Results 41 to 50 of about 12,806 (157)

Phage Therapy as an Alternative Strategy Against Pseudomonas aeruginosa: A Narrative Review of Preclinical and Clinical Evidence

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Phage therapy shows promising efficacy against MDR, XDR, and PDR Pseudomonas aeruginosa infections across different models and administration routes. Evidence highlights reduced mortality, bacterial clearance, and synergy with antibiotics, while emphasizing the need for standardized protocols and advanced delivery systems to support clinical ...
Gustavo Aparecido da Cunha, Raine Piva Amaral, Ana Luisa Cauvila dos Santos, Bárbara Rafaela Ferreira Aio, Maria Fernanda Romboli Durante, Luiz Cosme Cotta Malaquias, Gabriel Magno de Freitas Almeida, Luiz Felipe Leomil Coelho   +7 more
wiley   +1 more source

MOESM6 of Whole genome sequencing uncovers a novel IND-16 metallo-β-lactamase from an extensively drug-resistant Chryseobacterium indologenes strain J31

, 2016
Additional files 6: Table S5. Four conjugative transposon gene clusters in the Chryseobacterium indologenes J31 genome.
Tingting Wang, Xiawei Jiang, Chunyan Feng, Li, Ang, Huihui Dong, Shaoqiang Wu, Beiwen Zheng   +6 more
openaire   +1 more source

Gut Microbiota Alterations Associated With Colonization by Multidrug‐Resistant Organisms in ICU Patients: First Systematic Review and Meta‐Analysis

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Microbiota profiling showed colonized critically ill patients had lower values of dominance/evenness (Simpson's index) and richness (Observed), reaching significantly lower values of information (mean difference in Shannon index = –1.18; 95% CI, –1.84 to –0.52; p < 0.001).
Andra‐Elena Goicea, Daniel‐Corneliu Leucuța, Constantin Bodolea   +2 more
wiley   +1 more source

In vitro activity of aztreonam in combination with relebactam against gram-negative pathogens producing various serine and metallo-β-lactamases

Journal of Global Antimicrobial Resistance
Objectives: Infections caused by carbapenemase-producing Gram-negative pathogens have become a significant global public health challenge due to limited treatment options.
Kengo Hayashi, Masahiro Suzuki, Yoshikazu Ishii, Yasufumi Matsumura, Kazuaki Matsumoto, Sho Saito, Yohei Doi   +6 more
doaj   +1 more source

MOESM7 of Whole genome sequencing uncovers a novel IND-16 metallo-β-lactamase from an extensively drug-resistant Chryseobacterium indologenes strain J31

, 2016
Additional files 7: Table S6. List of genome accessions used in whole-genome phylogenetic analysis.
Wang, Tingting, Jiang, Xiawei, Feng, Chunyan, Li, Ang, Dong, Huihui, Wu, Shaoqiang, Zheng, Beiwen   +6 more
openaire   +1 more source

In Vitro Susceptibility of Aztreonam-Vaborbactam, Aztreonam-Relebactam and Aztreonam-Avibactam Associations against Metallo-β-Lactamase-Producing Gram-Negative Bacteria

Antibiotics, 2023
Background: Despite the availability of new options (ceftazidime-avibactam, imipenem-relebactam, meropenem-vaborbactam and cefiderocol), it is still very difficult to treat infections caused by metallo-β-lactamase (MBLs)-producers resistant to aztreonam.
Cécile Emeraud, Sandrine Bernabeu, Laurent Dortet   +2 more
doaj   +1 more source

MOESM1 of Whole genome sequencing uncovers a novel IND-16 metallo-β-lactamase from an extensively drug-resistant Chryseobacterium indologenes strain J31

, 2016
Additional files 1: Table S1. Antimicrobial susceptibility profiles of C. indologenes J31.
Wang, Tingting, Jiang, Xiawei, Feng, Chunyan, Li, Ang, Dong, Huihui, Wu, Shaoqiang, Zheng, Beiwen   +6 more
openaire   +1 more source

Zwitterionic Penicillin‐Derived Sulfone Inhibitor for Combating β‐Lactamase‐Mediated Antibiotic Resistance

ChemMedChem, Volume 21, Issue 9, 14 May 2026.
Combining enhanced permeability strategies with (2‐pyridyl)methylene substitution in the sulbactam scaffold led to a novel β‐lactamase inhibitor to combat β‐lactamase‐mediated resistance to β‐lactam antibiotics. The studies presented highlight the potential of compound 3 as a next‐generation β‐lactamase inhibitor for combating infections caused by ...
Diana Rodríguez, Emilio Lence, Juan C. Vázquez‐Ucha, Alejandro Beceiro, Concepción González‐Bello   +4 more
wiley   +1 more source

Plasmid Profile Analysis and bla VIM Gene Detection of Metalo β-lactamase (MBL) Producing Pseudomonas aeruginosa Isolates from Clinical Samples [PDF]

Journal of Clinical and Diagnostic Research, 2014
Introduction: Pseudomonas aeruginosa is a frequent colonizer of hospitalized patients. They are responsible for serious infections such as meningitis, urological infections, septicemia and pneumonia.
Jayanthi S., Jeya M.
doaj   +1 more source

MOESM2 of Whole genome sequencing uncovers a novel IND-16 metallo-β-lactamase from an extensively drug-resistant Chryseobacterium indologenes strain J31

, 2016
Additional files 2: Table S2. Numerous antibiotic resistance genes predicted in the C. indologenes J31 genome.
Tingting Wang, Xiawei Jiang, Chunyan Feng, Li, Ang, Huihui Dong, Shaoqiang Wu, Beiwen Zheng   +6 more
openaire   +1 more source