Results 201 to 210 of about 58,932 (285)

Diagnostic utility of metagenomic next-generation sequencing for tissue in patients with suspected infectious diseases. [PDF]

Front Cell Infect Microbiol
Liu Y, Tan Y, Xia F, Wu S, Zou S, Chen Q, Liu J, Song S, Du Q, Guo W, Liang K.   +10 more
europepmc   +1 more source

Bringing Gene Therapy Into Real World Clinical Practice

Haemophilia, EarlyView.
ABSTRACT Introduction Adeno‐associated virus (AAV)‐based gene therapy for haemophilia has shifted therapeutic paradigms by enabling hepatic gene transfer, restoring endogenous clotting factor expression, and reducing reliance on conventional prophylactic treatments. Two products, valoctocogene roxaparvovec (haemophilia A) and etranacogene dezaparvovec (
Wolfgang Miesbach, Pratima Chowdary, Margareth C. Ozelo   +2 more
wiley   +1 more source

Optimizing metagenomic next-generation sequencing in CNS infections: a diagnostic model based on CSF parameters. [PDF]

Front Cell Infect Microbiol
Cao XG, Zhu XF, Ni JX, Meng HD, Huang CJ.   +4 more
europepmc   +1 more source

Diet breadth shapes gut microbiota in the invasive hornet Vespa velutina

Insect Conservation and Diversity, EarlyView.
Dietary and microbial profiles of V. velutina larvae are dominated by Apidae and Firmicutes, respectively. DNA metabarcoding of larval meconium and gut samples reveals a significant positive correlation between prey richness and bacterial diversity in the invasive hornet V. velutina. Multiple significant correlations exist between dietary and microbial
Cayetano Herrera, Iris Alemany, Mar Leza, José A. Jurado‐Rivera   +3 more
wiley   +1 more source

Diagnostic value of metagenomic next-generation sequencing in atypical brucellosis: a case report. [PDF]

Front Med (Lausanne)
Ao D, Li X, Zhang G, Ma H, Yang L, Tian H, Ao S, Feng J, Geng W.   +8 more
europepmc   +1 more source

A Comparison of Endodontic Microbiomes Associated With Symptomatic and Asymptomatic Apical Periodontitis by Next‐Generation Sequencing

International Endodontic Journal, EarlyView.
ABSTRACT Aim This cross‐sectional study aimed to compare the endodontic microbiome assessed from root canals of teeth associated with either symptomatic or asymptomatic apical periodontitis and analysed by 16S rDNA gene sequencing. Methodology 60 teeth presenting clinical and radiographic signs of symptomatic or asymptomatic apical periodontitis (n ...
David Donnermeyer, Edgar Schäfer, Daniel Hagenfeld, Benjamin Ehmke, Karola Prior, Dag Harmsen, Madgalena Ibing, Sebastian Bürklein, Thomas Gerhard Wolf, Johannes Matern   +9 more
wiley   +1 more source

Metagenomic Next-Generation Sequencing Diagnosis of Streptococcus agalactiae Meningitis in a Diabetic Patient. [PDF]

Cureus
He X, Wang M, Sun T, Tang J, Zeng Y.
europepmc   +1 more source

Hematopathology Practice in the Digital Era: What has Changed?

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Hematopathology workflows are complex, since they include numerous data points necessary for guiding further testing, diagnosis, and patient management. The workflows start with complete blood cell counts, with subsequent morphologic evaluation of peripheral blood (PB) and bone marrow (BM).
Olga Pozdnyakova
wiley   +1 more source

Use of metagenomic next-generation sequencing to diagnose <i>Tropheryma whipplei</i> infection-related pneumonia: A case report. [PDF]

Exp Ther Med
Luo Y, Ding H, Pan J, Xu G.
europepmc   +1 more source

Defining the tumor microenvironment of non‐small cell lung cancer

Immunology &Cell Biology, EarlyView.
The tumor microenvironment (TME) in non‐small cell lung cancer is highly heterogeneous, both at a patient level and tumor microenvironment resolution. Defining the tumor microenvironment from patient‐responders and non‐responders will aid in the development of targeted therapeutics specific for each individual patient.
Kidane Siele Embaye, Tony Blick, Vahid Yaghoubi Naei, Ken O'Byrne, Brett G. M. Hughes, Arutha Kulasinghe   +5 more
wiley   +1 more source