Diagnostic value of metagenomic next-generation sequencing in deep neck space infections: a retrospective study of 32 patients. [PDF]
Wang Z, Yang H, Liu J, Li X.
europepmc +1 more source
ABSTRACT Afforestation is widely advocated for boosting carbon (C) sequestration. However, the stability of soil C pools in economically and culturally significant mulberry plantations remains poorly understood. The soil organic C (SOC) contents in different aggregates and the oxidizable OC fractions were measured.
Zi Yang +8 more
wiley +1 more source
Emerging role of metagenomic next-generation sequencing in infectious disease diagnostics: Clinical integration and future directions. [PDF]
Fang T +8 more
europepmc +1 more source
Mixed Litter Decomposition Drives Functional Gene Rearrangement in the Microbial Carbon Cycle
ABSTRACT Understanding how mixed‐species litter decomposition regulates microbial communities and carbon cycling is vital for guiding ecosystem restoration and climate change mitigation, as it is a key process for nutrient cycling and carbon sequestration. A 15‐month field experiment compared single‐species (Pinus sylvestris var.
Jiaying Liu +6 more
wiley +1 more source
Impact of Metagenomic Next-Generation Sequencing on Antibiotic Management in Pediatric Patients. [PDF]
Gonzalez A +3 more
europepmc +1 more source
ABSTRACT Livestock manure is a valuable agricultural resource but may introduce antibiotic residues and antibiotic resistance genes (ARGs) into the environment. This review critically evaluates the fate of antibiotics and ARGs during manure composting and identifies the principal factors controlling their attenuation.
Magdalena Urbaniak
wiley +1 more source
The clinical application of metagenomic next-generation sequencing for invasive pulmonary aspergillosis in neutropenic patients: a multicenter retrospective study in the ICU. [PDF]
Tang J +12 more
europepmc +1 more source
Mapping Causal Biology: Mendelian Randomization in the Era of Big Data
Mendelian randomization (MR) leverages genetic variants to mitigate confounding biases in causal inference. This review systematically maps MR's methodological evolution, highlights its expanding applications in epidemiology and drug target validation, and outlines future directions for overcoming current biases through dynamic, multi‐omics, and cross ...
Xuanlu Shen +10 more
wiley +1 more source
Clinical impact of plasma cell-free DNA metagenomic next-generation sequencing testing in neonatal and infant populations. [PDF]
Pithia N +4 more
europepmc +1 more source
This multi‐omics study identified genetic loci, gut microbiota, blood metabolites, and gray matter volumes of orbitofrontal cortex and cerebellum that were potentially relevant to alerting in healthy Chinese adults. Subsequent two‐step one‐sample Mendelian randomization further revealed a serial mediation pathway: Bacteroides intestinalis influences ...
Hongru Li +8 more
wiley +1 more source

