Results 221 to 230 of about 4,937,404 (296)

Cross‐Platform Concordance Between Metagenomic and Targeted DNA Sequencing for Diagnosing Polymicrobial Infections in an Immunosuppressed Patient: A Case Report

Medicine Advances, EarlyView.
An immunosuppressed 40‐year‐old man developed rapidly progressive polymicrobial pneumonia caused by Pneumocystis jirovecii and carbapenem‐resistant Klebsiella pneumoniae. Three metagenomic next‐generation sequencing (mNGS) and targeted next‐generation sequencing (tNGS) workflows with different assay designs and technical parameters consistently ...
Mengxia Wang, Jielun Wen, Liyue Sun
wiley   +1 more source

Enterococcus faecium pneumonia diagnosed by metagenomic next-generation sequencing in a patient with chronic obstructive pulmonary disease. [PDF]

IDCases
Li L, Wang D, Huang C.
europepmc   +1 more source

Toxoplasma gondii Infection After Kidney Transplantation: A Case Report and Literature Review

Organ Medicine, EarlyView.
Toxoplasma gondii infection after kidney transplantation is rare and presents with nonspecific clinical manifestations; however, the associated mortality rate is high. We discuss the relevant literature, clinical manifestations, therapeutic regimens, and prognoses of post‐transplantation toxoplasmosis.
Peng Zhang, Xingqiang Lai, Rongxin Chen, Li Li, Jiali Fang, Guanghui Li, Junjie Ma, Luhao Liu, Zheng Chen   +8 more
wiley   +1 more source

Geometric Intuition Enables Resource‐Efficient Screening for β‐Barrel‐Like Folds in Viral Structural Dark Matter

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Predicted protein structures now enable fold discovery beyond the reach of sequence homology, but scalable and interpretable methods remain limited. We present Cooper‐Beta, a resource‐efficient, chain‐resolved framework for detecting β‐barrel‐like folds from strand connectivity.
Shuyu Zhong, Yuying Jiang
wiley   +1 more source

When metagenomic next-generation sequencing detects <i>Nocardia</i>: from clinical interpretation to immune-based clinical management. [PDF]

Front Cell Infect Microbiol
Li P, Yang X, Chen Y, Wang L, Cui Q, Wu Z, Cao F.   +6 more
europepmc   +1 more source

Breaking Alzheimer's Disease Barrier: The Role of Xanthoceras sorbifolia Bunge Oil in Gut‐Brain Axis and TLR4/Myd88/MAPK Pathway Inhibition

Phytotherapy Research, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with cognitive decline and neuroinflammation. Xanthoceras sorbifolia Bunge oil (XSBO), a woody plant oil rich in bioactive fatty acids, has shown potential health benefits.
Lijing Du, Shikai Yan, Xiaopeng Ren, Syed Shams ul Hassan, Yuanfang Sun, Yu Gan, Xue Xiao, Shasha Li, Huizi Jin   +8 more
wiley   +1 more source

Copy number variation analysis of cerebrospinal fluid metagenomic next-generation sequencing data in assisting the diagnosis of pediatric brain tumors. [PDF]

Pediatr Investig
Ren C, Zhuo X, Yang X, Yao X, Gong S, Xiong H, Fang F, Zhang W.   +7 more
europepmc   +1 more source

Photocatalytic and Biotechnological Strategies for Remediation of Persistent Organic Pollutants: Mechanisms, Toxicity, and Antimicrobial Perspectives

Environmental Toxicology, EarlyView.
ABSTRACT Persistent organic pollutants (POPs) pose significant ecological and human health risks due to their persistence, bioaccumulation, toxicity, and global distribution. Conventional remediation methods are often inadequate for achieving complete mineralization, demonstrating the need for advanced and substantial approaches.
Viola O. Okechukwu, Patrick B. Njobeh, Jonathan O. Okonkwo   +2 more
wiley   +1 more source

Integrating metagenomic next-generation sequencing into a multimodal diagnostic framework for spinal infection: enhancing etiological identification and clinical prediction. [PDF]

Front Cell Infect Microbiol
Liang H, Qin H, Chen J, Qin C, Li X, Wang Q, Luo G, Chen Y.   +7 more
europepmc   +1 more source