Results 11 to 20 of about 21,893 (312)

Towards the spatial resolution of metalloprotein charge states by detailed modeling of XFEL crystallographic diffraction [PDF]

open access: yesActa Crystallographica Section D: Structural Biology, 2020
Electronic configurations at distinct metal centers within a metalloprotein may be characterized by inspecting the scattering factors at the X-ray absorption edge. Such experiments may be feasible at XFEL sources, using Bayesian data analysis.
N. Sauter, J. Kern, J. Yano, J. Holton
semanticscholar   +4 more sources

Bioinformatics of Metalloproteins and Metalloproteomes [PDF]

open access: yesMolecules, 2020
Trace metals are inorganic elements that are required for all organisms in very low quantities. They serve as cofactors and activators of metalloproteins involved in a variety of key cellular processes.
Yan Zhang, Junge Zheng
doaj   +3 more sources

Metalloprotein Crystallography: More than a Structure [PDF]

open access: yesAccounts of Chemical Research, 2016
Conspectus Metal ions and metallocofactors play important roles in a broad range of biochemical reactions. Accordingly, it has been estimated that as much as 25–50% of the proteome uses transition metal ions to carry out a variety of essential functions.
Sarah E. J. Bowman   +2 more
semanticscholar   +3 more sources

An artificial CO-releasing metalloprotein built by histidine-selective metallation. [PDF]

open access: yesChemical Communications, 2015
We report the design and synthesis of an aquacarbonyl Ru(II) dication cis-[Ru(CO)2(H2O)4](2+) reagent for histidine (His)-selective metallation of interleukin (IL)-8 at site 33.
Inês S Albuquerque   +6 more
semanticscholar   +5 more sources

Machine Learning Approaches for Metalloproteins [PDF]

open access: yesMolecules, 2022
Metalloproteins are a family of proteins characterized by metal ion binding, whereby the presence of these ions confers key catalytic and ligand-binding properties.
Yue Yu, Ruobing Wang, Ruijie D. Teo
doaj   +3 more sources

Metalloproteins and neuronal death [PDF]

open access: bronzeMetallomics, 2009
Neurodegenerative diseases include Alzheimer's and Parkinson's disease that are very common and other diseases that are notorious but occur less often such as Creutzfeldt-Jakob disease. In each case a protein is closely linked to the pathology of these diseases. These proteins include alpha-synuclein, the prion protein and Aβ.
David R. Brown
openalex   +4 more sources

A high-resolution view of the coordination environment in a paramagnetic metalloprotein from its magnetic properties.

open access: yesAngewandte Chemie, 2021
Metalloproteins constitute a significant fraction of the proteome of all organisms and their characterization is critical for both basic sciences and biomedical applications.
E. Ravera   +6 more
semanticscholar   +1 more source

Toxic Metal Species and ‘Endogenous’ Metalloproteins at the Blood–Organ Interface: Analytical and Bioinorganic Aspects

open access: yesMolecules, 2021
Globally, human exposure to environmental pollutants causes an estimated 9 million deaths per year and it could also be implicated in the etiology of diseases that do not appear to have a genetic origin.
Tristen G. Bridle   +2 more
doaj   +1 more source

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