Results 141 to 150 of about 6,252 (250)

Exploring the Application of Metagenomic Next-Generation Sequencing in the Diagnosis of Unexplained Pulmonary Infection

Sida Chen, Ling Wen, Jintao Ou, Yuting Lai, Yan Shen Department of Respiratory, Shenzhen Longgang Central Hospital, Shenzhen, Guangdong, 518000, People’s Republic of ChinaCorrespondence: Yan Shen, Shenzhen Longgang Central Hospital 6082 Longgang ...
Lai Y, Wen L, Ou J, Chen S, Shen Y
core  

Changes in the gut microbiome during fasting‐induced molting and its effects on gut–liver function

iMetaOmics, EarlyView.
During fasting, harmful microbiota and metabolites rise, triggering intestinal injury and activation of the TGF‐β signaling pathway, which enhances intestinal stem cell proliferation. Concurrently, hepatic function declines, indicated by increased hepatic and serum bile acids and upregulation of the non‐classical bile acid synthesis pathway.
Hao Zhang, Zhixuan Luo, Jun Zhang, Chenxu Wang, Yadong Tian, Donghua Li, Yujie Guo, Yanhua Zhang, Wenting Li, Yujie Gong, Xiangtao Kang, Ruirui Jiang   +11 more
wiley   +1 more source

Biodiversity and distribution of polar freshwater DNA viruses

, 2015
Viruses constitute the most abundant biological entities and a large reservoir of genetic diversity on Earth. Despite the recent surge in their study, our knowledge on their actual biodiversity and distribution remains sparse.
López-Bueno, Alberto, Pearce, David, Pearce, David A., Alcamí, Antonio, Aguirre de Cárcer, Daniel   +4 more
core   +1 more source

Genomic epidemiology and lineage‐specific risk stratification of tet(X4)‐mediated tigecycline resistance along the pork production chain: A One Health perspective

iMetaOmics, EarlyView.
Genome surveillance across a swine‐associated One Health continuum in China shows that slaughterhouses act as major enrichment nodes for tet(X4)‐mediated tigecycline resistance, driven by putative clonal transmission and stable plasmid backbones. Integrating global datasets enables lineage‐specific risk stratification, highlighting key control points ...
Qin Wang, Qiwu Yuan, Xuan Chen, Yujing Zhong, Ke Wu, Renqiao Wen, Luya Liu, Xiaoqin Wang, Cui Li, Hongning Wang, Changwei Lei   +10 more
wiley   +1 more source

Gut Microbiota: A Reservoir for Extraintestinal Bacterial Infections in Febrile Term Infants

iLABMED, EarlyView.
Ran Wang, Renqiang Yu
wiley   +1 more source

Metagenomic mining of environmental resistomes: Comparative performance of deep learning and alignment‐based annotation methods

iMetaOmics, EarlyView.
Antimicrobial resistance (AMR) in marine environments poses intricate challenges due to the ecological complexity of microbial communities and environmental gradients. This study compares various antimicrobial resistance gene (ARG) annotation tools and databases, focusing on deep learning approaches versus traditional alignment‐based methods, to ...
Joeselle M. Serrana, Francisco J. A. Nascimento, Malte Posselt   +2 more
wiley   +1 more source

Applications and Challenges of Artificial Intelligence in Predicting Antimicrobial Resistance

iLABMED, EarlyView.
Wenjuan Wu, Zhexiao Ma
wiley   +1 more source

microeco 2: A comprehensive R package for downstream analysis of microbiome omics data

iMeta, EarlyView.
The current version 2.0 of the microeco package represents a substantial update compared to the previously published version. Key enhancements include the addition of new classes, integration of a broader suite of analytical methods, a comprehensive overhaul of the parameter system, improved connectivity between statistical analysis and visualization ...
Chi Liu, Xiangzhen Li, Felipe R. P. Mansoldo, Tong Chen, Fanzheng Meng, Ruixiang Tang, Siyu Zhou, Qinghua Yang, Ruixin Shao, Minjie Yao   +9 more
wiley   +1 more source

Beyond Traditional Screening: The Future of Heart Failure Detection With Biomarkers and AI

iNew Medicine, EarlyView.
Advancing HF Screening: Integrating Technology and Risk Factors Across Eras. This diagram provides a comprehensive review of the historical developments and projected trends of heart failure (HF) screening methodologies, with the prevalent risk factors for HF depicted at the base.
Xiaofeng Fang, Yinbo Xu, Yiting Zhao, Liuyi Li, Zhengyi Cheng, Zhongqi Zhang, Yuhang Luo, Qiaoling Liu, Chen Gong, Shichun Shen   +9 more
wiley   +1 more source

Multimodal MRI and multiomics reveal high‐risk neurophenotype in brain‐gut circuits as therapeutic target for Crohn's disease

Interdisciplinary Medicine, EarlyView.
Through a translational framework combining prospective dual‐center clinical cohorts with dextran sulfate sodium‐induced colitis models, this work integrated advanced neuroimaging, multi‐omics and neuromodulation interventions to redefine the high‐risk neurophenotype as a sustained pathogenic driver rather than a mere phenomenon, proposing brain‐gut ...
Xuehua Li, Ruonan Zhang, Xiaodi Shen, Shaochun Lin, Chuhuai Wang, Weikai Zheng, Weimiao Kong, Zihao Lin, Rongchang Li, Caiguang Liu, Xin Cao, Li Huang, Weitao He, Jinjiang Lin, Haijie Wang, Zhoulei Li, Marietta Iacucci, Subrata Ghosh, Zhenpeng Peng, Canhui Sun, Minhu Chen, Guang Yang, Yejun Wang, Ren Mao, Shi‐Ting Feng   +24 more
wiley   +1 more source