing
2023We detected the adenovirus infection in nasopharyngeal swab samples from patients with respiratory tract infection. mNGS was performed on NextSeq 550 and GenoLab M sequencing platforms to study viral phylogenetics and recombination.
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Metagenomic Next-Generation Sequencing in Clinical Microbiology
Clinical Microbiology Newsletter, 2020Abstract Identification of causative pathogens in infectious disease is a critical component of health care, as infectious diseases continue to be a leading cause of mortality and morbidity worldwide. In addition, the detection of drug resistance by traditional and novel antimicrobial susceptibility testing methods is becoming ever more important as ...
George S. Watts, Bonnie L. Hurwitz
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Metagenomic next-generation sequencing for the diagnosis of neurobrucellosis
Future MicrobiologyObjective: This study investigates the application of metagenomic next-generation sequencing (mNGS) in the diagnosis of neurobrucellosis (NB). Methods: We retrospectively analyzed patients diagnosed with NB who underwent cerebrospinal fluid (CSF) mNGS testing in Xijing Hospital from 2015 to 2021. Results: Among the 20 individuals included in the study,
Wen Li +7 more
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Metagenomic Next-Generation Sequencing of Viruses Infecting Grapevines
2015Next-generation sequencing (NGS) technologies, for the first time, provide a truly "complete" representation of the viral (and other) pathogens present in a host organism. This is achieved in an unbiased way, and without any prior biological or molecular knowledge of these pathogen(s).
Johan T, Burger, Hans J, Maree
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Application of metagenomic next-generation sequencing in suspected intraocular infections
European Journal of Ophthalmology, 2022Purpose To evaluate the efficacy of metagenomic next-generation sequencing (mNGS) and to explore its value in the diagnosis of intraocular infection. Methods A retrospective case-series study of patients with suspected intraocular ...
Zhuyun Qian +8 more
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Exploring Metagenomes Using Next-Generation Sequencing
2017Metagenomics or community genomics refers to the study of genomic DNA of any culture-independent analysis of microbial communities. Non-culturable microbial groups represent the huge majority of global microorganisms. Microbial populations present in every biological niche even humans body carry 10 times more bacterial cells and 100 times more ...
Jalpa R. Thakkar +2 more
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METAGENOMIC NEXT-GENERATION SEQUENCING (MNGS) FOR PATHOGENS IDENTIFICATION
Metagenomic next-generation sequencing (mNGS) represents approach in a identifying significantly enhancing transformative pathogens, diagnostic capabilities in clinical microbiology. This technology allows for the comprehensive analysis of genetic material from diverse microbial communities without prior knowledge of specific ...Azura Mohd Noor +2 more
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Application of Metagenomic Next-Generation Sequencing
Background: Metagenomic high-throughput sequencing (mNGS) represents a powerful tool for detecting nucleic acids from various pathogens, such as bacteria, fungi, viruses and parasites, in clinical samples. Despite its extensively employed in the pathogen diagnosis for various infectious diseases, its application in diagnosing stroke-related infection ...openaire +1 more source
pathogen next-generation metagenomics sequencing
Pathogens next-generation metagenomics sequencing data from wound swabs or tissues in wound infection patients.openaire +1 more source
Metagenomic next-generation sequencing clinches diagnosis of leishmaniasis
The Lancet, 2021Chong, Wang +3 more
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