Results 81 to 90 of about 11,336 (207)

Isocyanides as a Chemical Tool for Identifying [Fe]‐Hydrogenase‐Dependent Methanogenesis

ChemBioChem, Volume 27, Issue 17, 14 September 2026.
In model methanogens, [Fe]‐hydrogenase (Hmd) substitutes nickel‐dependent hydrogenases under nickel‐limited conditions. We determined the inhibitory effects of the Hmd inhibitor, isocyanides, on methanogenesis in a cell extract and in a cell suspension.
Shunsuke Nomura, Seigo Shima
wiley   +1 more source

Bioinspired Zinc Macrocycles Confined in UiO‐67: A Heterogeneous Synzyme for Sustainable CO2 Valorization

ChemSusChem, Volume 19, Issue 17, 14 September 2026.
By mimicking nature’s use of weak supramolecular interactions, zinc macrocycles are assembled within defective UiO‐67 to create cooperative synzymes for CO2 valorization. Confined amines, hydrogen‐bonding networks and accessible iodides work in concert to activate CO2 and epoxides at ambient pressure, delivering additive‐free catalysis that outperforms
J. E. Chiva, J. E. Sánchez‐Velandia, F. Esteve, F. G. Cirujano, C. Vicent, N. Martín, B. Altava, E. García‐Verdugo   +7 more
wiley   +1 more source

The Role of Iron‐Hyponitrite Intermediates in Biology and Insights From Synthetic Model Complexes

Chemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.
Despite the difference in active site architecture, NO reduction by different NOR enzymes is expected to be linked by a common intermediate: hyponitrite (N2O22−). However, experimentally, very little is known about the coordination chemistry of iron with hyponitrite and the expected Fe‐hyponitrite intermediates.
Michael O. Lengel, Nicolai Lehnert
wiley   +1 more source

Covalent Insertion of a Mn(Salen) Type Complex in Cross‐Linked Protein Crystals: Design of an Enantioselective Artificial Epoxidase

Chemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.
An Artificial metalloenzyme was designed by a Michael addition between a MnSalen complex and a cysteine residue within NikA crystals. The heterogeneous catalyst was found capable of an enantioselective and stereospecific epoxidation of cis‐β‐methylstyrene in cristallo.
Manel Boukhallat, Ismail Benhamed, Jade Arnone, Stann Van Baaren, Clara Rinaldi, Patrice Catty, Caroline Marchi‐Delapierre, Christine Cavazza, Stéphane Ménage   +8 more
wiley   +1 more source

How Proton Incorporation Reshapes Lattice Dynamics In BaSnO3‐Type Proton Conductors

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Yttrium‐doped BaSnO3 exhibits isotope‐dependent changes in its low‐energy vibrational density of states upon hydration. Comparison of dry, H2O‐, and D2O‐treated samples re‐veals mass‐dependent phonon renormalization linked to proton dynamics near oxygen va‐cancies, providing experimental insight into hydrogen‐coupled lattice excitations in proton ...
Artur Braun, Alexey Rulev, Nobumoto Nagasawa, Hongxin Wang, Tatyana Bendikov, Vladimir Pomjakushin, Martin Kunz, Yoshitaka Yoda, Qianli Chen, Stephen P. Cramer   +9 more
wiley   +1 more source

From Identification to Enzymatic Activity Profiling: Comprehensive Characterization of BloCAβ, a Probiotic β‐Carbonic Anhydrase From Bifidobacterium longum

Archiv der Pharmazie, Volume 359, Issue 9, September 2026.
Production and biochemical characterization of a new β‐carbonic anhydrase from the probiotic Bifidobacterium longum, one of the main players of human gut microbiota. ABSTRACT The microbiota comprises communities of microorganisms that establish complex relationships with the host and play key roles in physiology, metabolism, and immunity.
Simone Giovannuzzi, Andrea Ammara, Simone Carradori, Viviana De Luca, Marialucia Gallorini, Damiano Iacovozzi, Amelia Cataldi, Ilaria D'Agostino, Davide Moi, Valentina Onnis, Claudiu T. Supuran, Clemente Capasso   +11 more
wiley   +1 more source

Acquired Zinc Deficiency in Preterm Infant Post-Surgery for Necrotizing Enterocolitis (NEC) on Prolonged Total Parenteral Nutrition (TPN)

Pediatric Reports
Zinc (Zn) is a vital trace element that plays a pivotal role in protein synthesis, cellular growth, and differentiation and is involved as a cofactor of metalloenzymes, performing a wide variety of metabolic, immune, and synthesis roles.
Mansour Al Qurashi, Hadeel Mohammad, Syed Sameer Aga, Ahmed Mustafa, Jubara Alallah, Mohammed Al Hindi, Mohammed Al Harbi, Mohammed Hasosah   +7 more
doaj   +1 more source

Sulfonamide‐Based 2‐Amino‐1,3,4‐Oxadiazole Derivatives as Dual Cholinesterase and Carbonic Anhydrase Inhibitors: Design, Synthesis, Kinetic Characterization, Molecular Modeling, and ADMET Evaluation

Drug Development Research, Volume 87, Issue 6, September 2026.
ABSTRACT In this study, 12 novel sulfonamide derivatives incorporating 2‐amino‐1,3,4‐oxadiazole and 1,3‐benzazol‐2(3H)‐one scaffolds were synthesized and structurally characterized using 1H NMR, 13C NMR, and LC–MS analyses. Their inhibitory activities were evaluated against acetylcholinesterase (AChE), butyrylcholinesterase (BChE), carbonic anhydrase I
Gülnur Arslan Karahan, Başak Gökçe, Muhammed Tilahun Muhammed, Emre Kadir Ayan, Azime Berna Özçelik   +4 more
wiley   +1 more source

Effects of Blanching on Phytochemical Retention, Antioxidant Capacity, and Microstructure of Banana Flower (Musa spp., Musaceae)

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Hot‐water blanching (100°C, 1–5 min), citric acid treatment (1%–5% w/v in water), and microwave blanching (720 W, 30–40 s) were employed to modify the bioactive compounds of banana flowers. Microwave blanching for 40 s yielded the highest amounts of total phenolics (7.60 mg GAE/g), total flavonoids (4.90 mg QE/g), and antioxidant activity.
Saurabh Bhosle, Sonia Morya, Robert Mugabi   +2 more
wiley   +1 more source

Quinoline and Phthalimide Substituted Silicon Phthalocyanines as Multi‐Target Inhibitors of Cholinesterases and Carbonic Anhydrases

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Two novel axially substituted silicon phthalocyanines were synthesized and characterized. Compound 2a exhibited significantly enhanced inhibition of AChE, BChE, hCA I and hCA II, supported by molecular docking and SAR analysis, highlighting its potential as a multifunctional enzyme inhibitor with promising biological activity.
Seda Ünlü, Zeynep Köksal, Kevser Kübra Kırboğa, Fikriye Tuncel Elmalı   +3 more
wiley   +1 more source