Results 11 to 20 of about 975 (184)

Functionalizing Injectable Hydrogels with Cobalt-Based Metallacarboranes for Targeted Delivery in Triple-Negative Breast Cancer. [PDF]

Chembiochem
This study reports a biocompatible HA–lysine hydrogel loaded with cobalt metallacarborane (CoSAN) for targeted release into triple‐negative breast cancer cells. The system maintains CoSAN cytotoxicity, as confirmed by cell assays and imaging, representing an attractive approach toward a localised TNBC treatment.
Murphy N, González-Gómez R, Ashok N, O'Connell E, Fearnhead H, Tipping WJ, Faulds K, Tong W, Pandit A, Dwyer RM, Graham D, Farràs P.   +11 more
europepmc   +5 more sources

Stabilizing Anion–Anion Aggregates via Dihydrogen Bonds in Non‐Classical Inorganic Molecules

Aggregate
Coulomb's law predicts that like‐charge ions repel and avoid dimerization. However, a class of dimers between like‐charge ions is characterized. The [3,3’‐Fe(1,2‐C2B9H11)2]− (abbreviated as [o‐FESAN]−) represents an innovative non‐classical inorganic ...
Adnana Zaulet, Miquel Nuez‐Martinez, Pipsa Hirva, Reijo Sillanpää, Francesc Teixidor, Clara Viñas   +5 more
doaj   +2 more sources

Expanding the Range of Bioorthogonal Tags for Multiplex Stimulated Raman Scattering Microscopy. [PDF]

Angew Chem Int Ed Engl, 2023
Hyperspectral stimulated Raman scattering (SRS) microscopy with spectral phasor analysis enables the multiplex detection of bioorthogonal Raman groups in cells. Unmixing of the overlapping alkyne and deuterium signals together with the detection of metallacarboranes is reported within the cell‐silent region of the Raman spectrum.
Murphy N, Tipping WJ, Braddick HJ, Wilson LT, Tomkinson NCO, Faulds K, Graham D, Farràs P.   +7 more
europepmc   +3 more sources

Two Shared Icosahedral Metallacarboranes through Iron: A Joint Experimental and Theoretical Refinement of Mössbauer Spectrum in [Fe(1,2-C₂B₉H₁₁)₂]Cs. [PDF]

ACS Omega, 2023
SUBJECTS:Anions,Conformation,Energy,Molecular structure,Quantum mechanicsMössbauer and X-ray photoelectron spectroscopies (XPS) are complemented with high-level quantum-chemical computations in the study of the geometric and electronic structure of the ...
Marco JF, Dávalos-Prado JZ, Hnyk D, Holub J, Oña OB, Alcoba DR, Ferrer M, Elguero J, Lain L, Torre A, Oliva-Enrich JM.   +10 more
europepmc   +4 more sources

When the Ferrocene Analogy Breaks Down: Metallocene Transmetallation Chemistry

Angewandte Chemie, Volume 135, Issue 39, September 25, 2023., 2023
The transmetallation of a transition metal metallocene “like” compound is reported for the first time. While the parent ferrocene analogue Fe(bis)(dicarbollide) is inert to this reactivity its imidazolium and NHC functionalized derivatives undergo rapid transmetallation to Ir and Cu. Abstract Ferrocene 1 and its dianionic Fe(bis)(dicarbollide) analogue
Varun Tej Raviprolu, Phillip Farias, Veronica Carta, Hill Harman, Vincent Lavallo   +4 more
wiley   +2 more sources

Blue Emitting Star-Shaped and Octasilsesquioxane-Based Polyanions Bearing Boron Clusters. Photophysical and Thermal Properties

Molecules, 2020
High boron content systems were prepared by the peripheral functionalisation of 1,3,5-triphenylbenzene (TPB) and octavinylsilsesquioxane (OVS) with two different anionic boron clusters: closo-dodecaborate (B12) and cobaltabisdicarbollide (COSAN). TPB was
Justo Cabrera-González, Mahdi Chaari, Francesc Teixidor, Clara Viñas, Rosario Núñez   +4 more
doaj   +1 more source

Metallacarboranes as Photoredox Catalysts in Water [PDF]

Chemistry – A European Journal, 2020
AbstractMetallacarboranes with the shape of the Greek letter θ, such as [Co(C2B9H11)2]−, were tested, for the first time, as efficient photoredox catalysts in the oxidation of aromatic and aliphatic alcohols in water. Their efficiency is linked to their high solubility in water, their high oxidizing power (Co4+/3+), and their absence of fluorescence on
Isabel Guerrero, Zsolt Kelemen, Clara Viñas, Isabel Romero, Francesc Teixidor   +4 more
openaire   +4 more sources

Metallacarboranes for proton therapy using research accelerators: a pilot study

EPJ Techniques and Instrumentation, 2023
The feasibility of using an external beam microprobe facility to explore the biological effects generated by proton irradiation in cultured cells is demonstrated. An in-air irradiation set-up was developed that allows energy tuning and enables estimating
Teresa Pinheiro, Luís C. Alves, Victoria Corregidor, Francesc Teixidor, Clara Viñas, Fernanda Marques   +5 more
doaj   +1 more source

Cobaltabis(dicarbollide) ([o-COSAN]−) as Multifunctional Chemotherapeutics: A Prospective Application in Boron Neutron Capture Therapy (BNCT) for Glioblastoma [PDF]

, 2021
Purpose: The aim of our study was to assess if the sodium salt of cobaltabis(dicarbollide) and its di-iodinated derivative (Na[o-COSAN] and Na[8,8′-I2-o-COSAN]) could be promising agents for dual anti-cancer treatment (chemotherapy + BNCT) for GBM.
Bitonto, Valeria, Crich, Simonetta Geninatti, Guerreiro, Joana F., Laromaine, Anna, Marques, Fernanda, Mendes, Filipa, Muñoz-Juan, Amanda, Nuez-Martinez, Miquel, Pinto, Catarina I. G., Protti, Nicoletta, Teixidor, Francesc, Viñas, Clara, Xavier, Jewel Ann Maria   +12 more
core   +3 more sources

Employment of chiral columns with superficially porous particles in chiral separations of cobalt bis (dicarbollide) and nido‐7,8‐C2B9H12(1‐) derivatives

Chirality, Volume 35, Issue 12, Page 937-951, December 2023., 2023
Successful chiral separations of nido‐7,8‐C2B9H12(1‐) and [3,3′‐Co‐(1,2‐C2B9H11)2]− cobalt sandwich derivatives using hydroxypropylated beta‐cyclodextrin, vancomycin, and isopropylated cyclofructan CF‐6 bonded to superficially porous silica gel particles.
Ondřej Horáček, Umang Dhaubhadel, Josef Holub, Bohumír Grüner, Daniel W. Armstrong, Radim Kučera   +5 more
wiley   +1 more source