Results 91 to 100 of about 905,435 (191)

Metallo-β-lactamase and genetic diversity of Pseudomonas aeruginosa in intensive care units in Campo Grande, MS, Brazil

Brazilian Journal of Infectious Diseases
Infection by Pseudomonas aeruginosa has spread worldwide, with limited options for treatment. The purpose of this study was to investigate metallo-β-lactamase-producing P.
Ana Claudia Souza Rodrigues, Marilene Rodrigues Chang, Gabriela Dorn Nóbrega, Mayara Souza Rodrigues, Nadia Cristina Pereira Carvalho, Beatriz Garcia Gomes, Dênio Lopes de Almeida, Karyne Rangel Carvalho, Marise Dutra Asensi   +8 more
doaj   +1 more source

Genomic Insights Into Antimicrobial Resistance and Virulence of Enterococcus avium Strains From Bovine Mastitis in Some Selected Dairy Farms of Bangladesh

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
The graphical abstract outlines that samples from milk, faeces and soil were tested for Enterococcus avium using culture, PCR and genome sequencing.2. Overall, prevalence of E. avium was 56.3%, and 93.5% of isolates were multidrug‐resistant.3. Genomic analysis revealed six ARGs, 43–45 VFGs and 4–6 bacteriocins.4.
Monira Rahaman, Md. Morshedur Rahman, Kh. Yeashir Arafat, Md. Abu Ahsan Gilman, Naim Siddique, Taniya Sultana, Ziban Chandra Das, Anup Kumar Talukder, Tofazzal Islam, A. N. M. Aminoor Rahman, M. Nazmul Hoque   +10 more
wiley   +1 more source

Prevalence of metallo-β-lactamase-encoding genes among carbapenem-resistant Pseudomonas aeruginosa strains isolated from burn patients in Iran

Revista da Sociedade Brasileira de Medicina Tropical
Carbapenem-resistant Pseudomonas aeruginosa (CRPA) has been considered a major cause of infection and mortality in burn patients, especially in developing countries such as Iran. One of the most common mechanisms of carbapenem resistance is production of
Fereshteh Jabalameli, Elahe Taki, Mohammad Emaneini, Reza Beigverdi   +3 more
doaj   +1 more source

Identification and Genomic Analysis of the First Salmonella typhimurium Monophasic Variant 1,4,[5],12:i:‐ Isolate Harbouring a Chromosomally Integrated blaNDM‐5

Microbial Biotechnology, Volume 19, Issue 7, July 2026.
This study reports the first clinical isolate of the monophasic variant of Salmonella typhimurium (serotype 1,4,[5],12:i:‐) ST34 harbouring a chromosomally integrated blaNDM‐5. The ~11 kb resistance region is flanked by two directly oriented IS26 elements, forming an IS26‐composite transposon.
Shihan Zeng, Weilong Guo, Chengfeng Lin, Lianghui Peng, Jingjie Song   +4 more
wiley   +1 more source

Resistance of Gram-Negative Bacteria to Cefepime-Enmetazobactam: A Systematic Review

Pathogens
Cefepime-enmetazobactam is a novel β-lactam/β-lactamase inhibitor combination showing good activity against multidrug-resistant (MDR) Gram-negative bacteria producing a variety of β-lactamases.
Matthew E. Falagas, Laura T. Romanos, Dimitrios S. Kontogiannis, Katerina Tsiara, Stylianos A. Kakoullis   +4 more
doaj   +1 more source

Carbapenem-resistant Pseudomonas aeruginosa - clonal spread in Southern Brazil and in the State of Goiás

Brazilian Journal of Infectious Diseases, 2010
This study evaluated the clonal spread of carbapenem-resistant P. aeruginosa producing SPM-1 type metallo-β-lactamase (MBL), at the university hospital of Florianópolis, Santa Catarina, Brazil, compared to an epidemic clone previously reported, as well ...
Mara Cristina Scheffer, Ana Cristina Gales, Afonso Luis Barth, José Rodrigues do Carmo Filho, Libera Maria Dalla-Costa   +4 more
doaj   +1 more source

Small molecule Metallo-β-Lactamase inhibitors

, 2017
Several mechanisms have been discovered by which bacteria can acquire resistance against antibiotics. The most common and troubling resistance mechanism originates from the production of metallo-β-lactamases (4).
Gebreslasie, Kflom Yemane
core   +2 more sources

Screening of Heavy Metals Tolerance among Beta-Lactamase Producing Bacteria from Contaminated Soil and Waste Water of Some Abattoirs in Adamawa State

UMYU Journal of Microbiology Research
Bacterial adaptability enables them to tolerate various stresses, including those from antibiotics and heavy metals.  This study aims to investigate the tolerance to heavy metals, as well as the production of beta-lactamase and metallo-beta-lactamase ...
Ja’afaru, M. I., Bristone J Pola, Pukuma, M. S., Emmanuel Ijabani   +3 more
doaj   +1 more source

Approachable Synthetic Methodologies for Second-Generation β-Lactamase Inhibitors: A Review

Pharmaceuticals
Some antibiotics that are frequently employed are β-lactams. In light of the hydrolytic process of β-lactamase, found in Gram-negative bacteria, inhibitors of β-lactamase (BLIs) have been produced.
Noor Fatima, Shehla Khalid, Nasir Rasool, Muhammad Imran, Bushra Parveen, Aqsa Kanwal, Marius Irimie, Codrut Ioan Ciurea   +7 more
doaj   +1 more source

Antibiotic sensitization using biphenyl tetrazoles as potent inhibitors of Bacteroides fragilis metallo-β-lactamase [PDF]

, 1998
Background: High level resistance to carbapenem antibiotics in gram negative bacteria such as Bacteroides fragilis is caused, in part, by expression of a wide-spectrum metallo-β-lactamase that hydrolyzes the drug to an inactive form. Co-administration of
Olson, Steven H., Sundelof, Jon G., Cleary, Kelly A., Grant, Stephan K., Hammond, Gail G., Fitzgerald, Paula M.D., Kozarich, John W., May, Walter J., Toney, Jeffrey H., Grover-Sharma, Nandini, Vanderwall, Dana E., Wu, Joseph K., Pompliano, David L.   +12 more
core   +1 more source