Results 91 to 100 of about 19,930 (199)

Extended-spectrum ß-lactamase and carbapenemaseproducing Aeromonas species in wild animals from Portugal [PDF]

, 2014
Aeromonas are Gram-negative, facultative-anaerobic, non-spore-forming, glucose-fermenting, oxidase- and catalase-positive rods (Martin-Carnahan and Joseph 2005).
Avison, Bauer, Ceylan, CLSI, Evangelista-barreto, Fontes, Hayes, Henriques, Janda, Janda, Libisch, Martin-carnahan, Martínez-murcia, Martínez-murcia, Neuwirth, Parker, Pearson, Reith, Saavedra, Saavedra, Saavedra, Seshadri, Soler, Turutoglu, Walsh, Yáñez   +25 more
core   +1 more source

bZIP63.5 Regulates a Zinc‐Finger Mediated Detoxification Network in Trichoderma Harzianum for Enhanced Biocontrol of Alternaria alternata

Microbial Biotechnology, Volume 19, Issue 3, March 2026.
The bZIP63.5 transcription factor, activated by Alternaria alternata stress, directly upregulates zinc‐finger transcription factors (Zn2CyS6 and C2H2 types), which in turn enhance the expression of downstream detoxification and defence‐related genes, collectively improving the biocontrol efficacy of Trichoderma harzianum.
Yongfeng Yang, Huifang Zhang, Bin Liu, Jing Han, Ning Kong, Jingwen Gao, Zhihua Liu   +6 more
wiley   +1 more source

Redirecting pantoprazole as a metallo-beta-lactamase inhibitor in carbapenem-resistant Klebsiella pneumoniae

Frontiers in Pharmacology
The development of resistance to carbapenems in Klebsiella pneumoniae due to the production of metallo-β-lactamases (MBLs) is a critical public health problem because carbapenems are the last-resort drugs used for treating severe infections of extended ...
Wesam H. Abdulaal, Nabil A. Alhakamy, Nabil A. Alhakamy, Nabil A. Alhakamy, Amer H. Asseri, Amer H. Asseri, Mohamed F. Radwan, Tarek S. Ibrahim, Solomon Z. Okbazghi, Hisham A. Abbas, Basem Mansour, Aly A. Shoun, Wael A. H. Hegazy, Wael A. H. Hegazy, Mahmoud Saad Abdel-Halim   +14 more
doaj   +1 more source

Antimicrobial Resistance in Salmonella Across Aquaculture, Seafood and Related Aquatic Environments: A Scoping Review With Exploratory Textual Analysis

Reviews in Aquaculture, Volume 18, Issue 2, March 2026.
This scoping review with textual analysis maps antimicrobial resistance in Salmonella across aquaculture, seafood, and related aquatic environments. Across 93 studies, recurrent MDR patterns suggest sentinel serotypes (S. Typhimurium, S. Newport) and a minimal antimicrobial susceptibility testing (AST) panel to guide matrix‐stratified One Health ...
Cristiane Coimbra de Paula, Yuri Duarte Porto, Vinícius Silva Castro, Érica do Carmo Dias Matos, Adelino Cunha‐Neto, Ricardo César Tavares Carvalho, Luciana Kimie Savay‐da‐Silva, Eduardo Eustáquio de Souza Figueiredo, Tathiana Ferguson Motheo   +8 more
wiley   +1 more source

Genome of the carbapenemase-producing clinical isolate Elizabethkingia miricola EM_CHUV and comparative genomics with Elizabethkingia meningoseptica and Elizabethkingia anophelis: evidence for intrinsic multidrug resistance trait of emerging pathogens. [PDF]

, 2017
Elizabethkingia miricola is a Gram-negative non-fermenting rod emerging as a life-threatening human pathogen. The multidrug-resistant (MDR) carbapenemase-producing clinical isolate E.
Bertelli, C., Diene, S.M., Eckert, P., Greub, G., Opota, O., Prod'hom, G.   +5 more
core   +1 more source

Pharmacokinetics of Aztreonam–Avibactam After Single‐ and Multiple‐Dose Administration: A Phase 1, Open‐Label Study in Healthy Chinese Participants and Ethnic Comparison with Non‐Chinese Participants

Clinical Pharmacology in Drug Development, Volume 15, Issue 2, February 2026.
ABSTRACT Combined treatment with aztreonam (an established intravenous antibiotic) and avibactam (a β‐lactamase inhibitor) has the potential to address the unmet need for safe and effective agents to combat infections caused by Gram‐negative bacteria producing metallo β‐lactamases (MBLs).
Jingjing Wang, Jinjie He, Jufang Wu, Jing Zhang, Ying Ma, Xiaoqing Ren, Hua Wei, Chunye Zhang, Hua Zhu, Susan R. Raber, Shuangchen Cong   +10 more
wiley   +1 more source

Metallo-β-lactamase and genetic diversity of Pseudomonas aeruginosa in intensive care units in Campo Grande, MS, Brazil

Brazilian Journal of Infectious Diseases
Infection by Pseudomonas aeruginosa has spread worldwide, with limited options for treatment. The purpose of this study was to investigate metallo-β-lactamase-producing P.
Ana Claudia Souza Rodrigues, Marilene Rodrigues Chang, Gabriela Dorn Nóbrega, Mayara Souza Rodrigues, Nadia Cristina Pereira Carvalho, Beatriz Garcia Gomes, Dênio Lopes de Almeida, Karyne Rangel Carvalho, Marise Dutra Asensi   +8 more
doaj   +1 more source

Validation of Hexaplex Recombinase Polymerase Amplification Assay for the Detection of Carbapenemase Genes in Klebsiella pneumoniae Isolates From Pediatric Inpatients

Journal of Clinical Laboratory Analysis, Volume 40, Issue 4, February 2026.
A novel hexaplex recombinase polymerase amplification (RPA) method was developed to rapidly and accurately detect five key carbapenemase genes and a Klebsiella pneumoniae‐specific target in a single reaction. This makes it an effective tool for CRKP detection in resource‐constrained environments.
Suthawan Mutitanon, Nuntaree Chaichanawongsaroj   +1 more
wiley   +1 more source

Prevalence of Clinically Isolated Metallo-beta-lactamase-producing Pseudomonas aeruginosa, Coding Genes, and Possible Risk Factors in Iran [PDF]

, 2018
Background & Objective: The spread of carbapenem-resistant Pseudomonas aeruginosa is a global concern. Metallo-beta-lactamase (MBL) enzymes cause extensive drug resistance among Gram-negative bacteria.
Ghasemian, Abdolmajid., Nojoomi, Farshad., Rajabi Vardanjani, Hassan., Salimian Rizi, Kobra.   +3 more
core  

Conformational Changes in the Metallo-β-lactamase ImiS During the Catalytic Reaction: An EPR Spectrokinetic Study of Co(II)-Spin Label Interactions [PDF]

, 2008
Metallo-β-lactamases are responsible for conferring antibiotic resistance on certain pathogenic bacteria. In consequence, the search for inhibitors that may be useful in combating antibiotic resistance has fueled much study of the active sites of these ...
Bennett, Brian, Crowder, Michael W., Hu, Zhenxin, Sharma, Narayan   +3 more
core   +2 more sources