Results 31 to 40 of about 7,747 (222)
Redox Biology, 2022 Iron is an essential metal for cellular metabolism and signaling, but it has adverse effects in excess. The physiological consequences of iron deficiency are well established, yet the relationship between iron supplementation and pericellular oxygen ...
Gulsah Sevimli +12 more
doaj +1 more source
Metalloprotein-Catalyzed Click Reaction for In Situ Generation of a Potent Inhibitor
, 2020 In situ click chemistry has great potential for identifying enzyme inhibitors. However, conventional in situ click chemistry provides extremely low yields of the products, making it incompatible with direct activity-based assays.
Yutaro Hanatani (8752332) +9 more
core +1 more source
Metalloprotein Crystallography: More than a Structure [PDF]
, 2015 Metal ions and metallocofactors play important roles in a broad range of biochemical reactions. Accordingly, it has been estimated that as much as 25–50% of the proteome uses transition metal ions to carry out a variety of essential functions.
Bowman, Sarah E. J. +2 more
core +1 more source
Oxygen-Sensitive Metalloprotein Structure Determination by Cryo-Electron Microscopy
Biomolecules, 2022 Metalloproteins are involved in key cell processes such as photosynthesis, respiration, and oxygen transport. However, the presence of transition metals (notably iron as a component of [Fe-S] clusters) often makes these proteins sensitive to oxygen ...
Mickaël V. Cherrier +8 more
doaj +1 more source
The Fe Protein: An Unsung Hero of Nitrogenase
Inorganics, 2018 Although the nitrogen-fixing enzyme nitrogenase critically requires both a reductase component (Fe protein) and a catalytic component, considerably more work has focused on the latter species.
Andrew J. Jasniewski +3 more
doaj +1 more source
Enzyme‐Like Synthetic Cleft for Light‐Driven Water‐Oxidation Catalysis Via an Oxide Relay Pathway
Angewandte Chemie, EarlyView.A carboxylic acid group introduced into the second coordination sphere of a Ru(bda) water oxidation catalyst forms a defined hydrogen bond within the catalytic cleft. This interaction locks the group in place and enables an intramolecular oxide relay pathway between Ru(V)═O and the carboxylate group, providing a distinct and efficient route for O─O ...
Daniel A. P. Friedewald +7 more
wiley +2 more sources
Angewandte Chemie, EarlyView.Oxygen‐tolerant photo‐induced miniaturized accelerated atom transfer radical polymerization (OPTIMA‐ATRP) in water was developed for the polymerization of hydrophilic (meth)acrylate monomers under ambient or sub‐ambient (4°C) temperature and atmospheric conditions, without prior degassing, in less than 10 min, at an ultra‐small scale (< 50 µL) in ...
Arman Moini Jazani +5 more
wiley +2 more sources
Electrochemical gating enhances nearfield trapping of single metalloprotein junctions [PDF]
, 2023 Metalloprotein based junctions are widely used as model systems in the field of molecular bioelectronics to miniaturise electronic circuitry with help of biomolecular device components.
Aragonès, Albert C., Domke, Katrin F.
core +1 more source
Finding High-Quality Metal Ion-Centric Regions Across the Worldwide Protein Data Bank
Molecules, 2019 As the number of macromolecular structures in the worldwide Protein Data Bank (wwPDB) continues to grow rapidly, more attention is being paid to the quality of its data, especially for use in aggregated structural and dynamics analyses. In this study, we
Sen Yao, Hunter N.B. Moseley
doaj +1 more source
Frontiers in Microbiology, 2016 The regulator of citrate metabolism, CitO, from Enterococcus faecalis belongs to the FCD family within the GntR superfamily. In the presence of citrate, CitO binds to cis-acting sequences located upstream of the cit promoters inducing the expression of ...
Victor S. Blancato +5 more
doaj +1 more source