Metagenomic next-generation sequencing improves diagnosis of <i>Talaromyces marneffei</i> and mixed infections in HIV/AIDS patients: a retrospective study. [PDF]
Li X +10 more
europepmc +1 more source
We assessed whether the maternal perinatal gut microbiome and serum SCFA and cord blood SCFA differ between traditional farming and urban dyads. Women following a farming lifestyle had increased microbial diversity, several differentially abundant bacterial species and functional pathways, and increased circulating SCFA. Overall maternal gut microbiome
Erin C. Davis +7 more
wiley +1 more source
Meta-Analysis of the Application Value of Metagenomic Next-Generation Sequencing Technology in the Diagnosis of Infectious Diseases of the Spine. [PDF]
Cai X +8 more
europepmc +1 more source
Shotgun Metagenomics Reveals Skin Microbiome Composition and Function in Infant Atopic Disease
Deep shotgun metagenomics profiled > 1000 infant skin swabs in the VITALITY cohort. Distinct skin microbiome signatures separated AD alone from AD with allergic co‐occurrence. Early Staphylococcus enrichment preceded later AD with allergic co‐occurrence. FLG mutations and strain‐level analyses revealed host and microbial features linked to AD.
Zeyang Shen +135 more
wiley +1 more source
Metagenomic next-generation sequencing: a game-changer in the diagnosis of unique intraocular infections. [PDF]
Habot-Wilner Z +11 more
europepmc +1 more source
Dietary Habits and Atopic Dermatitis Significantly Influence the Fecal Microbiome
Atopic dermatitis, dietary habits, sex, and BMI significantly influenced the fecal microbiome composition. On the species level, Faecalibacterium taiwanense was more abundant in atopic dermatitis, and Vescimonas sp000435555 was more abundant in the control population. On the genus level, CAG‐302 (NCBI: Clostridium) was more abundant in controls.
Danielle Fehr +14 more
wiley +1 more source
Integrative analysis of pathogen detection, antimicrobial resistance, virulence, and host response in severe infections using metagenomic next-generation sequencing. [PDF]
Chen XG +8 more
europepmc +1 more source
Review Article: The Impact of the Gut Microbiome on Ulcerative Colitis Pharmacotherapy
The gut microbiome modulates ulcerative colitis pharmacotherapy through microbial drug metabolism, immune regulation and altered drug bioavailability. Microbial composition influences response to aminosalicylates, corticosteroids, immunomodulators, biologics and small molecules, while microbiome‐targeted therapies show emerging promise.
Kate Collins +6 more
wiley +1 more source
Clinical application of metagenomic next-generation sequencing in the diagnosis of severe pneumonia pathogens. [PDF]
Huang R +9 more
europepmc +1 more source
A case of infective endocarditis caused by <i>Streptococcus gordonii</i> complicated with bacterial meningitis and cerebral infarction -- Application of metagenomic next-generation sequencing (mNGS). [PDF]
Ye J, Ye L, Sun W, Xie S, Lai Z.
europepmc +1 more source

