Results 161 to 170 of about 4,663,034 (296)

Application of metagenomic next-generation sequencing in children with pneumonia of unknown etiology. [PDF]

Front Cell Infect Microbiol
Huang H, Fu Y, Liu E, Bai K, Li J, Liu C, Deng Y, Xu F.   +7 more
europepmc   +1 more source

Sequence‐identical microbial genomes with disparate taxonomy: A large‐scale redundancy analysis in NCBI genome database

iMetaOmics, EarlyView.
Public microbial genome repositories (such as NCBI) contain thousands of sequence‐identical genome assemblies assigned to different taxonomic lineages, potentially inflating microbial diversity and introducing bias into comparative genomics, metagenomics, and pathogen surveillance.
Niharika Saraf, Gaurav Sharma
wiley   +1 more source

Metagenomic Next-Generation Sequencing of Bronchoalveolar Lavage Fluids Improves Pathogen Detection and Antimicrobial Stewardship in Lower Respiratory Tract Infections: A Retrospective Study

Infection and Drug Resistance
Xiangsong Ma,1 Qinqin Zhang,1,2 Xuelian Ji,1 Yun Xia,1 Ju Cao,1 Xiuyu Xu1 1Department of Laboratory Medicine, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 2Department of Laboratory Medicine,
Ma X, Zhang Q, Ji X, Xia Y, Cao J, Xu X
doaj  

Correction: Unmasking the mimic: vertebral alveolar echinococcosis diagnosed by metagenomic next‑generation sequencing. [PDF]

Infection
Kruis T, Wassermann M, Graf B, Lührig K, Menzel P, Schwarzer R, Ziegler J, Isner C.   +7 more
europepmc   +1 more source

Bronchoalveolar Lavage Fluid Metagenomic Second-Generation Sequencing Assists in Guiding the Treatment of Visceral Leishmaniasis: A Case Report [PDF]

Jian Li,1,* Li Liu,2,* Zhiyun Gao,1 Xia Chuai,3 Xiaokun Liu,4 Xiaobo Zhang,2 Xinyu Zhang,2 Xiaoqing Su,2 Qian Xu,2 Zhuojun Deng2 1Department of Pathogenic Biology, Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China ...
Liu X, Li J, Liu L, Chuai X, Zhang X, Xu Q, Deng Z, Gao Z, Su X   +8 more
core  

Multi‐omics reveals gastrointestinal metabolic disorder‐induced diarrhea in postpartum dairy cows

iMetaOmics, EarlyView.
Nutritional diarrhea is a pervasive, costly challenge in dairy production. Using integrated metagenomic and metabolomic profiling, we identified coordinated microbial and metabolic alterations across the rumen, hindgut, and serum. In the rumen, enrichment of Prevotella sp.
Weixuan Tang, Yangyi Hao, Jiawei Zhang, Yajing Wang, Zhijun Cao, Hongjian Yang, Wei Wang, Shengli Li   +7 more
wiley   +1 more source

Metagenomic and culture‐based insights into host and plasmid contexts of high‐risk ARGs in poultry farm environments

iMetaOmics, EarlyView.
Shotgun metagenomics and culture‐based isolate genomics revealed position‐associated high‐risk antibiotic resistance genes (ARGs) signals across poultry manure piles and surrounding soils. Culture‐confirmed Enterobacteriaceae and IncHI2A‐related blaNDM‐5 plasmid backgrounds further highlight priority host‐ARG‐plasmid contexts for farm antimicrobial ...
Yaling Wang, Lianwei Ye, Linan He, Zhenlong Wu, Yiwen Yang, Sheng Chen   +5 more
wiley   +1 more source

Clinical utility of metagenomic next-generation sequencing in infants with severe infections. [PDF]

Front Microbiol
Gao Y, Huang Y, Li W, Huang Y, Zhao X, Chu C, Zhang X, Chen J, Wang Y, Li Y, Geng H.   +10 more
europepmc   +1 more source

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Pulmonary Nocardiosis Diagnosed by Plasma Metagenomic Next-Generation Sequencing in a Patient With Recurrent Febrile Neutropenia. [PDF]

Case Rep Infect Dis
Vega Brizneda M, Lum J, Wang H, Yetmar ZA.   +3 more
europepmc   +1 more source