Results 131 to 140 of about 52,332 (219)

Antibacterial Activity of Estragole From Ocimum tenuiflorum, and Tagetes lucida and Synergistic Effect With Meropenem and Tobramycin Against Multidrug‐ and Extensively Drug‐Resistant (MDR‐XDR) Gram‐Negative Bacteria

open access: yesMicrobiologyOpen, Volume 15, Issue 1, February 2026.
This study reveals estragole's bactericidal activity against MDR/XDR Gram‐negative pathogens. Synergy with meropenem and tobramycin was observed in > 88% of strains, reducing antibiotic MICs up to 16‐fold. Estragole represents a promising therapeutic adjuvant to enhance antibiotic efficacy and combat antimicrobial resistance.
María Araque, Luis B. Rojas
wiley   +1 more source

The European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food in 2023–2024

open access: yesEFSA Journal, Volume 24, Issue 2, February 2026.
Abstract This report presents the main findings of the 2023–2024 harmonised antimicrobial resistance (AMR) monitoring in Salmonella spp., Campylobacter jejuni and Campylobacter coli from humans, food‐producing animals (broilers, laying hens, fattening turkeys, fattening pigs and bovines under 1 year of age), and derived meat.
European Food Safety Authority (EFSA)   +1 more
wiley   +1 more source

Diversity and Proliferation of Metallo-β-Lactamases: a Clarion Call for Clinically Effective Metallo-β-Lactamase Inhibitors

open access: yesApplied and Environmental Microbiology, 2018
The worldwide proliferation of life-threatening metallo-β-lactamase (MBL)-producing Gram-negative bacteria is a serious concern to public health. MBLs are compromising the therapeutic efficacies of β-lactams, particularly carbapenems, which are last ...
Anou M. Somboro   +4 more
semanticscholar   +1 more source

Complete sequence of the IncA/C 1 plasmid pCf587 carrying bla PER-2 from citrobacter freundii [PDF]

open access: yes, 2018
The bla PER-2 -harboring plasmid pCf587 (191,541 bp) belongs to lineage IncA/C 1 and is closely related to pRA1. It contains a large resistance island including the bla PER-2 gene between two copies of ISKox2-like elements, the toxin-antitoxin module ...
Dabos, Laura   +5 more
core   +1 more source

Dissemination of blaIMP-8 among Enterobacteriaceae isolates from a Buenos Aires Hospital [PDF]

open access: yes, 2013
Entre agosto de 2008 y diciembre de 2011 se detectaron en el Hospital Interzonal General de Agudos «Evita» de Lanús 6 aislamientos de enterobacterias productoras de metalo- β-lactamasas, distribuidos en tres especies: Enterobacter cloacae (4), Klebsiella
Anchordoqui, María S.   +9 more
core  

Phenotypic detection of AmpC β-lactamases, extended-spectrum- β-lactamases and metallo-β-lactamases in Enterobacteriaceae using a resazurin microtitre assay with inhibitor-based methods. [PDF]

open access: yes
Dissemination of antibiotic resistance in Enterobacteriaceae mediated by AmpC, ESBL and MBL β-lactamases is clinically significant. A simple, relatively quick method for the detection of these resistance phenotypes would greatly improve chemotherapeutic ...
Aung   +11 more
core   +1 more source

Emergence of NDM-1-producing Enterobacteriaceae in China [PDF]

open access: yes, 2012
postprin
Cheng, VCC   +4 more
core   +1 more source

A Novel β-lactam/β-lactamase Inhibitor: Ceftolozane/tazobactam

open access: yesMediterranean Journal of Infection, Microbes and Antimicrobials, 2019
Ceftolozane/tazobactam is a novel generation cephalosporin and β-lactamase inhibitor combination antibiotic. It was approved for the treatment of adults (18 years and older) with complicated intraabdominal infections used in combination with ...
Kıvanç ŞEREFHANOĞLU
doaj   +1 more source

Repurposing of Meropenem and Nadifloxacin for Treatment of Burn Patients? [PDF]

open access: yes, 2009
The escalating number of multidrug resistant pathogens has demanded the swift development of new and potent antibiotics (ref. 2). Metallo-[beta]-lactamases (MBLs) continue to evolve, rendering the latest generation of carbapenem antibiotics useless (ref.
Christie E. Costa   +5 more
core   +1 more source

Theoretical studies of the hydrolysis of antibiotics catalyzed by a metallo-B-lactamase [PDF]

open access: yes, 2015
In this paper, hybrid QM/MM molecular dynamics (MD) simulations have been performed to explore the mechanisms of hydrolysis of two antibiotics, Imipenen (IMI), an antibiotic belonging to the subgroup of carbapenems, and the Cefotaxime (CEF), a third ...
Bertrán, Juan   +3 more
core   +2 more sources

Home - About - Disclaimer - Privacy