Surface Immobilized His-tagged Azurin as a Model Interface for the Investigation of Vectorial Electron Transfer in Biological Systems [PDF]
A model system for the electrochemical investigation of vectorial electron transfer in biological systems was designed, assembled and characterized. Gold electrodes, functionalized with a -OCH3 terminated, aromatic self-assembled monolayer, were used as ...
Berto, Marcello +9 more
core +1 more source
From Pharmaceutical to Biophysical Therapies: New Horizons in Inflammatory Bowel Disease Management
Important limitations exist in the current pharmacological landscape of Inflammatory Bowel Disease (IBD), such as variable response rates and treatment‐limiting adverse effects. In this review, we perform a critical assessment of the current literature on novel multimodal biophysical approaches showing alternative mechanisms of action to, and potential
Benedetta Ricchi +7 more
wiley +1 more source
Oxidative stress is tightly regulated by cytochrome c phosphorylation and respirasome factors in mitochondria [PDF]
Respiratory cytochrome c has been found to be phosphorylated at tyrosine 97 in the postischemic brain upon neuroprotective insulin treatment, but how such posttranslational modification affects mitochondrial metabolism is unclear.
Díaz Moreno, Irene +7 more
core +1 more source
Hybrid NSAID–aminoacid molecules have demonstrated excellent activity in inhibiting the cyclooxygenase/lipoxygenase system. Accordingly, the present study describes the synthesis of molecules of this kind, examining their behavior via docking, molecular dynamics simulations and per‐residue energy decomposition analyses.
J. Carlos Jiménez‐Cruz +7 more
wiley +1 more source
Uji Efektivitas Beberapa Jenis Arang Aktif dan Tanaman Akumulator Logam pada Lahan Bekas Penambangan Emas [PDF]
Tujuan penelitian ini adalah untuk mengetahui efektivitas jenis arang aktif yang berasal dari bahan baku tempurung kelapa, tempurung kelapa sawit dan sekam padi serta tanaman akumulator sawi hijau, sawi huma dan sawi pahit dalam menyerap logam berat Cu ...
Mustamir, E. (Elly) +2 more
core
Cytochrome c: Surfing Off of the Mitochondrial Membrane on the Tops of Complexes III and IV [PDF]
The proper arrangement of protein components within the respiratory electron transport chain is nowadays a matter of intense debate, since altering it leads to cell aging and other related pathologies.
Díaz Moreno, Irene +4 more
core +1 more source
We used on‐line in crystallo UV–Vis absorption spectroscopy in conjunction with X‐ray crystallography on beamline BM07‐FIP2 at the ESRF to compare the structural effects of specific radiation damage on two different metal‐containing proteins at either room or cryogenic temperature.Specific radiation damage (SRD) to proteins is a pertinent issue ...
Nicolas Caramello +6 more
wiley +1 more source
Anaemic Streams: Iron and Essential Trace Metals Frequently Limit Primary Producer Biomass
Nutrient enrichment experiments in 41 streams across the eastern United States demonstrate that trace metals can limit the growth of primary producers. Trace metals are frequently co‐limiting with macronutrients and the availability of N and P in streams and watersheds are predictive of Fe and Zn limitation status.
David M. Costello +10 more
wiley +1 more source
Online immunocapture ICP-MS for the determination of the metalloprotein ceruloplasmin in human serum
Objective The human copper-protein ceruloplasmin (Cp) is the major copper-containing protein in the human body. The accurate determination of Cp is mandatory for the reliable diagnosis of several diseases.
Bogdan Bernevic +3 more
doaj +1 more source

