Results 141 to 150 of about 58,932 (285)

The Expanding Landscape of Microbiota Medicine: Indications, Therapeutic Modalities, and the Path Towards Integrative Microbiome‐Targeting Healthcare

Microbiota Medicine Research, EarlyView.
ABSTRACT The growing recognition of the microbiome's role in human health has propelled the emergence of microbiota medicine—a new discipline integrating microbiology, multi‐omics, and clinical science. Advances in sequencing, data integration, and interventions such as fecal microbiota transplantation (FMT) have transitioned the field from ...
Min Dai, Yisha Lin, Renyou Gan, Xiaotao Shen, Shin Young Park, Sunjae Lee, Qi Su   +6 more
wiley   +1 more source

Nanopore Sequencing for HPV in Oropharyngeal Squamous Cell Carcinoma and Benign Tonsil Specimens

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objectives Human papillomavirus (HPV) accounts for the majority of oropharyngeal squamous cell carcinoma (OPSCC) cases in the United States but understanding the prevalence of high‐risk HPV in oropharyngeal tissue remains poor. We evaluated nanopore sequencing, a novel rapid, and long‐read sequencing platform, on OPSCC tissue and tested it in ...
Mikayla G. Hubbard, Guang‐Sheng Lei, Robert Emerson, Danielle Schreiber, Thomas E. Davis, Diane W. Chen   +5 more
wiley   +1 more source

Omics Insights Into the Effects of Highbush Blueberry and Cranberry Crop Agroecosystems on Honey Bee Health and Physiology

PROTEOMICS, EarlyView.
ABSTRACT Honey bees (Apis mellifera) are vital pollinators in fruit‐producing agroecosystems like highbush blueberry (HBB) and cranberry (CRA). However, their health is threatened by multiple interacting stressors, including pesticides, pathogens, and nutritional changes.
Huan Zhong, Yuming Shi, Aleksandra Kozlova, Renata Moravcova, Jason C. Rogalski, Aidan Jamieson, Lance Lansing, Kyung‐Mee Moon, Xiaojing Yuan, Amanda S. Gregoris, Heather Higo, Julia Common, Ida M. Conflitti, Mateus Pepinelli, Lan Tran, Morgan Cunningham, Hosna Jabbari, Syed Abbas Bukhari, Sarah K. French, Rodrigo Ortega Polo, Shelley E. Hoover, Stephen F. Pernal, Pierre Giovenazzo, M. Marta Guarna, Amro Zayed, Leonard J. Foster   +25 more
wiley   +1 more source

Metagenomic Next-Generation Sequencing Reveals Tannerella forsythia in Lung Abscesses: A Retrospective Case Series Linking Smoking, Oral Health, and Diagnostic Challenges

Infection and Drug Resistance
Wen Wang, Qiongya Mo, Xuchun Ding,* Junjie Pan* Department of Respiratory and Critical Care Medicine, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, People’s Republic of China*
Wang W, Mo Q, Ding X, Pan J
doaj  

Exploring Costa Rica's fungal trends: Insights from digitized specimens

PLANTS, PEOPLE, PLANET, EarlyView.
Fungi are essential to tropical ecosystems but remain largely absent from conservation agendas. By analyzing over 78,000 fungal records from Costa Rica—a globally recognized biodiversity hotspot—this study reveals key patterns in fungal diversity, distribution, and seasonality.
Melissa Mardones, Julieta Carranza‐Velázquez, Carlos Rojas   +2 more
wiley   +1 more source

Metagenomic Next-Generation Sequencing Unveils Prognostic Microbial Synergism and Guides Precision Therapy in Candidemia: A Retrospective Cohort Study

Infection and Drug Resistance
Yuhui Chen,1,2 Meng Li,1,2 Xinai Gan,1,2 Yutong Wang,1,2 Xinzhu Tang,1,2 Yongzhao Zhou,3,4 Ting Niu1,5,6 1Department of Hematology, Institute of Hematology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 2West China School ...
Chen Y, Li M, Gan X, Wang Y, Tang X, Zhou Y, Niu T   +6 more
doaj  

Rethinking intensification: Biodiversity‐inclusive management sustains coconut yields

PLANTS, PEOPLE, PLANET, EarlyView.
Coconut palm expansion in West Africa will shape rural livelihoods and ecosystems. Our findings show that intensive practices reduce beneficial soil fungi and increase pathogens, threatening long‐term productivity. Lower‐intensity management that retains ground vegetation can sustain or boost yields while improving soil health.
Benjamin J. Roberts, C. M. ( Tilly) Collins, Konan Engueran Djaha, Hamish Duncalf‐Youngson, Konan Jean Louis, Hala N'klo, Emma Ransome, Doubi Bi Tra Serges, Jahcub Trew, Jake Williams, Vincent Savolainen   +10 more
wiley   +1 more source

Impact of Metagenomic Next-Generation Sequencing on Antibiotic Management in Pediatric Patients. [PDF]

Medicina (Kaunas)
Gonzalez A, Argotsinger J, Oram RJ, Miller JL.   +3 more
europepmc   +1 more source

Metagenomic Next-Generation Sequencing of Bronchoalveolar Lavage Fluids Improves Pathogen Detection and Antimicrobial Stewardship in Lower Respiratory Tract Infections: A Retrospective Study

Infection and Drug Resistance
Xiangsong Ma,1 Qinqin Zhang,1,2 Xuelian Ji,1 Yun Xia,1 Ju Cao,1 Xiuyu Xu1 1Department of Laboratory Medicine, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 2Department of Laboratory Medicine,
Ma X, Zhang Q, Ji X, Xia Y, Cao J, Xu X
doaj  

Inulin‐Butyrate Nanogel for Modulation of Gut Microbiome, Intestinal Barrier, and Regulatory T‐Cells in Colitis

Small, EarlyView.
IBD is driven by a vicious cycle of dysbiosis, barrier dysfunction, and immune dysregulation. We developed an inulin–butyrate conjugate nanogel (IBN) that accumulates in inflamed colon and releases butyrate via microbial inulinase/esterase. The inulin shell remodels the microbiome, while localized butyrate strengthens barrier integrity and promotes ...
Nayoon Park, Bom Lee, Hyeon‐Jeong Jeon, Ji Yeon Kim, Suyeon Park, Seong‐Eun Kim, Dong‐Kyu Lee, Yonghyun Lee   +7 more
wiley   +1 more source