Results 171 to 180 of about 4,663,034 (296)

Application of Metagenomic Next-Generation Sequencing in the Diagnosis of Pneumonia in Patients With Cancer. [PDF]

Cancer Med
Qin R, Wang C, Cong M, Tian L, Li N.
europepmc   +1 more source

Explore the Application Value of Metagenomic Next-Generation Sequencing of Bronchoalveolar Lavage Fluid in the Early Diagnosis of Pulmonary Tuberculosis [PDF]

Yangni Lu,1,* Chunlan Zhang,1,* Jianlin Wu,1 Xianli Xu,1 Ailian Lu,1 Huiya Huang,2 Maowei Chen1 1Department of Infectious Diseases, Wuming Hospital Affiliated to Guangxi Medical University, Nanning, Guangxi, People’s Republic of China ...
Wu J, Lu Y, Chen M, Huang H, Zhang C, Xu X, Lu A   +6 more
core  

Monocyte inflammation and adaptive immune dysfunction in severe Klebsiella pneumoniae pneumonia

iMeta, EarlyView.
Severe Klebsiella pneumoniae pneumonia combines intense inflammation with failure to control infection, yet the cellular basis is unclear. Using a severity‐focused single‐cell atlas of 708,894 peripheral blood mononuclear cells from 100 individuals, complemented by plasma protein measurements and flow cytometry, we show that disease severity redirects ...
Hongquan Chen, Xiaoling Wang, Xiang Liu, Kui Dong, Yanying Feng, Min Yuan, Shiyi Wang, Fangfang Fan, Yong Tian, Zhiming Kang, Xiushuai Du, Chaolu Hasi, Hong Lu, Wei Guan, Xu Chen, Mengyu Cheng, Wei Wei, Nan Guo, Zhiguo Liu, Xiaotong Qiu, Yiwei Shi, Kun Xiao, Yi Wang, Zhenjun Li   +23 more
wiley   +1 more source

Metagenomic next-generation sequencing to diagnose atypical severe scrub typhus

Journal of Microbiology, Immunology and Infection, 2022
Zuan Zhan, Chun-Fan Li, Jian Liu, Chun-Shui Cao, Liang Huang   +4 more
doaj   +1 more source

Metagenomic next-generation sequencing for tuberculosis diagnosis: enhanced performance and cost-effectiveness. [PDF]

Microbiol Spectr
Zhou X, Wei G, Song T, Yu Y, Chen J, Long J, Tao X, Zhang J, Jiang L.   +8 more
europepmc   +1 more source

Gut Enterococcus faecium derived leucic acid mediates the antiobesity effect of dietary fiber

iMeta, EarlyView.
This study identified Enterococcus faecium as a gut bacterium with anti‐obesity activity, which alleviated adipocyte hypertrophy, dyslipidemia, and hepatic steatosis by converting leucine into leucic acid (LEA) to regulate mitochondrial oxidative phosphorylation.
Baifei Hu, Qianru Gao, Junmin Hui, Mengqiong Wang, Haiyan Gao, Kai Li, Junping Zheng, Zhe Dai, Songlin Liu, Hongtao Liu   +9 more
wiley   +1 more source

Clinical application value of metagenomic next-generation sequencing in children with fever of unknown origin. [PDF]

Front Pediatr
Liu S, Wang S, Li J.
europepmc   +1 more source

Different gut microbiome dysbioses impact the evolutionary fate of hypervirulent Klebsiella pneumoniae

iMeta, EarlyView.
Transient exposure to ampicillin results in restructuring of microbiota to favor oxygen‐tolerant bacteria, whereas osmotic laxative perturbation preserves Bacteriodota. Ampicillin‐ but not laxative‐exposed environment favors establishment of rmpA phase variants that lost hypermucoviscosity but short‐chain fatty acids present in the laxative‐exposed gut
Carey Lim, Jialing Zheng, Guoxiang Cheam, Melvin Yong, Hanrong Chen, Andrew Ting, Yahua Chen, Qingqing Wang, Niranjan Nagarajan, Yunn‐Hwen Gan   +9 more
wiley   +1 more source

Clinical features of Q fever confirmed by plasma metagenomic next-generation sequencing. [PDF]

Front Immunol
Chen M, Zhou H, Zhou Z, He Y, Jiang Y.
europepmc   +1 more source

High‐Sugar Diet and Intestinal Diseases: A Shared Microbiota–Barrier–Immunity–Metabolism Axis in Inflammatory Bowel Disease, Food Allergy, and Colorectal Cancer

iNew Medicine, EarlyView.
ABSTRACT The global incidence of intestinal diseases—including food allergy, inflammatory bowel disease (IBD), and colorectal cancer (CRC)—continues to escalate in parallel with the expansion of the “Western diet,” within which the high‐sugar diet (HSD) has emerged as a pivotal yet under‐recognized dietary driver.
Yuchen Wang, Yajuan Wu, Huayang Sheng, Shouhong Jiang, Jinping Cheng, Ye Kuang, Miao Liu, Lei Feng, Yanan Sun, Jinzhi Duan   +9 more
wiley   +1 more source