Results 61 to 70 of about 19,930 (199)

Evaluation of Metallo-β-Lactamase-Production and Carriage of bla-_VIM Genes in Pseudomonas aeruginosa Isolated from Burn Wound Infections in Isfahan [PDF]

, 2016
Background: Metallo-β-lactamase-production among Gram-negative bacteria, including Pseudomonas aeruginosa, has become a challenge for treatment of infections due to these resistant bacteria. Objectives: The aim of the current study was to evaluate the
Firoozeh, F., Pourbabaee, M., Saffari, M., Zibaei, M.   +3 more
core  

Plasmid-mediated novel blaNDM-17 gene encoding a Carbapenemase with enhanced activity in a sequence type 48 Escherichia coli strain [PDF]

, 2017
Carbapenem-resistant Enterobacteriaceae (CRE) have spread worldwide, leaving very few treatment options available. New Delhi metallo-beta-lactamase (NDM) is the main carbapenemase mediating CRE resistance and is of increasing concern.
Li, Jiyun, Liu, Dejun, Liu, Zhihai, Shen, Jianzhong, Shen, Zhangqi, Walsh, Timothy Rutland, Wang, Yang, Yao, Hong, Yin, Wenjuan, Zhang, Rongmin   +9 more
core   +2 more sources

Genomic Insights Into Carbapenem‐Resistant Klebsiella pneumoniae in Pediatric Bloodstream Infections in Zhejiang, China (2019–2024)

Journal of Clinical Laboratory Analysis, EarlyView.
The primary mechanism of carbapenem resistance identified in pediatric CRKP‐BSI strains was the production of Class B metalloenzymes. We report, for the first time, an outbreak of bloodstream infections in a neonatal ward caused by the dissemination of NDM‐1‐producing ST25 K. pneumoniae.
Mingming Zhou, Xiucai Zhang, Zhenjie Chen, Chao Fang, Shixing Liu, Jintao Xia, Yining Zhao, Chenmei Zhang, Hongqiang Shen   +8 more
wiley   +1 more source

In vitro activity of aztreonam in combination with relebactam against gram-negative pathogens producing various serine and metallo-β-lactamases

Journal of Global Antimicrobial Resistance
Objectives: Infections caused by carbapenemase-producing Gram-negative pathogens have become a significant global public health challenge due to limited treatment options.
Kengo Hayashi, Masahiro Suzuki, Yoshikazu Ishii, Yasufumi Matsumura, Kazuaki Matsumoto, Sho Saito, Yohei Doi   +6 more
doaj   +1 more source

MOESM1 of Whole genome sequencing uncovers a novel IND-16 metallo-β-lactamase from an extensively drug-resistant Chryseobacterium indologenes strain J31

, 2016
Additional files 1: Table S1. Antimicrobial susceptibility profiles of C. indologenes J31.
Tingting Wang, Xiawei Jiang, Chunyan Feng, Li, Ang, Huihui Dong, Shaoqiang Wu, Beiwen Zheng   +6 more
openaire   +1 more source

Membrane anchoring stabilizes and favors secretion of New Delhi metallo-β-lactamase [PDF]

, 2015
Carbapenems, 'last-resort' β-lactam antibiotics, are inactivated by zinc-dependent metallo-β-lactamases (MBLs). The host innate immune response withholds nutrient metal ions from microbial pathogens by releasing metal-chelating proteins such as ...
A Kovacs-Simon, A Rokney, Alejandro J Vila, B Johne, BD Corbin, C Rumbo, C Schwechheimer, C Zhang, CA Schneider, D King, Elizabeth M Nolan, G Fiorilli, G Patel, G Periyannan, Guillermo Bahr, HJ Bootsma, J Morán-Barrio, JE Irazoqui, JM Bomberger, JM González, JM González, K Hede, KH Choi, KP Haley, L Dortet, L Poirel, LB Randall, Lisandro J González, LJ González, M Cerasi, M Hernandez Valladares, M Hussain, M Park, MB Brophy, ME Kovach, MF Haurat, MI Hood, MR Meini, MS Aschtgen, MW Crowder, N Selevsek, NC Kesty, P Marchiaro, P Ravasi, PD Veith, PS Borra, R Gläser, R Kitagawa, Robert A Bonomo, S Devos, S Santos, S Tottey, S Wommer, TA Murphy, Toshiki G Nakashige, TR Walsh, TR Walsh, V Schaar, V Schaar, VG Pederick, X Chen, Y Kim, Y Luo, Z Hu   +63 more
core   +3 more sources

Performance of the BioFire FilmArray Pneumonia Panel Plus Compared to Standard Microbiology in Lung Transplant Donor and Recipient Samples: A Prospective Cohort Study

Transplant Infectious Disease, EarlyView.
A prospective study demonstrating that the BioFire Pneumonia Panel Plus shows substantial concordance with culture in donor samples and moderate concordance in recipient samples, supporting its potential role in guiding perioperative antibiotic prophylaxis in lung transplantation.
Andrea Lombardi, Giulia Renisi, Lorenzo Rosso, Letizia Morlacchi, Jacopo Fumagalli, Lisa Cariani, Ilaria Righi, Valeria Rossetti, Arianna Liparoti, Cecilia Azzarà, Davide Mangioni, Laura Alagna, Paola Saltini, Maria Francesca Liporace, Chiara Abbruzzese, Annapaola Callegaro, Francesco Blasi, Giacomo Grasselli, Mario Nosotti, Alessandra Bandera   +19 more
wiley   +1 more source

Plasmid Profile Analysis and bla VIM Gene Detection of Metalo β-lactamase (MBL) Producing Pseudomonas aeruginosa Isolates from Clinical Samples [PDF]

Journal of Clinical and Diagnostic Research, 2014
Introduction: Pseudomonas aeruginosa is a frequent colonizer of hospitalized patients. They are responsible for serious infections such as meningitis, urological infections, septicemia and pneumonia.
Jayanthi S., Jeya M.
doaj   +1 more source

In Vitro Susceptibility of Aztreonam-Vaborbactam, Aztreonam-Relebactam and Aztreonam-Avibactam Associations against Metallo-β-Lactamase-Producing Gram-Negative Bacteria

Antibiotics, 2023
Background: Despite the availability of new options (ceftazidime-avibactam, imipenem-relebactam, meropenem-vaborbactam and cefiderocol), it is still very difficult to treat infections caused by metallo-β-lactamase (MBLs)-producers resistant to aztreonam.
Cécile Emeraud, Sandrine Bernabeu, Laurent Dortet   +2 more
doaj   +1 more source

MOESM2 of Whole genome sequencing uncovers a novel IND-16 metallo-β-lactamase from an extensively drug-resistant Chryseobacterium indologenes strain J31

, 2016
Additional files 2: Table S2. Numerous antibiotic resistance genes predicted in the C. indologenes J31 genome.
Tingting Wang, Xiawei Jiang, Chunyan Feng, Li, Ang, Huihui Dong, Shaoqiang Wu, Beiwen Zheng   +6 more
openaire   +1 more source