Results 111 to 120 of about 905,435 (191)

Molecular Epidemiology of Pseudomonas aeruginosa Isolated from Burn Patients

Armaghane Danesh Bimonthly Journal, 2014
Background & aim: Because of emerging multi-drug resistance (MDR) Pseudomonas aeruginosa strains, treatment of burn patients infected by this bacterium is difficult.
m Anvarinejad, a Japoni, n Rafaatpour, a Alipour, p Abbasi, m Shahidi, j Mardaneh   +6 more
doaj  

Characterisation of the vibrio cholerae antibiotic resistance var operon [PDF]

, 2007
The discovery and use of antibiotics in the chemotherapy of bacterial infections has revolutionised medicine as it is today. Unfortunately, the progressive use of antibiotics has promoted the evolution of bacterial defences against these mediators and ...
Massam-Wu, Teresa
core  

"Golden Era of Antibiotics" - Coming to an end !!!

SRM Journal of Research in Dental Sciences, 2012
Resistance to antibiotics is increasing at an alarming rate. This is due to superbugs, producing heterogenous groups of enzymes, β-lactamases which inactivate β-lactam antibiotics and others as well.
V Vinodhini, T S Subashini, K S Sridevi Sangeetha, R Shivakumar, Nafeesa Iqbal   +4 more
doaj  

Synergistic combination of ceftazidime and avibactam with Aztreonam against MDR Klebsiella pneumoniae in ICU patients

Scientific Reports
The proliferation of multidrug-resistant, metallo-beta-lactamase-producing Klebsiella pneumoniae (MBL-producing K. pneumoniae) poses a major threat to public health resulting in increasing treatment costs, prolonged hospitalization, and mortality rate ...
Sally Khattab, Aya Mohamed Askar, Hidi A. A. Abdellatif, Amira A. A. Othman, Amal H. Rayan, Hasnaa Azab   +5 more
doaj   +1 more source

Mechanistic and Spectroscopic Studies of Metallo-β-lactamase NDM-1

, 2016
In an effort to biochemically characterize metallo-β-lactamase NDM-1, we cloned, overexpressed, purified, and characterized several maltose binding protein (MBP)–NDM-1 fusion proteins with different N-termini (full-length, Δ6, Δ21, and Δ36).
Michael W. Crowder (1319943), Alyssa M. Hetrick (2085961), Hao Yang (328526), Timothy K. Richmond (2085958), Mahesh Aitha (1319940), David L. Tierney (1314624)   +5 more
core   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Design of dipicolinic acid derivatives as New Delhi metallo-β-lactamase-1 inhibitors using a combined computational approach

, 2019
New Delhi metallo-β-lactamase (NDM-1) is the most recent addition to the class of metallo-β-lactamases (MBLs). This enzyme leads to antibiotic resistance in clinical treatments owing to its exertion of hydrolysis activity in almost all clinically ...
Xiaodi Niu (287991), Guizhen Wang (1800793), Yanan Yang (257193), Xiyan Wang (457117), Yawen Gao (5046800), Yiding Yu (701906), Lin Sun (105539)   +6 more
core   +1 more source

Frequency of Metallo-β-Lactamase and Antimicrobial Resistance Patterns of Acinetobacter Baumannii in Carbapenem-Resistant Isolates from Intensive Care Units of the Hospitals in Isfahan City, Iran

مجله دانشکده پزشکی اصفهان, 2015
Background: Acinetobacter baumannii is a gram-negative non-fermenting cocobacill or cocci, which is mostly found in soil, different water sources, and many healthcare environments. It is intrinsically resistance to many antibiotics.
Jina Vazirzadeh, Parisa Behshood, Leila Heidari, Hasan Ghajavand   +3 more
doaj  

Simple Method for Detection of Metallo – β–Lactamase Among Gram Negative Isolates

Online Journal of Health & Allied Sciences, 2015
Background: Carbapenem resistance due to the production of metallo-β -lactamase (MBL) in Gram-negative organism is an increasing public health problem.
Agrawal R, Sumana MN, Kishore A, Kulkarni M   +3 more
doaj  

An Evaluation of Beta-Lactamase Prevalence and the Increasing Incidence of MBL in Gram-Negative Bacteria

Online Journal of Health & Allied Sciences
Purpose: β-lactamase mediated resistance mechanisms in gram-negative bacteria play a pivotal role in spreading antimicrobial resistance. We conducted this study to understand the prevalence of β-lactamases in Gram-negative bacteria in our region ...
Amrita Joshi, Suhas Nirkhiwale, Sheetal Bhasin, Aparna Tripathi   +3 more
doaj