Benchmarking gut microbiome indices within and across populations
We compared 10 widely used gut microbiome indices in 12,561 American Gut Project participants and 10 external cohorts, testing how well each distinguished people with healthy lifestyles, responded to 79 environmental factors, and associated with 14 chronic conditions. No single index performed best on all three tasks.
Yu Sun +6 more
wiley +1 more source
Correction: Unmasking the mimic: vertebral alveolar echinococcosis diagnosed by metagenomic next‑generation sequencing. [PDF]
Kruis T +7 more
europepmc +1 more source
Metagenomic Next-Generation Sequencing in Central Nervous System Angiostrongyliasis
Liao, Qiong, Zhu, Yu, Wen, Yang
openaire +2 more sources
Underrecognized Q fever and rickettsial diseases across China
Q fever and rickettsial diseases are underrecognized causes of fever of unknown origin in China, with Coxiella burnetii and Orientia tsutsugamushi predominating. We identify Rickettsia bellii‐like sequences in human clinical specimens and highlight unexpected pediatric detections that warrant further investigation of possible exposure patterns ...
Tian Qin +6 more
wiley +1 more source
Xiangsong Ma,1 Qinqin Zhang,1,2 Xuelian Ji,1 Yun Xia,1 Ju Cao,1 Xiuyu Xu1 1Department of Laboratory Medicine, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 2Department of Laboratory Medicine,
Ma X, Zhang Q, Ji X, Xia Y, Cao J, Xu X
doaj
Application of metagenomic next-generation sequencing in children with pneumonia of unknown etiology. [PDF]
Huang H +7 more
europepmc +1 more source
Butyrate ameliorates acute‐on‐chronic liver failure by regulating macrophage polarization
Multi‐omics profiling identifies progressive microbiota‐metabolism‐immunity axis dysfunction in acute‐on‐chronic liver failure (ACLF), characterized by gut dysbiosis, reduced butyrate production, intestinal barrier disruption, microbial translocation, and pro‐inflammatory macrophage polarization, thereby exacerbating hepatic inflammation and fibrosis ...
Jing Xiao +10 more
wiley +1 more source
Utility of Metagenomic Next-generation Sequencing of Plasma for Infectious Pathogens
William J Muller, Sonali Chaudhury
openaire +2 more sources
Lactobacillus derived small RNAs protect against Klebsiella pneumoniae infection
This study reveals that plant‐derived natural products confer protection against carbapenem‐resistant Klebsiella pneumoniae (CRKP) infection via remodeling the gut microbiota, with Lactobacillus identified as the core beneficial genus. Mechanistically, Lactobacillus murinus (L.
Tingting Xu +5 more
wiley +1 more source
Bronchoalveolar Lavage Fluid Metagenomic Second-Generation Sequencing Assists in Guiding the Treatment of Visceral Leishmaniasis: A Case Report [PDF]
Jian Li,1,* Li Liu,2,* Zhiyun Gao,1 Xia Chuai,3 Xiaokun Liu,4 Xiaobo Zhang,2 Xinyu Zhang,2 Xiaoqing Su,2 Qian Xu,2 Zhuojun Deng2 1Department of Pathogenic Biology, Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China ...
Liu X +8 more
core

