Results 131 to 140 of about 4,937,404 (296)
Biological Diversity, EarlyView.Environmental nucleic acids (eNA) observations integrate temporal and ecological information across multiple dimensions of an ecological state. Repeated and complementary observations extend biomonitoring from state assessment toward reconstruction of ecological trajectories, including their direction, rate, pathways, progression, recovery, and ...
Wei Xiong, Aibin Zhan
wiley +1 more source
Moving towards third-generation sequencing technologies
, 2012 Within just the past few years, next-generation sequencing (NGS) platforms have reduced the cost of DNA sequencing by several orders of magnitude. With these lower costs, DNA sequencing is increasingly powerful as a single-data format onto which a broad ...
Janitz, Michael +3 more
core +1 more source
Ecography, EarlyView.The theory of island biogeography (TIB) remains contentious for microbes, as their immense dispersal potential and microscopic size may decouple diversity from classic isolation/area effects. We explicitly tested TIB scaling rules for soil bacteria and fungi across 20 oceanic islands using a rigorous multi‐scale framework that integrated high ...
Lan Liu +4 more
wiley +1 more source
Diagnostic efficacy of metagenomic next-generation sequencing for spinal infections
陆军军医大学学报Objective To comparatively evaluate the diagnostic value of metagenomic next-generation sequencing (mNGS) versus conventional microbial culture in spinal infections.
LIU Shuang, HE Jinyue, CHEN Hui
doaj +1 more source
Epilepsia, EarlyView.Abstract Objective The ketogenic diet (KD) is a high‐fat, low‐carbohydrate intervention widely used to treat drug‐resistant epilepsy, thought to reduce seizures through a combination of metabolic, neuronal, and microbiota‐dependent mechanisms. Additionally, recent studies suggest that the anticonvulsant effects of KD require the gut microbiota, with ...
Casey H. Meili +4 more
wiley +1 more source
Infection and Drug ResistanceJiayi Chen,* Zixiang Pang,* Chengyu Qin, Zuhai Huang, Yuanming Chen Department of Spinal Orthopedics, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People’s Republic of China*These authors ...
Chen J, Pang Z, Qin C, Huang Z, Chen Y
doaj
Exploring the Application of Metagenomic Next-Generation Sequencing in the Diagnosis of Unexplained Pulmonary Infection [PDF]
Sida Chen, Ling Wen, Jintao Ou, Yuting Lai, Yan Shen Department of Respiratory, Shenzhen Longgang Central Hospital, Shenzhen, Guangdong, 518000, People’s Republic of ChinaCorrespondence: Yan Shen, Shenzhen Longgang Central Hospital 6082 Longgang ...
Lai Y, Wen L, Ou J, Chen S, Shen Y
core
Gut‐microbiota‐brain Axis and post‐traumatic epilepsy
Epilepsia Open, EarlyView.Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley +1 more source
Epilepsia Open, EarlyView.Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar +4 more
wiley +1 more source
ParMap, an Algorithm for the Identification of Complex Genomic Variations in Nextgen Sequencing Data [PDF]
, 2010 Next-generation sequencing produces high-throughput data, albeit with greater error and shorter reads than traditional Sanger sequencing methods. This complicates the detection of genomic variations, especially, small insertions and deletions.
Raul Rabadan +4 more
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