Results 121 to 130 of about 4,663,034 (296)

Clinical Value of Sampling Time of Metagenomic Next-Generation Sequencing in Patients with Severe Pneumonia

, 2023
Shixiao Li,1 Peng Zhou,2 Lihong Yang,1 Tianbin Tang,1 Jiajia Qin,1 Jiao Qian,1 Shen Bo,1 Sufei Yu1 1Department of Clinical Microbiology Laboratory, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, People ...
Qian J, Li S, Yang L, Zhou P, Yu S, Qin J, Tang T, Bo S   +7 more
core  

Unbiased metagenomic next-generation sequencing of blood from hospitalized febrile children in Gabon

, 2020
Unbiased metagenomic next-generation sequencing of blood from hospitalized febrile children in ...
Isabella Eckerle (381546), Samuel Cordey (74802), Martin Peter Grobusch (9287756), Benjamin Mordmüller (211841), Florian Laubscher (6535340), José Francisco Fernandes (9287753), Mylène Docquier (105372), Laurent Kaiser (74805), Jana Held (224956)   +8 more
core   +1 more source

Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing

Animal Research and One Health, EarlyView.
Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley   +1 more source

Acidogenic fermentation of pretreated food waste under psychrophilic conditions for volatile fatty acids production

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Mixed‐culture fermentation generally produces volatile fatty acids (VFAs) as a mixture of C2–C6 acids. Among operational parameters, temperature has a distinct effect on the microorganisms' metabolic activity, which can shift the composition of the metabolites.
Reema Kumar, Guneet Kaur, Satinder K. Brar, Patrik Lennartsson, Amir Mahboubi   +4 more
wiley   +1 more source

Comparing the diagnostic value of targeted with metagenomic next-generation sequencing in immunocompromised patients with lower respiratory tract infection

Annals of Clinical Microbiology and Antimicrobials
Background Accurate identification of the etiology of lower respiratory tract infections (LRTI) is crucial, particularly for immunocompromised patients with more complex etiologies.
Muyun Wei, Shaowei Mao, Shuangshuang Li, Kangyi Gu, Dejian Gu, Shengjie Bai, Xinhua Lu, Min Li   +7 more
doaj   +1 more source

Acute Q fever pneumonia diagnosed by metagenomic next-generation sequencing

Journal of Infection in Developing Countries
Introduction: Q fever, a zoonotic disease caused by Coxiella burnetii (C. burnetii), presents diagnostic challenges due to its clinical and radiological nonspecificity, which often mimics community-acquired pneumonia, coupled with the limitations of ...
Bin Liu, Peng Huang, Yanchao Liang, Shuangbo Liu, Fangwei Chen, Xiping Luo, Tengjuan Xu, Bo Xie   +7 more
doaj   +1 more source

Next Generation Sequencing as a Tool for Noninvasive Prenatal Tests

, 2016
Prenatal diagnosis involves all available procedures to determine the health status of a fetus or embryo before birth, including screening for genetically based diseases. Two mechanisms cause genetic or gene-related diseases.
Cogulu O., Ozgur Cogulu
core   +1 more source

Biogas production from Opuntia stricta Haw.: microbial diversity and solid load influence on sludge recycle systems

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract The search for alternative and sustainable energy sources becomes urgent as energy demand increases and fossil fuels become less available, especially in water‐scarce regions such as the Brazilian semi‐arid region, where current projections of global warming and the expansion of arid and semi‐arid zones point to a future of desertification ...
Wallysson K. P. Barros, Íthalo B. S. de Abreu, Elias G. M. Silva, João V. P. Tavares, Bruna K. O. Silva, Joyce G. W. Siqueira, Rafael B. de Souza, Rômulo S. C. Menezes, Everardo V. S. B. Sampaio, José Antonio Pérez‐Pimienta, Emmanuel D. Dutra   +10 more
wiley   +1 more source

Metagenomic Next-Generation Sequencing in Clinical Microbiology

Indian Journal of Medical Microbiology, 2019
Jobin John, Jacob, Balaji, Veeraraghavan, Karthick, Vasudevan   +2 more
openaire   +2 more sources

Precision medicine in paediatrics: Progress and priorities

British Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain, Claire Booth, Joseph F. Standing, Charlotte I. S. Barker   +3 more
wiley   +1 more source