Results 181 to 190 of about 4,663,034 (296)

Application of metagenomic next-generation sequencing in HIV-negative hematogenous disseminated tuberculosis. [PDF]

Front Cell Infect Microbiol
Luo L, Zhan J, Wang Z, Du X, Li N.
europepmc   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

Diagnostic and Therapeutic Impact of Metagenomic Next-Generation Sequencing in Tuberculous Osteoarticular Infections with Negative or Confounding Conventional Cultures. [PDF]

Infect Drug Resist
Xue Z, Li H, Wang X, Cai Y, Huang Z, Li W, Su Y, Wu Z, Fang X, Zhang W.   +9 more
europepmc   +1 more source

Analysis of individualized brain–gut association networks and transcriptional patterns in major depressive disorder

Interdisciplinary Medicine, EarlyView.
Individualized brain–gut association networks suggest potential neuropathological mechanisms in MDD and MDDSI. Multilevel brain–gut association changes involving HSV‐1 and inflammation may be relevant to MDD, whereas alterations related to insulin metabolism may play a potential role in the neuropathological mechanisms of MDDSI.
Wei Wang, Baoyuan Zhu, Yuanyuan Huang, Liqin Liang, Zhaobo Li, Yunheng Diao, Minxin Guo, Heng Zhang, Jing Zhou, Fengchun Wu, Kai Wu   +10 more
wiley   +1 more source

Correction: The application prospect of metagenomic next-generation sequencing technology in diagnosing suspected lower respiratory tract infections. [PDF]

Front Cell Infect Microbiol
Li W, Zhao M, Wu W, Chen G, Hang Y, Zheng H, Gao Z, Liu J, Zhao Y.   +8 more
europepmc   +1 more source

Advancements and prospects in bioinformatics and omics for colorectal cancer: A dual bibliometric analysis of global trends and top cited publications

Journal of Intelligent Medicine, EarlyView.
This dual bibliometric analysis examined 5129 publications and the top 100 most cited publications on bioinformatics and omics in colorectal cancer (2004–2025) from the Web of Science Core Collection. Using SCImago Graphica, VOSviewer, CiteSpace, and R Studio, we analyzed global trends, countries/regions, institutions, journals, authors, references ...
Yue Huang, Ziye Peng, Xiangyu Wang, Likun Yang, Yifei Gao, Ximo Wang, Jiaxin Li, Zhengcun Pei   +7 more
wiley   +1 more source

Metagenomic Next-Generation Sequencing Analysis of Pathogens in Infected Wounds from Dog and Cat Bites - China, 2021-2025. [PDF]

China CDC Wkly
Huang L, Wang L, Wang X, Zhang X, Yu X, Yang J, Zhang W, Yang J, Ji W, Cao Y, Zheng Y, Gai W, Jiang M, Liang Y.   +13 more
europepmc   +1 more source

Betaine‐, xylitol‐, and extra virgin olive oil–based toothpaste modulates inflammation and oral nitric oxide pathway: Clinical trial in gingivitis

Journal of Periodontology, EarlyView.
Abstract Background Gingivitis is a prevalent and reversible inflammatory condition driven by microbial dysbiosis. Beyond plaque control, interest has grown in oral hygiene formulations capable of modulating inflammation while preserving key microbial functions. Extra virgin olive oil (EVOO), together with xylitol and betaine, has demonstrated clinical
Francisco Mesa, Alejandro Rodríguez‐Agurto, Marco Bonilla, Debora Rodríguez‐Vilaboa, Beatriz Rodríguez‐Vilaboa, Manuel Bravo   +5 more
wiley   +1 more source

Metagenomic Next-Generation Sequencing Improves the Diagnosis Efficiency of Mixed Periprosthetic Joint Infections

Infection and Drug Resistance
Zibo Zhou, Yanhua Song, Yafang Yan, Yan Zheng Department of Clinical Laboratory, Zhengzhou Orthopaedics Hospital, Zhengzhou, Henan, 450000, People’s Republic of ChinaCorrespondence: Yanhua Song, Department of Clinical Laboratory, Zhengzhou Orthopaedics ...
Zhou Z, Song Y, Yan Y, Zheng Y
doaj  

Application of metagenomic next-generation sequencing in gastrointestinal infections in children after allogeneic hematopoietic stem cell transplantation. [PDF]

Front Cell Infect Microbiol
Xu Z, Wang Y, Zhang X, Guo F, Chen J, Geng H, Li Y, Gao Y.   +7 more
europepmc   +1 more source