Results 71 to 80 of about 905,435 (191)
Brazilian Journal of Infectious Diseases, 2011 Infection by Pseudomonas aeruginosa has spread worldwide, with limited options for treatment. The purpose of this study was to investigate metallo-β-lactamase-producing P.
Ana Claudia Souza Rodrigues, M.D. +8 more
doaj +1 more source
ChemBioChem, Volume 27, Issue 16, 27 August 2026.Approved zinc‐binding drugs and newly synthesized HisPyr ligands were evaluated as adjuvants to meropenem against metallo‐β‐lactamase‐producing Klebsiella pneumoniae. Chlorpropamide and D‐penicillamine restored meropenem activity against the VIM‐1‐producing strain, while computational analyses supported interactions with the enzyme's binuclear zinc ...
Chiara Ragusa +6 more
wiley +1 more source
Estudo de isolados clínicos de Pseudomonas aeruginosa multirresistentes e produtores de metalo-ß-lactamases [PDF]
, 2011 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biotecnologia e Biociências, Florianópolis, 2011Nas últimas duas décadas, índices crescentes de resistência têm minado a eficácia
Guarneri, Rômulo
core
, 2023 β-lactams are the most prescribed class of antibiotics due to their potent, broad-spectrum antimicrobial activities. However, alarming rates of antimicrobial resistance now threaten the clinical relevance of these drugs, especially for the carbapenem ...
Sanil D. Singh (7323659) +16 more
core +1 more source
Plasmid-Borne AFM Alleles in Pseudomonas aeruginosa Clinical Isolates from China
Microbiology Spectrum, 2022 Carbapenem-resistant Pseudomonas aeruginosa (CRPA) is a pathogen of global concern due to the fact that therapeutic drugs are limited. Metallo-β-lactamase (MBL)-producing P. aeruginosa has become a critical part of CRPA.
Minhua Chen +7 more
doaj +1 more source
Clinical Case Reports, Volume 14, Issue 8, August 2026.ABSTRACT Pan‐drug resistant Klebsiella pneumoniae is a major therapeutic challenge, particularly when standard last‐line agents are unavailable or contraindicated. We report a 45‐year‐old man with multifocal osteomyelitis and persistent purulent wound discharge despite broad‐spectrum antibiotics, repeated debridement, and two sequential amputations ...
Ali Akbar Heydari +2 more
wiley +1 more source
MicrobiologyOpen, Volume 15, Issue 4, August 2026.Graphical Abstract of the Experimental Workflow for CRAB Isolate Characterization. ABSTRACT Carbapenem‐resistant Acinetobacter baumannii (CRAB) has been designated a top‐priority critical pathogen by the World Health Organization, and the CDC has also classified it as a serious and immediate public health threat. The Cross‐sectional study was conducted
Hafsa Waseem +5 more
wiley +1 more source
, 2019 Infections with Pseudomonas aeruginosa isolates producing Metallo- β- Lactamase (MBL) is a serious worldwide infections. It is associated with, higher mortality rates, more severe disease implicated and with a higher incidence of invasive disease than ...
Chateen I. Ali Pambuk +2 more
core +1 more source
Проблемы особо опасных инфекций, 2012 The set of oligonucleotide primers was designed to identify β-lactam-resitance determinats in isolates of pathogenic Burkholderia using PCR. Simultaneously identified was certain molecular class of detected β-lactamases.
A. V. Romanova +3 more
doaj +1 more source
Genomic Epidemiology of Multidrug‐Resistant Clinical Klebsiella pneumoniae From Pakistan
MicrobiologyOpen, Volume 15, Issue 4, August 2026.Study design and bioinformatics workflow. Cohort selection and uniform workflow. ABSTRACT Background Antimicrobial‐resistant Klebsiella pneumoniae is a major clinical threat in Pakistan and the wider South Asian region, where genomic surveillance remains limited. We analyzed 122 publicly available human clinical K.
Hakeem Zada +6 more
wiley +1 more source