Results 111 to 120 of about 23,484 (216)

Anti‐Photoaging Effects and Potential Molecular Mechanisms of Ergothioneine‐Derived‐Ganoderma lucidum on UVB‐Irradiated Skin

Food Frontiers, Volume 7, Issue 2, March 2026.
Anti‐photoaging effects of Ganoderma lucidum‐derived ergothioneine in UVB‐irradiated HaCaT cells and skin photoaging mice. ABSTRACT The increasing incidence of skin photoaging associated with enhanced ultraviolet (UV) exposure highlights the need for effective preventive and therapeutic interventions.
Zihao Zong, Zhenhao Li, Ming Yin, Yuanhang Yao, Ben Niu, Huizhi Chen, Ruiling Liu, Jing Xu, Chaoyi Shen, Hangjun Chen, Lijun You, Weijie Wu, Haiyan Gao   +12 more
wiley   +1 more source

Cluster of Severe Arginase 1 Deficiency in the Comoros: Clinical, Neuroimaging, and Molecular Features in 17 Patients From Mayotte Compared With 10 From Paris

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Arginase 1 deficiency (ARG1D) is the least common urea cycle disorder. Neonatal onset is rarely described, and hyperammonemic coma is less common in patients with ARG1D compared to other urea cycle disorders. In recent years, we diagnosed a high number of ARG1D patients in Mayotte, an insular (Comoro Islands) department of France.
Aurélie De Bruyne, Apolline Imbard, Charles‐Joris Roux, Abdourhahim Chamouine, Camille Schwab, Anaïs Brassier, Jean‐Baptiste Arnoux, Juliette Bouchereau, Cécile Laroche‐Raynaud, Tristan Mekdade, Margaux Gaschignard, Claire‐Marine Berat, Clément Pontoizeau, Stéphanie Gobin‐Limballe, Pascale de Lonlay, Jean‐François Benoist, Manuel Schiff   +16 more
wiley   +1 more source

A la carte bioprospecting of substrate‐selective laccases via high‐throughput computational enzyme–substrate interaction profiling

Protein Science, Volume 35, Issue 3, March 2026.
Abstract Laccases are versatile, multicopper oxidases with broad biotechnological applications due to their ability to oxidize a wide range of substrates. Here, we introduce a computational pipeline that combines sequence filtering, Monte Carlo simulations, and quantum mechanical spin density calculations to identify laccase candidates tailored to ...
Ruite Xiang, Helena Balfagon Campos, Arnau Bassegoda, Lars H. Østergaard, Kirk M. Schnorr, Victor Guallar   +5 more
wiley   +1 more source

The Impact of Feeding Organic Trace Minerals Using Advanced Chelate Technology on Reproductive Efficiency and Blood Parameters in Ghezel Ewes

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
Supplementing the flushing diet with organic trace minerals based on advanced chelate technology enhanced the reproductive performance of ewes as compared with inorganic trace minerals. ABSTRACT Background The bioavailability of trace minerals (TM) in a diet is important for improving reproductive performance and fertility parameters.
Sedigheh Vatankhah, Marziyeh Ebrahimi, Gholamali Moghaddam, Davoud Kianifard, Akbar Taghizadeh, Reza Asadpour, Mohammad Hassan Nazaran   +6 more
wiley   +1 more source

Rational Design of Artificial Metalloproteins and Metalloenzymes with Metal Clusters

Molecules, 2019
Metalloproteins and metalloenzymes play important roles in biological systems by using the limited metal ions, complexes, and clusters that are associated with the protein matrix.
Ying-Wu Lin
doaj   +1 more source

Coupled on‐line in crystallo UV–Vis absorption spectroscopy and X‐ray crystallography to compare specific radiation damage in metal‐containing proteins at room versus cryogenic temperature

Acta Crystallographica Section D, Volume 82, Issue 3, Page 187-198, March 2026.
We used on‐line in crystallo UV–Vis absorption spectroscopy in conjunction with X‐ray crystallography on beamline BM07‐FIP2 at the ESRF to compare the structural effects of specific radiation damage on two different metal‐containing proteins at either room or cryogenic temperature.Specific radiation damage (SRD) to proteins is a pertinent issue ...
Nicolas Caramello, Samuel L. Rose, Eric Mathieu, Lucas Petit, Ivo Tews, Sylvain Engilberge, Antoine Royant   +6 more
wiley   +1 more source

The effects of zinc sulfate on ethyl glucuronide immunoassay urine testing [PDF]

, 2016
Published research in the Journal of Analytical Toxicology and the American Society for Clinical Pathology has confirmed that the presence of Zinc Sulfate in adulterated urine samples can influence the testing results using EMIT and ELISA immunoassay ...
Cawley, Shanna Marie
core   +1 more source

Hydrazine Synthase From Anammox Is Inhibited by Linear and Aromatic Alkynes

Environmental Microbiology, Volume 28, Issue 3, March 2026.
Linear and aromatic alkynes inhibit anammox in culture and in wetlands. The inhibition by alkynes is specific to the hydrazine synthase, a key enzyme in the anammox pathway. ABSTRACT N2O emissions by nitrifiers are often estimated using selective inhibitors, such as 1‐alkynes.
Cerys Maryan, Guylaine H. L. Nuijten, Andrew T. Crombie, Sebastian Lücker, Victoria Gibson, Marcela Hernández, J. Colin Murrell, Laura E. Lehtovirta‐Morley   +7 more
wiley   +1 more source

Gram‐Scale Synthesis of an Arylsulfonamide‐Type Alkaline Phosphatase Inhibitor

ChemMedChem, Volume 21, Issue 4, 25 February 2026.
A larger amount of a tissue‐nonspecific alkaline phosphatase inhibitor, 5‐((5‐chloro‐2‐methoxyphenyl)sulfonamido)nicotinamide, was synthesized in five steps using a parallel method without the need for chromatography or crystallization. Because a single batch was used for in vivo studies in a large population of mice, the pharmacological results were ...
Zsolt Rapi, Krisztina Fülöp, Zoltán Mucsi   +2 more
wiley   +1 more source

4‐(5‐Chloro‐3‐(3,4,5‐trimethoxybenzoyl)‐1H‐indol‐1‐yl)benzenesulfonamide: A Novel Polypharmacology Agent to Target Carbonic Anhydrase IX and XII With Improved Selectivity, Wnt/β‐Catenin Signaling Pathway, and P‐Glycoprotein

ChemMedChem, Volume 21, Issue 4, 25 February 2026.
Polypharmacology is expected to produce higher therapeutic efficacy and lower cytotoxic and side effects. Compound 15 exhibited strong inhibition of the human carbonic anhydrase isoforms IX and XII and selectivity toward the adverse isoforms I and II.
Michela Puxeddu, Rosa Bordone, Claudia Colla, Gabriele Rotili, Antonio Coluccia, Pietro Sciò, Petra Cuřínová, Alessio Nocentini, Claudiu T. Supuran, Serena Filiberti, Marta Turati, Roberto Ronca, Joanna Kopecka, Chiara Riganti, Lucia Jimenez, Wolfgang Link, Chiara Bigogno, Giulio Dondio, Martina Barba, Gianluca Canettieri, Romano Silvestri, Giuseppe La Regina   +21 more
wiley   +1 more source