Antarctic soil microbiomes encode structurally conserved and phylogenetically diverse beta‐lactamases [PDF]
Antimicrobial resistance is a major global health threat shaped not only by clinical settings but also by environmental reservoirs, in line with the One Health framework.
José Coche‐Miranda +8 more
doaj +3 more sources
Background: Resistance to broad‑spectrum beta‑lactams, mediated by extended‑spectrum beta‑lactamases, and metallo‑beta‑lactamase enzymes, is an increasing problem worldwide.
Sakar Bakr Smail, Kamal I. AL-OTRACHI
exaly +3 more sources
False Positive Phenotypic Detection of Metallo-Beta-Lactamases in Acinetobacter Baumannii [PDF]
Phenotypic detection of metallo-β-lactamases (MBLs) in Acinetobacter (A.) baumannii is a serious challenge to clinical microbiologists. MBLs are inhibited by metal chelators such as ethylenediaminetetraacetic acid) (EDTA).
Branka Bedenić +9 more
doaj +2 more sources
Background: Resistance to broad-spectrum beta-lactams, mediated by extended-spectrum beta-lactamases (ESBL), AmpC beta-lactamase, and metallo-beta-lactamase (MBL) enzymes, is an increasing problem worldwide. Aim of the study: This study was undertaken to
Varun Goel +2 more
exaly +3 more sources
Aim: This study aimed to identify Gram-negative uropathogens (GN-UP)-producing extended-spectrum beta-lactamases (ESBL), metallo-beta-lactamases (MBL), and AmpC enzymes in diabetic patients and to analyze their antibiotic resistance profiles.
Satish R Patil +3 more
doaj +2 more sources
Exploring New Delhi Metallo Beta Lactamases in Klebsiella pneumoniae and Escherichia coli: genotypic vs. phenotypic insights [PDF]
Background Carbapenemase-producing Enterobacterales pose a serious clinical threat, particularly in high-burden settings of carbapenem-resistant Escherichia coli and Klebsiella pneumoniae (CREK), where rapid detection tools are essential to aid patient ...
Noor Ul Ain +4 more
doaj +2 more sources
Biochemical Characterization of QPX7728, a New Ultrabroad-Spectrum Beta-Lactamase Inhibitor of Serine and Metallo-Beta-Lactamases. [PDF]
Maxim Totrov +2 more
exaly +2 more sources
Background: Resistance to beta-lactam antibiotics is widespread among Acinetobacter strains. Plasmid-mediated metallo beta lactamases (MBL) are responsible for carbapenem resistance, as are oxacillinases (OXA).
M. Duygu Aksoy +2 more
exaly +3 more sources
Spectrum of Beta-Lactamase Inhibition by the Cyclic Boronate QPX7728, an Ultrabroad-Spectrum Beta-Lactamase Inhibitor of Serine and Metallo-Beta-Lactamases: Enhancement of Activity of Multiple Antibiotics Against Isogenic Strains Expressing Single Beta-Lactamases. [PDF]
Maxim Totrov +2 more
exaly +2 more sources
Antimicrobial resistance of gram-negative pathogens isolated from hospitalized patients in Rostov region [PDF]
Objective. To evaluate resistance rates to carbapenems and III–IV generation cephalosporins among gramnegative bacteria, including production of carbapenemases and extended-spectrum beta-lactamases (ESBL). Materials and Methods.
Kutsevalova O.Yu. +4 more
doaj +1 more source

