Results 71 to 80 of about 19,930 (199)

Phage Therapy as an Alternative Strategy Against Pseudomonas aeruginosa: A Narrative Review of Preclinical and Clinical Evidence

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Phage therapy shows promising efficacy against MDR, XDR, and PDR Pseudomonas aeruginosa infections across different models and administration routes. Evidence highlights reduced mortality, bacterial clearance, and synergy with antibiotics, while emphasizing the need for standardized protocols and advanced delivery systems to support clinical ...
Gustavo Aparecido da Cunha, Raine Piva Amaral, Ana Luisa Cauvila dos Santos, Bárbara Rafaela Ferreira Aio, Maria Fernanda Romboli Durante, Luiz Cosme Cotta Malaquias, Gabriel Magno de Freitas Almeida, Luiz Felipe Leomil Coelho   +7 more
wiley   +1 more source

Additional file 1: Table S1. of Structure, Genetics and Worldwide Spread of New Delhi Metallo-β-lactamase (NDM): a threat to public health

, 2017
Worldwide distribution of NDM producing bacteria, as per articles available on PubMed database in the time period of Dec 2013 to Feb 2017. (PDF 136Â kb)
Khan, Asad, Maryam, Lubna, Zarrilli, Raffaele   +2 more
openaire   +1 more source

Rapid detection of carbapenemase-producing Enterobacteriaceae. [PDF]

, 2012
To rapidly identify carbapenemase producers in Enterobacteriaceae, we developed the Carba NP test. The test uses isolated bacterial colonies and is based on in vitro hydrolysis of a carbapenem, imipenem.
Dortet, L, Nordmann, P, Poirel, L
core   +1 more source

Phenotypic and Genotypic Study of Antibiotic Resistance blaPER‐1, blaVEB, and blaSHV‐1 Genes in Clinical Isolates of Pseudomonas aeruginosa

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Pseudomonas aeruginosa is a non‐fermentative, opportunistic Gram‐negative bacterium that causes 10%–15% of nosocomial and burn wound infections worldwide. This bacterium is resistant to various antibiotics through multiple mechanisms, including acquisition of resistance genes.
Milad Gholampour Matin, Reza Shapouri, Mohammadreza Nahaei, Mojtaba Mohammadi Roknabadi, Rasoul Shokri   +4 more
wiley   +1 more source

Inhibitory Potential of Polyclonal Camel Antibodies against New Delhi Metallo-β-lactamase-1 (NDM-1)

Molecules, 2020
New Delhi Metallo-β-lactamase-1 (NDM-1) is the most prevalent type of metallo-β-lactamase, able to hydrolyze almost all antibiotics of the β-lactam group, leading to multidrug-resistant bacteria.
Rahma Ben Abderrazek, Sarra Chammam, Ayoub Ksouri, Mariagrazia Perilli, Sayda Dhaouadi, Ines Mdini, Zakaria Benlasfar, Gianfranco Amicosante, Balkiss Bouhaouala-Zahar, Alessandra Piccirilli   +9 more
doaj   +1 more source

Evidence for a Dinuclear Active Site in the Metallo-β-lactamase BcII with Substoichiometric Co(II): A New Model for Uptake [PDF]

, 2007
Metallo-β-lactamases are zinc-dependent enzymes that constitute one of the main resistance mechanisms to β-lactam antibiotics. Metallo-β-lactamases have been characterized both in mono- and dimetallic forms.
Bennett, Brian, Kowalski, Jason M., Llarrull, Leticia l., Tioni, Mariana F., Vila, Alejandro J.   +4 more
core   +1 more source

Metalloids: Semi as Metals yet Full of Antimicrobial Potential

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Metalloids such as boron (B), silicon (Si), germanium (Ge), arsenic (As), antimony (Sb), and tellurium (Te) bridge metals and non‐metals, displaying unique chemical versatility. Recent research highlights their diverse antimicrobial and therapeutic potentials, from natural products to synthetic organic and organometallic molcules, underscoring renewed ...
Kevin Böhm, Muhammad Jawad Nasim, Claus Jacob   +2 more
wiley   +1 more source

Emergence and Polyclonal Dissemination of blaNDM-7–Carrying InX3 Plasmid in Enterobacter cloacae Complex, France, 2021–2023

Emerging Infectious Diseases
Among 3,367 New Delhi metallo-β-lactamase–producing Enterobacterales isolates collected in France during 2021–2023, we found the blaNDM-7 gene systematically localized on 2 closely related InX3 plasmids known to harbor antimicrobial resistance and ...
Ines Rezzoug, Delphine Girlich, Aurelien Birer, Richard Bonnet, Josephine Poiraud, Pierre Bogaerts, Cécile Emeraud, Laurent Dortet   +7 more
doaj   +1 more source

Metallo-β-lactamase and genetic diversity of Pseudomonas aeruginosa in intensive care units in Campo Grande, MS, Brazil

Brazilian Journal of Infectious Diseases, 2011
Infection by Pseudomonas aeruginosa has spread worldwide, with limited options for treatment. The purpose of this study was to investigate metallo-β-lactamase-producing P.
Ana Claudia Souza Rodrigues, M.D., Marilene Rodrigues Chang, Ph.D., Gabriela Dorn Nóbrega, Mayara Souza Rodrigues, Nadia Cristina Pereira Carvalho, Beatriz Garcia Gomes, Dênio Lopes de Almeida, Karyne Rangel Carvalho, M.D., Marise Dutra Asensi, Ph.D.   +8 more
doaj   +1 more source

Mechanisms involved in acquisition of blaNDM genes by IncA/C2 and IncFIIY plasmids [PDF]

, 2016
blaNDM genes confer carbapenem resistance and have been identified on transferable plasmids belonging to different incompatibility (Inc) groups. Here we present the complete sequences of four plasmids carrying a blaNDM gene, pKP1-NDM-1, pEC2-NDM-3, pECL3-
Alikhan, Nabil-Fareed, Beatson, Scott A., Forde, Brian M., Partridge, Sally R., Paterson, David L., Petty, Nicola K., Sartor, Anna L., Schembri, Mark A., Sidjabat, Hanna E., Wailan, Alexander M., Walsh, Timothy R., Williamson, Deborah A., Yam, Wan Keat   +12 more
core   +2 more sources