Results 101 to 110 of about 19,930 (199)
Phosphonopeptides Revisited, in an Era of Increasing Antimicrobial Resistance [PDF]
, 2020 Given the increase in resistance to antibacterial agents, there is an urgent need for the development of new agents with novel modes of action. As an interim solution, it is also prudent to reinvestigate old or abandoned antibacterial compounds to assess
Anderson, Rosaleen +8 more
core +2 more sources
MicrobiologyOpen, Volume 15, Issue 1, February 2026.This study highlights the prevalence of multidrug‐ and carbapenem‐resistant Pseudomonas aeruginosa in pediatric cystic fibrosis patients, along with the presence of carbapenemase‐encoding genes and genetic profiles, suggesting clonal spread. These findings underscore the urgent need for surveillance and strategies to combat resistant strains and ...
Erfaneh Jafari +5 more
wiley +1 more source
Asp-120 Locates Zn2 for Optimal Metallo-β-lactamase Activity [PDF]
, 2007 Metallo-β-lactamases are zinc-dependent hydrolases that inactivate β-lactam antibiotics, rendering bacteria resistant to them. Asp-120 is fully conserved in all metallo-β-lactamases and is central to catalysis.
Bennett, Brian +5 more
core +1 more source
Molecular characterization of carbapenem-resistant and metallo-β-lactamase-producing Pseudomonas aeruginosa isolated from blood cultures from children and teenagers with cancer [PDF]
, 2010 INTRODUCTION: The objective of this study was to evaluate the prevalence and dissemination of carbapenem-resistant and metallo-β-lactamase-producing Pseudomonas aeruginosa isolated from blood-stream samples (2000-2005) that were collected from patients ...
Fernandes, Thaís Ávila +3 more
core +3 more sources
Revista da Sociedade Brasileira de Medicina TropicalCarbapenem-resistant Pseudomonas aeruginosa (CRPA) has been considered a major cause of infection and mortality in burn patients, especially in developing countries such as Iran. One of the most common mechanisms of carbapenem resistance is production of
Fereshteh Jabalameli +3 more
doaj +1 more source
Brazilian Journal of Infectious Diseases, 2010 This study evaluated the clonal spread of carbapenem-resistant P. aeruginosa producing SPM-1 type metallo-β-lactamase (MBL), at the university hospital of Florianópolis, Santa Catarina, Brazil, compared to an epidemic clone previously reported, as well ...
Mara Cristina Scheffer +4 more
doaj +1 more source
Clinical and veterinary trypanocidal benzoxaboroles target CPSF3 [PDF]
, 2018 African trypanosomes cause lethal and neglected tropical diseases, known as sleeping sickness in humans and nagana in animals. Current therapies are limited, but fortunately, promising therapies are in advanced clinical and veterinary development ...
Akama +17 more
core +3 more sources
MicrobiologyOpen, Volume 15, Issue 1, February 2026.Iranian clinical Stenotrophomonas maltophilia isolates showed high susceptibility to trimethoprim/sulfamethoxazole, minocycline, and levofloxacin, but marked resistance to ceftazidime and ticarcillin‐clavulanate, alongside widespread biofilm production and resistance genes.
Haneen Fadhil Jasim +6 more
wiley +1 more source
Resistance of Gram-Negative Bacteria to Cefepime-Enmetazobactam: A Systematic Review
PathogensCefepime-enmetazobactam is a novel β-lactam/β-lactamase inhibitor combination showing good activity against multidrug-resistant (MDR) Gram-negative bacteria producing a variety of β-lactamases.
Matthew E. Falagas +4 more
doaj +1 more source
Carbapenemase-producing Enterobacteriaceae in hospital wastewater:a reservoir that may be unrelated to clinical isolates [star] [PDF]
, 2016 Summary Background: Carbapenemase-producing Enterobacteriaceae (CPE) are an emerging infection control problem in hospitals worldwide. Identifying carriers can help reduce potential spread and infections.
Cheesbrough, John +8 more
core +1 more source