Results 31 to 40 of about 3,638 (161)

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

open access: yesAdvanced Science, Volume 13, Issue 37, 3 July 2026.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv   +8 more
wiley   +1 more source

Protein import into chloroplasts: new aspects of a well-known topic [PDF]

open access: yes, 2007
Protein import into plant chloroplasts is a fascinating topic that is being investigated by many research groups. Since the majority of chloroplast proteins are synthesised as precursor proteins in the cytosol, they have to be posttranslationally ...
Bölter, Bettina   +2 more
core   +1 more source

Protein Homeostasis and Mitochondrial Quality Control in Neurodegeneration

open access: yesWIREs Mechanisms of Disease, Volume 18, Issue 4, July/August 2026.
Quality control pathways form an integrated proteostasis–mitochondrial quality control axis that maintains mitochondrial and cellular homeostasis. Failure of this coordinated network drives neuronal decline and contributes to neurodegeneration. ABSTRACT Quality control (QC) processes include a network of cellular pathways that prevent the accumulation ...
Rosa Di Lorenzo   +5 more
wiley   +1 more source

Safety evaluation of an extension of use of the food enzyme bacillolysin from the non‐genetically modified Bacillus amyloliquefaciens strain HPN 131

open access: yesEFSA Journal, Volume 24, Issue 7, July 2026.
Abstract The food enzyme bacillolysin (bacillus metalloendopeptidase, EC 3.4.24.28) is produced with the non‐genetically modified Bacillus amyloliquefaciens strain HPN 131 by Kerry Ingredients & Flavours Ltd. The safety of this food enzyme was evaluated previously and it did not give rise to safety concerns when used in seven food manufacturing ...
EFSA Panel on Food Enzymes (FEZ)   +15 more
wiley   +1 more source

Genome‐Wide In Silico Analysis of the Type VI Secretion System (T6SS) Within the Morganella Genus

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
▪ Species‐specific T6SS patterns among Morganella genus (M. morganii and M. sibonii). ▪ Only one‐third of M. morganii isolates haboured a T6SS. ▪ All M. sibonii possess four T6SS clusters. ▪ M. sibonii exhibited a wide diversity of effectors compared to M. morganii.
Mathilde Duque   +4 more
wiley   +1 more source

Safety evaluation of the food enzyme bacillolysin from the non‐genetically modified Bacillus amyloliquefaciens strain BP

open access: yesEFSA Journal, Volume 24, Issue 6, June 2026.
Abstract The food enzyme bacillolysin (EC 3.4.24.28) is produced with the non‐genetically modified Bacillus amyloliquefaciens strain BP by HBI Enzymes Inc. The food enzyme is intended to be used in eight food manufacturing processes. Since residual amounts of total organic solids (TOS) are removed in one process, dietary exposure was calculated for the
EFSA Panel on Food Enzymes (FEZ)   +17 more
wiley   +1 more source

The Cellular Response Capacity as Diagnostic Head Start in Neutrophil Endotoxemia Sensing

open access: yesThe FASEB Journal, Volume 40, Issue 10, 31 May 2026.
This study introduces the neutrophil cellular response capacity (CRC), a flow‐cytometry‐based approach for detecting prior endotoxin exposure across the inflammatory continuum in human whole blood. By comparing baseline and ex vivo restimulated neutrophil marker expression, the CRC identified low‐dose LPS exposure with greater analytical sensitivity ...
David Alexander Christian Messerer   +13 more
wiley   +1 more source

Serum Proteomic Analysis Using Gel‐Based Liquid Chromatography Tandem Mass Spectrometry Reveals Differences Between Canine Oral Malignancies and Non‐Malignant Conditions

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This study establishes a GeLC‐MS/MS‐based serum proteomics workflow for canine oral oncology to differentiate malignancies from non‐malignant conditions. Comprehensive protein profiling, pathway analysis and protein–drug interaction mapping reveal candidate biomarkers and insights into the pathogenesis of canine oral cancers.
Sekkarin Ploypetch   +4 more
wiley   +1 more source

Safety evaluation of the food enzyme containing metalloendopeptidase and leucyl aminopeptidase activities from the non‐genetically modified Aspergillus oryzae strain HBI‐POP01

open access: yesEFSA Journal, Volume 24, Issue 5, May 2026.
Abstract The food enzyme containing metalloendopeptidase (EC 3.4.24) and leucyl aminopeptidase (EC 3.4.11.1) activities is produced with the non‐genetically modified Aspergillus oryzae strain HBI‐POP01 by HBI Enzymes Inc. The food enzyme was considered free from viable cells of the production organism.
EFSA Panel on Food Enzymes (FEZ)   +19 more
wiley   +1 more source

Associations of Neprilysin and Its Coding Gene Variation With Hypertension in Chinese Adults

open access: yesThe Journal of Clinical Hypertension, Volume 28, Issue 4, April 2026.
ABSTRACT Neprilysin (NEP) degrades several vasoactive peptides and may contribute to blood pressure maintenance. This study aims to examine the associations between serum NEP levels and variants at its coding gene and hypertension in a general Chinese population.
Junting Hu   +14 more
wiley   +1 more source

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