Results 1 to 10 of about 745 (163)
Iridium(III)-catalyzed remote B(9)−H alkylation of o-carboranes with nitrile template [PDF]
Nature CommunicationsCarboranes, unique three-dimensional analogs of benzene, have attracted considerable attention owing to their potential in medicine, catalysis, and materials science. Consequently, the introduction of functional groups into carborane clusters has emerged
Kyungsup Lee +7 more
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Site- and enantioselective B−H functionalization of carboranes [PDF]
Nature CommunicationsFunctionalization of carboranes, icosahedral boron−carbon molecular clusters, is of great interest as they have wide applications in medicinal and materials chemistry.
Kyungsup Lee +9 more
doaj +2 more sources
Carborane Nanomembranes. [PDF]
ACS NanoWe report on the fabrication of a boron-based two-dimensional (2D) material via electron irradiation-induced cross-linking of carborane self-assembled monolayers (SAMs) on crystalline silver substrates. The SAMs of 1,2-dicarba-closo-dodecarborane-9,12-dithiol (O9,12) were prepared on flat crystalline silver substrates and irradiated with low-energy ...
Frey M +8 more
europepmc +4 more sources
Boron Theranostic Nanoplatform Utilizing a GO@Carborane@Au Hybrid Framework for Targeted Delivery [PDF]
PharmaceuticsBackground: Boron neutron capture therapy (BNCT) represents a highly selective therapeutic modality for recalcitrant cancers, leveraging the nuclear reaction initiated by thermal neutron capture in boron-10 (10B) to deliver high-linear energy transfer ...
Václav Ranc, Ludmila Žárská
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Structure-Activity Relationships of closo- and nido-Carborane Erlotinib Analogs: Lipophilicity as a Key Modulator of Anti-Glioma Activity [PDF]
PharmaceuticalsBackground/Objectives: To enhance the anti-glioma activity of erlotinib, we previously developed a series of carborane-based analogs exploiting the concept of three-dimensional bioisosterism.
Belén Dávila +8 more
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Carboranes as unique pharmacophores in antitumor medicinal chemistry
Molecular Therapy: Oncolytics, 2022 Carborane is a carbon-boron molecular cluster that can be viewed as a 3D analog of benzene. It features special physical and chemical properties, and thus has the potential to serve as a new type of pharmacophore for drug design and discovery.
Yu Chen +10 more
doaj +1 more source
Carborane photochromism: a fatigue resistant carborane switch
Chemical Communications, 2021 A dithienylethene molecule involving carborane clusters shows remarkable fatigue resistance and high contrast visual colour changes when irradiated with alternating ultraviolet and visible light.
Chong Li +6 more
openaire +5 more sources
Nanomaterials, 2023 Carboranes are promising agents for applications in boron neutron capture therapy (BNCT), but their hydrophobicity prevents their use in physiological environments.
Tainah Dorina Marforio +3 more
doaj +1 more source
Comprehensive exploration of chemical space using trisubstituted carboranes
Scientific Reports, 2021 A total of 42 trisubstituted carboranes categorised into five scaffolds were systematically designed and synthesized by exploiting the different reactivities of the twelve vertices of o-, m-, and p-carboranes to cover all directions in chemical space ...
Yasunobu Asawa +6 more
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Pharmaceuticals, 2022 In this review, the history of boron’s early use in drugs, and the history of the use of boron functional groups in medicinal chemistry applications are discussed. This includes diazaborines, boronic acids, benzoxaboroles, boron clusters, and carboranes.
Katia Messner +2 more
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