Results 71 to 80 of about 11,336 (207)

Activation studies of the α- and β-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae with amines and amino acids

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
The α- and β-class carbonic anhydrases (CAs, EC 4.2.1.1) from the pathogenic bacterium Vibrio cholerae, VchCAα, and VchCAβ, were investigated for their activation with natural and non-natural amino acids and amines.
Andrea Angeli, Sonia Del Prete, Sameh M. Osman, Fatmah A. S. Alasmary, Zeid AlOthman, William A. Donald, Clemente Capasso, Claudiu T. Supuran   +7 more
doaj   +1 more source

Recent advances in Joule‐heating synthesis of functional nanomaterials for photo and electrocatalysis

PhotoMat, EarlyView.
This paper presents a comprehensive overview of recent advancements in Joule‐heating synthesis of photo and electrocatalysts, emphasizing its benefits and applications. The objective is to offer an effective strategy for enhancing the diversity and performance of catalytic materials.
Jiaqi Li, Laiyu Luo, Siyu Wang, Haojie Song, Baojiang Jiang   +4 more
wiley   +1 more source

Histone deacetylase inhibitors as venetoclax‐sensitising partners in acute myeloid leukaemia: Mechanisms, pharmacology and translational perspectives

British Journal of Pharmacology, EarlyView.
Abstract Venetoclax combined with hypomethylating agents has improved treatment for older or unfit patients with acute myeloid leukaemia (AML), but resistance and relapse remain common. This review analyses the rationale for combining venetoclax with inhibitors of histone deacetylase (HDAC).
Jaebok Lee, Marc Diederich
wiley   +1 more source

S‐Adenosylmethionine (SAM) hydrolases counter increased SAM epimerisation in thermophilic archaea

The FEBS Journal, EarlyView.
S‐Adenosyl‐l‐methionine (SAM) is a vital enzyme cofactor. Epimerisation at the sulfonium centre of biologically active (SS,SCα)‐SAM is driven by heat, yielding biologically inactive (RS,SCα)‐SAM. Here, two novel archaeal SAM hydrolases from the thermophilic Sulfolobus acidocaldarius and the halophilic Haloferax volcanii are shown to cleave (RS,SCα)‐SAM.
Agnes Bartels, Michael K. F. Mohr, Phillip Nußbaum, Marie Joest, Bianca Wassmer, Laurent Rasquin, Sonja‐Verena Albers, Jennifer N. Andexer   +7 more
wiley   +1 more source

Structural insights into θ‐type carbonic anhydrases 3 and 4: Tuning the directionality of CO2 hydration in a diatom

The FEBS Journal, EarlyView.
θ‐CA3 from a marine diatom has an N‐terminal transmembrane helix and two homologous catalytic domains. The enzyme functions as a dimer, with active sites formed near the dimer interface. A bicarbonate ion binds on the symmetry axis of the dimer and forms hydrogen bonds with both monomers, thereby activating θ‐CA3 and tuning CO2 hydration activity ...
Hiroto Negoro, Atsuki Ohsawa, Ginga Shimakawa, Hideaki Tanaka, Yusuke Matsuda, Genji Kurisu   +5 more
wiley   +1 more source

Insights into tandem dioxygenases—copper radical oxidases in fungal Phytopathogens of the Colletotrichum acutatum species complex

The FEBS Journal, EarlyView.
In Colletotrichum acutatum species complex, conserved ring‐cleavage dioxygenases located adjacent to AA5_2 enzymes were investigated as potential redox partners. Biochemical analyses identified the dioxygenases as intradiol‐cleaving enzymes preferentially oxidizing methyl‐substituted catechols, while AA5_2 enzymes displayed weak alcohol oxidase ...
Radka Končitíková, David Ribeaucourt, Mireille Haon, David Navarro, Elodie Drula, Bastien Bissaro, Jean‐Guy Berrin, Mickael Lafond   +7 more
wiley   +1 more source

Regulation of Matrix Metalloproteinases by Wine-Derived Compounds: Implications for Cancer Therapy

Biomolecules
Cancer remains a prevalent global health concern, with key factors such as diet, environment, and genetics playing significant roles in its progression.
Md. Towhedul Islam, Ha Vy Thi Vo, Hyuck Jin Lee   +2 more
doaj   +1 more source

Unveiling contrasting iron efficiency strategies in common bean (Phaseolus vulgaris L.) genotypes under iron deficiency

Plant Biology, EarlyView.
Common bean genotypes differ in their iron acquisition through distinct Strategy I responses and root exudation patterns. Abstract Iron (Fe) deficiency in food crops, particularly on calcareous soils, limits productivity and human nutrition. This study investigated two common bean (Phaseolus vulgaris) genotypes, Guaymí (high Fe‐accumulating, HI) and ...
F. X. Rucamumihigo, U. Ludewig, A. Hernández‐Pridybailo, I. Cakmak, N. J. Maywald   +4 more
wiley   +1 more source

ENZYMATIC HYDROGEN BIOPRODUCTION. STRUCTURE, FUNCTION AND APPLICATION OF HYDROGENASES [PDF]

Postępy Mikrobiologii, 2021
Małgorzata Witkowska, Agnieszka Żylicz-Stachula, Anna Struck   +2 more
doaj   +1 more source

Genomic and Phenotypic Classification of Staphylococcus Species Isolated From Delhi Air

Environmental Microbiology Reports, Volume 18, Issue 5, October 2026.
Multiple Staphylococcus spp. were isolated from the outdoor polluted air of the Indian Capital, New Delhi. The bacterial samples were collected from 6 different locations, and the whole genome of four Staphylococcus isolates was sequenced in their entirety. This study presents the comparative genomic analysis of these four isolates.
Himanshu Sen, Joyasree Das, Suman Paul, Manpreet Kaur, Amareshwar Vodapalli, Surajit Bhattacharjee, Manoj Raje, Srinivasan Krishnamurthi, Saumya Raychaudhuri   +8 more
wiley   +1 more source