Results 111 to 120 of about 6,252 (250)

Cunningham: a BLAST Runtime Estimator

, 2011
BLAST is arguably the single most important piece of software ever written for the biological sciences. It is the core of most bioinformatics workflows, being a critical component of genome homology searches and annotation.
Malcolm Matalka, James R. White, James White, Samuel V. Angiuoli, W. Florian Fricke, Samuel Angiuoli   +5 more
core   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Comparing the diagnostic value of targeted with metagenomic next-generation sequencing in immunocompromised patients with lower respiratory tract infection

Annals of Clinical Microbiology and Antimicrobials
Background Accurate identification of the etiology of lower respiratory tract infections (LRTI) is crucial, particularly for immunocompromised patients with more complex etiologies.
Muyun Wei, Shaowei Mao, Shuangshuang Li, Kangyi Gu, Dejian Gu, Shengjie Bai, Xinhua Lu, Min Li   +7 more
doaj   +1 more source

Vicatia thibetica de Boiss Crude Polysaccharide Delay the Aging of the Heart and Kidneys

Food Bioengineering, EarlyView.
Vicatia thibetica de Boiss crude polysaccharide (VTCP) attenuates cardiorenal aging by reducing oxidative stress, suppressing inflammation, and alleviating fibrosis. In naturally aged mice, VTCP remodels the gut microbiota, enriching beneficial short‐chain fatty acid‐producing bacteria. We propose that VTCP protects the heart and kidneys via modulation
Daoxu Zhang, Chengyi Wu, Zhiyang Ding, Yunyu Hong, Yehan Lu, Kunpeng Zhou, Ruixuan Deng, Laijia Li, Chao Li, Yongcheng Yang, Conglong Xia, Jian Li, Wenwen Liu, Faliang An, Zelan Hu   +14 more
wiley   +1 more source

Metagenomic Next-Generation Sequencing Direct Diagnosis of Mixed Bacterial Meningitis in a Child: A Case Report

Wei Wang,* Yujuan Wang,* Xiaowei Xin, Yi Yin, Chun Zhao, Youpeng Jin Department of Pediatric Intensive Care Unit, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province, 250021, People’s Republic of
Yin Y, Zhao C, Wang W, Wang Y, Xin X, Jin Y   +5 more
core  

Application of Metagenomic Next-Generation Sequencing in HIV-Infected Patients with Bloodstream Infections

Huiting Liu, Tianzhen Xu, Hongxin Fu, Bohao Dai, Yirui Xie State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of ...
Liu H, Xie Y, Dai B, Fu H, Xu T
core  

Point-counterpoint: Should we be performing metagenomic next-generation sequencing for infectious disease diagnosis in the clinical laboratory?

, 2020
With established applications of next-generation sequencing in inherited diseases and oncology, clinical laboratories are evaluating the use of metagenomics for identification of infectious agents directly from patient samples, to aid in the diagnosis of
Miller, Steve, Rodino, Kyle G., Miller, Melissa B, Rodino, Kyle G, Chiu, Charles, Miller, Melissa B.   +5 more
core   +1 more source

Application of Metagenomic Next-Generation Sequencing in the Diagnosis of Infectious Keratitis

Journal of Ophthalmology
Purpose. To determine the advantages of next-generation metagenomic sequencing (mNGS) technology in the diagnosis and treatment of infectious keratitis (IK). Methods. A total of 287 patients with IK admitted to the Department of Ophthalmology of Nanjing First Hospital between August 2018 and December 2022 were analyzed retrospectively, and the ...
Xin-Yu Pan, Meng Wang, Yi-Dan Xu, Lin-Nong Wang   +3 more
openaire   +3 more sources

Rewiring nutrition: Chemical insights into the physiological and microbiological roles of food's microconstituents

Food Biomacromolecules, EarlyView.
Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley   +1 more source

Acute Q fever pneumonia diagnosed by metagenomic next-generation sequencing

Journal of Infection in Developing Countries
Introduction: Q fever, a zoonotic disease caused by Coxiella burnetii (C. burnetii), presents diagnostic challenges due to its clinical and radiological nonspecificity, which often mimics community-acquired pneumonia, coupled with the limitations of ...
Bin Liu, Peng Huang, Yanchao Liang, Shuangbo Liu, Fangwei Chen, Xiping Luo, Tengjuan Xu, Bo Xie   +7 more
doaj   +1 more source