Results 101 to 110 of about 16,905 (266)
Abstract Peri‐implant diseases are dysbiosis‐mediated inflammatory disorders that occur in susceptible hosts. Antimicrobials and immunomodulatory agents therefore might be pertinent as adjunctive measures in the treatment of such disorders. The aim of this narrative review was to examine the existing evidence and assess the effectiveness of emerging ...
Alberto Monje+3 more
wiley +1 more source
Immunization of mice with the self-peptide ACBP coupled to keyhole limpet hemocyanin
Summary: Keyhole limpet hemocyanin (KLH) is a glycosylated multi-subunit metalloprotein that elicits a strong nonspecific immune activation, thus inducing both cellular and humoral immune responses.
Léa Montégut+5 more
doaj
Online immunocapture ICP-MS for the determination of the metalloprotein ceruloplasmin in human serum
Objective The human copper-protein ceruloplasmin (Cp) is the major copper-containing protein in the human body. The accurate determination of Cp is mandatory for the reliable diagnosis of several diseases.
Bogdan Bernevic+3 more
doaj +1 more source
Abstract The mood stabilizers lithium and valproate are psychotropic medications widely used in clinical practice. Despite their proven benefits, many individuals stop their treatment due to the adverse effects. Chronic diarrhoea is a common reason for discontinuation of these drugs; however, the underlying mechanisms are unknown.
Sofia Cussotto+10 more
wiley +1 more source
Metalloproteomics: Principles, challenges and applications to neurodegeneration
Trace elements are required for a variety of normal biological functions. As our understanding of neurodegenerative disease advances we are identifying a number of metalloenzymes involved in disease process.
Blaine Russell Roberts+6 more
doaj +1 more source
Copper(II) complexes synthesized with coumarin‐derived ligands are tested against various strains, including C. albicans and C. tropicalis. Upon penetration into the fungal cell, these complexes induce oxidative distress and generate free radicals, leading to protein and DNA damage causing cell apoptosis.
David Ezenarro‐Salcedo+8 more
wiley +1 more source
ABSTRACT Human mesenchymal stem cells (hMSCs) have been under investigation in preclinical and clinical settings for treating neurological disorders in recent years. Predominantly due to paracrine effects in vivo, hMSC‐secreted extracellular vesicles (EVs) are at the forefront of these investigations.
Shannon Helsper+7 more
wiley +1 more source
Probing metalloproteins by voltammetry [PDF]
Dynamic electrochemical methods, which have long held an important place among the techniques of the coordination chemist, have generally remained unexploited by those seeking to understand the complex and often elusive chemistry of metal centres in proteins.
openaire +2 more sources
Extracting Trends From NMR Data With TrAGICo: A Python Toolbox
TrAGICo is a Python collection of functions for the extraction and analysis of serial NMR spectroscopy data. In this tutorial, we show several practical examples, highlighting its utility for various chemical NMR applications, such as extraction of the chemical shift temperature dependence in paramagnetic systems, relaxation studies, and reaction ...
Letizia Fiorucci+10 more
wiley +1 more source