Results 111 to 120 of about 19,930 (199)

Antibacterial Activity of Estragole From Ocimum tenuiflorum, and Tagetes lucida and Synergistic Effect With Meropenem and Tobramycin Against Multidrug‐ and Extensively Drug‐Resistant (MDR‐XDR) Gram‐Negative Bacteria

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
This study reveals estragole's bactericidal activity against MDR/XDR Gram‐negative pathogens. Synergy with meropenem and tobramycin was observed in > 88% of strains, reducing antibiotic MICs up to 16‐fold. Estragole represents a promising therapeutic adjuvant to enhance antibiotic efficacy and combat antimicrobial resistance.
María Araque, Luis B. Rojas
wiley   +1 more source

Screening of Heavy Metals Tolerance among Beta-Lactamase Producing Bacteria from Contaminated Soil and Waste Water of Some Abattoirs in Adamawa State

UMYU Journal of Microbiology Research
Bacterial adaptability enables them to tolerate various stresses, including those from antibiotics and heavy metals.  This study aims to investigate the tolerance to heavy metals, as well as the production of beta-lactamase and metallo-beta-lactamase ...
Ja’afaru, M. I., Bristone J Pola, Pukuma, M. S., Emmanuel Ijabani   +3 more
doaj   +1 more source

The effect of imipenem and diffusible signaling factors on the secretion of outer membrane vesicles and associated Ax21 proteins in Stenotrophomonas maltophilia [PDF]

, 2015
Outer membrane vesicles (OMVs) are small nanoscale structures that are secreted by bacteria and that can carry nucleic acids, proteins, and small metabolites. They can mediate intracellular communication and play a role in virulence.
Bart eDevreese, Gonzalez eVan Driessche, Jolien eVitse, Koen eRaemdonck, Laurence eVan Oudenhove, Riet eDerycke, Riet eDerycke, Simon eDevos, Stephan eStremersch, Wouter eVan Putte   +9 more
core   +2 more sources

New Delhi metallo-beta-lactamase 1-producing Enterobacteriaceae: emergence and response in Europe [PDF]

, 2010
The European NDM-1 Survey Participants: Manuela Caniça (Departamento de Doenças Infecciosas do INSA)Acquired carbapenemases confer extensive antibiotic resistance to Enterobacteriaceae and represent a public health threat. A novel acquired carbapenemase,
Giesecke, J ., Magiorakos, A. P., Monnet, D. L., O’Connor, F. Santos, Struelens, M. J., The European NDM-1 Survey Participants   +5 more
core  

Multidrug-resistant Pseudomonas aeruginosa: an endemic problem in Brazil [PDF]

, 2011
Relatos mundiais têm documentado a problemática da endemicidade de isolados clínicos de Pseudomonas aeruginosa multirresistente (MDR) aliada a elevados índices de morbidade/mortalidade. No Brasil, surtos de infecção ocasionados por P. aeruginosa têm sido
LEVY, Carlos E., LINCOPAN, Nilton, MAMIZUKA, Elsa M., NEVES, Patrícia R.   +3 more
core   +2 more sources

Approachable Synthetic Methodologies for Second-Generation β-Lactamase Inhibitors: A Review

Pharmaceuticals
Some antibiotics that are frequently employed are β-lactams. In light of the hydrolytic process of β-lactamase, found in Gram-negative bacteria, inhibitors of β-lactamase (BLIs) have been produced.
Noor Fatima, Shehla Khalid, Nasir Rasool, Muhammad Imran, Bushra Parveen, Aqsa Kanwal, Marius Irimie, Codrut Ioan Ciurea   +7 more
doaj   +1 more source

Molecular Epidemiology and Clinical Implications of Metallo-β-Lactamase-Producing Pseudomonas aeruginosa Isolated from Urine [PDF]

, 2014
We conducted a study on molecular epidemiology and clinical implications of metallo-β-lactamase (MBL)-producing Pseudomonas aeruginosa isolated from urine. Over a 10-year period from 2001 through 2010, a total of 92 MBL-producing P.
Ishii, Ayano, Kariyama, Reiko, Kokeguchi, Susumu, Kumon, Hiromi, Kusano, Nobuchika, Mitsuhata, Ritsuko, Sako, Shinichi, Uehara, Shinya, Wada, Koichiro, Yamamoto, Masumi   +9 more
core   +1 more source

Structure of apo- and monometalated forms of NDM-1--a highly potent carbapenem-hydrolyzing metallo-β-lactamase.

PLoS ONE, 2011
The New Delhi Metallo-β-lactamase (NDM-1) gene makes multiple pathogenic microorganisms resistant to all known β-lactam antibiotics. The rapid emergence of NDM-1 has been linked to mobile plasmids that move between different strains resulting in world ...
Youngchang Kim, Christine Tesar, Joseph Mire, Robert Jedrzejczak, Andrew Binkowski, Gyorgy Babnigg, James Sacchettini, Andrzej Joachimiak   +7 more
doaj   +1 more source

Genetic and biochemical characterization of a novel metallo-beta-lactamase, TMB-1, from an Achromobacter xylosoxidans strain isolated in Tripoli, Libya [PDF]

, 2012
An Achromobacter xylosoxidans strain from the Tripoli central hospital produced a unique metallo-β-lactamase, designated TMB-1, which is related to DIM-1 (62%) and GIM-1 (51%). bla was embedded in a class 1 integron and located on the chromosome. The TMB-
Borra, Pardha Saradhi, EL Salabi, Allaaeddin, Samuelsen, Orjan, Toleman, Mark A., Walsh, Timothy R.   +4 more
core   +2 more sources

New Delhi metallo-beta-lactamase 1-producing Enterobacteriaceae: emergence and response in Europe [PDF]

, 2011
To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldAcquired carbapenemases confer extensive antibiotic resistance to Enterobacteriaceae and represent a public health threat.
European NDM-1 Survey Participants, Giesecke, J, Gudlaugsson O, Kristinsson K G, Magiorakos, A P, Monnet, D L, Santos O'Connor, F, Struelens, M J   +7 more
core