Results 61 to 70 of about 22,661 (298)

Probing the Active Site of Class 3 L-Asparaginase by Mutagenesis: Mutations of the Ser-Lys Tandems of ReAV

Biomolecules
The ReAV enzyme from Rhizobium etli, a representative of Class 3 L-asparaginases, is sequentially and structurally different from other known L-asparaginases. This distinctiveness makes ReAV a candidate for novel antileukemic therapies.
Kinga Pokrywka, Marta Grzechowiak, Joanna Sliwiak, Paulina Worsztynowicz, Joanna I. Loch, Milosz Ruszkowski, Miroslaw Gilski, Mariusz Jaskolski   +7 more
doaj   +1 more source

Immunization of mice with the self-peptide ACBP coupled to keyhole limpet hemocyanin

STAR Protocols, 2022
Summary: Keyhole limpet hemocyanin (KLH) is a glycosylated multi-subunit metalloprotein that elicits a strong nonspecific immune activation, thus inducing both cellular and humoral immune responses.
Léa Montégut, Hui Chen, José Manuel Bravo-San Pedro, Omar Motiño, Isabelle Martins, Guido Kroemer   +5 more
doaj   +1 more source

Extracellular regulation of metalloproteinases [PDF]

, 2015
Matrix metalloproteinases (MMPs) and adamalysin-like metalloproteinase with thrombospondin motifs (ADAMTSs) belong to the metzincin superfamily of metalloproteinases and they play key roles in extracellular matrix catabolism, activation and inactivation ...
Bannikov, Barcelona, Barmina, Barrett, Brew, Butler, Crabbe, Crabbe, Dumin, Elkins, Ellerbroek, Emonard, Emonard, Emonard, Etique, Fanjul-Fernández, Fosang, Fu, Fushimi, Galvez, Gendron, George, Geurts, Gillian Murphy, Gorovoy, Grimsley, Gu, Guo, Gálvez, Hahn-Dantona, Herz, Herz, Higashi, Iida, Kashiwagi, Kazuhiro Yamamoto, Kolkenbrock, Kowal, Kuno, Lafleur, Lillis, Linda Troeberg, Liu, Lu, Mantuano, Messaritou, Morgunova, Mu, Nagase, Nagase, Noguchi, Omura, Page-McCaw, Piccard, Quinn, Ra, Remacle, Rozanov, Sakamoto, Scilabra, Selvais, Shiomi, Sohail, Stricker, Strickland, Sudbeck, Takino, Thevenard, Troeberg, Troeberg, Uekita, Van den Steen, Van Wart, Visse, von Arnim, Walling, Wang, Weiss, Willingham, Winberg, Yamamoto, Yamamoto, Yamamoto, Yamamoto, Yang, Yu, Yáñez-Mó   +86 more
core   +1 more source

NMR Studies of Metalloproteins [PDF]

, 2011
Metalloproteins represent a large share of the proteomes, with the intrinsic metal ions providing catalytic, regulatory, and structural roles critical to protein functions. Structural characterization of metalloproteins and identification of metal coordination features including numbers and types of ligands and metal-ligand geometry, and mapping the ...
Sun, H, Li, H
openaire   +4 more sources

Recent Advances in Bioconjugation of Aromatic Amino Acid Residues by a Reactivity‐Guided Approach

The Chemical Record, EarlyView.
This review highlights recent advances in the bioconjugation of aromatic amino acids residues, focusing on strategies that leverage their inherent chemical reactivity to enable precise and versatile modifications of biomacromolecules, illustrating relevant applications.
Bruno M. da S. Santos, Lívia C. R. M. da Frota, Thais G. Silva, Fernanda G. Finelli   +3 more
wiley   +1 more source

Metal Complexes of Macrocyclic Ligands

CHIMIA, 1999
Metal complexes of macrocyclic ligands are studied with a view to understanding aspects of metalloprotein structure and function.
Thomas A. Kaden
doaj   +1 more source

Quantum Embedding of Non-Local Quantum Many-Body Interactions in an Prototypal Anti-Tumor Vaccine Metalloprotein on Near-Term Quantum Computing Hardware. [PDF]

Int J Mol Sci
Chachkarova E, Tse T, Yordanov Y, Wei Y, Weber C.   +4 more
europepmc   +3 more sources

Imaging of compartmentalised intracellular nitric oxide, induced during bacterial phagocytosis, using a metalloprotein–gold nanoparticle conjugate [PDF]

, 2017
Nitric oxide (NO) plays an essential role within the immune system since it is involved in the break-down of infectious agents such as viruses and bacteria.
Gavrilovic, Jelena, Leggett, Richard, Marín, Maria J., Russell, David A., Thomas, Paul   +4 more
core   +1 more source

Organic and Inorganic Pollutants, Oxidative Stress Biomarkers, and Electrophoretic Protein Profiles in an Endangered Thresher Shark (Alopias vulpinus) From Southeastern Brazil: A Case Study

Environmental Toxicology, EarlyView.
ABSTRACT A comprehensive screening of different environmental contaminants (total metals, thermostable metal fractions associated with detoxification, and persistent organic pollutants) was conducted in an endangered common thresher shark (Alopias vulpinus ) individual incidentally captured in southeastern Brazil.
Sidney Fernandes Sales Junior, Amanda Pontes Lopes, Heloíse Martins de Souza, Regina Fonseca, Enrico Mendes Saggioro, Francielli Monteiro Casanova, Kamila Cezar Gramlich, Tatiana Dillenburg Saint'Pierre, Carlos German Massone, Renato Carreira, Rachel Ann Hauser‐Davis   +10 more
wiley   +1 more source

The Study Of The Levels Of Metalloproteinases, Cytokines And Lymphocyte Activation Markers In Seminal Plasma Of Men, Depending On Fertility [PDF]

, 2018
The study of the concentration of metalloproteinases, pro- and anti-inflammatory cytokines, lymphocyte activation markers in seminal plasma of men with oligosymptomatic forms of chronic inflammation of the urogenital tract (CIUT), depending on the ...
Matyucha, L. (Larysa), Tsiporenko, S. (Serhii)   +1 more
core   +2 more sources