Results 61 to 70 of about 12,806 (157)

Metalloids: Semi as Metals yet Full of Antimicrobial Potential

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Metalloids such as boron (B), silicon (Si), germanium (Ge), arsenic (As), antimony (Sb), and tellurium (Te) bridge metals and non‐metals, displaying unique chemical versatility. Recent research highlights their diverse antimicrobial and therapeutic potentials, from natural products to synthetic organic and organometallic molcules, underscoring renewed ...
Kevin Böhm, Muhammad Jawad Nasim, Claus Jacob   +2 more
wiley   +1 more source

Evolution of Point‐of‐Care Nucleic Acid Testing: From Amplification Chemistry to Intelligent and Data‐Driven Systems for Public Health

Aggregate, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in integrated point‐of‐care testing (POCT) systems for public health, encompassing isothermal nucleic acid amplification, CRISPR‐based signal amplification, device integration, and chemometric/artificial intelligence‐assisted data interpretation, with applications in infectious disease surveillance, food and ...
Yan Du, Jiaqi Li, Jinghong Li
wiley   +1 more source

Redirecting pantoprazole as a metallo-beta-lactamase inhibitor in carbapenem-resistant Klebsiella pneumoniae

Frontiers in Pharmacology
The development of resistance to carbapenems in Klebsiella pneumoniae due to the production of metallo-β-lactamases (MBLs) is a critical public health problem because carbapenems are the last-resort drugs used for treating severe infections of extended ...
Wesam H. Abdulaal, Nabil A. Alhakamy, Nabil A. Alhakamy, Nabil A. Alhakamy, Amer H. Asseri, Amer H. Asseri, Mohamed F. Radwan, Tarek S. Ibrahim, Solomon Z. Okbazghi, Hisham A. Abbas, Basem Mansour, Aly A. Shoun, Wael A. H. Hegazy, Wael A. H. Hegazy, Mahmoud Saad Abdel-Halim   +14 more
doaj   +1 more source

Microbial Etiology and Antimicrobial Resistance in Pneumonia Among Hospitalized Patients in Kazakhstan: A Systematic Review and Single‐Arm Meta‐Analysis of Prevalence Data

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Pneumonia is an inflammatory condition of the lower respiratory tract, commonly caused by infection and associated with substantial morbidity and healthcare utilization. The burden of pneumonia on healthcare is exacerbated by limited data on pathogenic causes and associated antimicrobial resistance (AMR). Here, we conducted
Radmir Sarsenov, Maxim Solomadin, Alyona Lavrinenko, Vyacheslav Beloussov, Vitaliy Strochkov, Shynggys Orkara, Nurlan Sandybayev, Sergey Yegorov   +7 more
wiley   +1 more source

The Evaluation of Machine Learning Models Using Matrix‐Assisted Laser Desorption/Ionization Time‐of‐Flight Mass Spectrometry (MALDI–TOF–MS) Spectra for the Prediction of Antibiotic Resistance in Klebsiella pneumoniae

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
Machine learning models developed from matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry spectra can rapidly predict antimicrobial resistance in Klebsiella pneumoniae. By transforming routine spectral data into accurate resistance profiles within minutes, this approach could reduce diagnostic delays and support earlier ...
Stephen Mark Edward Fordham
wiley   +1 more source

Metallo-β-lactamase and genetic diversity of Pseudomonas aeruginosa in intensive care units in Campo Grande, MS, Brazil

Brazilian Journal of Infectious Diseases
Infection by Pseudomonas aeruginosa has spread worldwide, with limited options for treatment. The purpose of this study was to investigate metallo-β-lactamase-producing P.
Ana Claudia Souza Rodrigues, Marilene Rodrigues Chang, Gabriela Dorn Nóbrega, Mayara Souza Rodrigues, Nadia Cristina Pereira Carvalho, Beatriz Garcia Gomes, Dênio Lopes de Almeida, Karyne Rangel Carvalho, Marise Dutra Asensi   +8 more
doaj   +1 more source

Antimicrobial Effect of Spices and Their Phytochemicals: A Novel Approach to Overcoming Antibiotic Resistance

MedComm, Volume 7, Issue 4, April 2026.
This graphical abstract shows the antibacterial potential of phytochemicals from 15 spices, showcasing key compounds, their extraction methods, and mechanisms of action. It highlights membrane disruption, ROS generation, enzyme inhibition, and biofilm prevention as core antibacterial pathways.
Hettiyahandi Binodh De Silva, Yanqi Dai, Shervanthi Homer‐Vanniasinkam, Mohan Edirisinghe   +3 more
wiley   +1 more source

bZIP63.5 Regulates a Zinc‐Finger Mediated Detoxification Network in Trichoderma Harzianum for Enhanced Biocontrol of Alternaria alternata

Microbial Biotechnology, Volume 19, Issue 3, March 2026.
The bZIP63.5 transcription factor, activated by Alternaria alternata stress, directly upregulates zinc‐finger transcription factors (Zn2CyS6 and C2H2 types), which in turn enhance the expression of downstream detoxification and defence‐related genes, collectively improving the biocontrol efficacy of Trichoderma harzianum.
Yongfeng Yang, Huifang Zhang, Bin Liu, Jing Han, Ning Kong, Jingwen Gao, Zhihua Liu   +6 more
wiley   +1 more source

Antimicrobial Resistance in Salmonella Across Aquaculture, Seafood and Related Aquatic Environments: A Scoping Review With Exploratory Textual Analysis

Reviews in Aquaculture, Volume 18, Issue 2, March 2026.
This scoping review with textual analysis maps antimicrobial resistance in Salmonella across aquaculture, seafood, and related aquatic environments. Across 93 studies, recurrent MDR patterns suggest sentinel serotypes (S. Typhimurium, S. Newport) and a minimal antimicrobial susceptibility testing (AST) panel to guide matrix‐stratified One Health ...
Cristiane Coimbra de Paula, Yuri Duarte Porto, Vinícius Silva Castro, Érica do Carmo Dias Matos, Adelino Cunha‐Neto, Ricardo César Tavares Carvalho, Luciana Kimie Savay‐da‐Silva, Eduardo Eustáquio de Souza Figueiredo, Tathiana Ferguson Motheo   +8 more
wiley   +1 more source

Prevalence of metallo-β-lactamase-encoding genes among carbapenem-resistant Pseudomonas aeruginosa strains isolated from burn patients in Iran

Revista da Sociedade Brasileira de Medicina Tropical
Carbapenem-resistant Pseudomonas aeruginosa (CRPA) has been considered a major cause of infection and mortality in burn patients, especially in developing countries such as Iran. One of the most common mechanisms of carbapenem resistance is production of
Fereshteh Jabalameli, Elahe Taki, Mohammad Emaneini, Reza Beigverdi   +3 more
doaj   +1 more source