Results 71 to 80 of about 21,893 (312)

Two-stage binding of mitochondrial ferredoxin-2 to the core iron-sulfur cluster assembly complex

Nature Communications
Iron-sulfur (FeS) protein biogenesis in eukaryotes begins with the de novo assembly of [2Fe-2S] clusters by the mitochondrial core iron-sulfur cluster assembly (ISC) complex.
Ralf Steinhilper, Linda Boß, Sven-A. Freibert, Vinzent Schulz, Nils Krapoth, Susann Kaltwasser, Roland Lill, Bonnie J. Murphy   +7 more
doaj   +1 more source

Cyanophenylalanine as an Infrared Probe for Iron–Sulfur Cluster Redox State in Multicenter Metalloenzymes

ChemBioChem, EarlyView.
The noncanonical amino acid, cyanophenylalanine, is genetically inserted close to iron–sulfur clusters of either spinach ferredoxin or iron–iron hydrogenase, and functions as an infrared spectroscopic reporter for changes in cluster redox state.
Zehui Duan, Jiaao Wei, Stephen B. Carr, Miguel Ramirez, Rhiannon M. Evans, Philip A. Ash, Patricia Rodriguez‐Macia, Amit Sachdeva, Kylie A. Vincent   +8 more
wiley   +1 more source

Evidence for a metalloprotein stucture of plasma membrane 5' -nucleotidase [PDF]

, 1984
To point out the metalloprotein structure of bovine liver plasma membrane 5'-nucleotidase we studied the inhibition mechanism of the purified enzyme by EDTA: this apparently non-competitive inhibition seems to be dependent on EDTA concentration, pH ...
Bernard, Serge, Duflos, Yves, Harb, Jean, Meflah, Khaled   +3 more
core   +1 more source

A de novo designed metalloprotein displays variable thermal stability and binding stoichiometry with transition metal ions

ChemBioChem, Accepted Article.
Metal‐binding selectivity in natural proteins is determined by multiple factors such as the protein’s structure, metal concentration within cellular compartments and the presence of metallochaperones. The in vitro selectivity of proteins for transition metal ions is largely governed by the Irving‐Williams series, that states protein‐metal complex ...
Britt Rooijakkers, Gaya Verhagen, Anneloes Cramer-Blok, Ed Zuidinga, Aimee Lynn Boyle   +4 more
wiley   +1 more source

Surface Immobilized His-tagged Azurin as a Model Interface for the Investigation of Vectorial Electron Transfer in Biological Systems [PDF]

, 2015
A model system for the electrochemical investigation of vectorial electron transfer in biological systems was designed, assembled and characterized. Gold electrodes, functionalized with a -OCH3 terminated, aromatic self-assembled monolayer, were used as ...
Berto, Marcello, Borsari, Marco, Bortolotti, Carlo Augusto, Casalini, Stefano, DI ROCCO, Giulia, Facci, Paolo, Farinola, Gianluca M., Kovtun, Alessandro, Liscio, Andrea, Operamolla, Alessandra   +9 more
core   +1 more source

Electroenzymatic CO2 Reduction Using Formate Dehydrogenase: Direct and Mediated Catalysis

ChemElectroChem, EarlyView.
Formate dehydrogenase from Desulfovibrio desulfuricans (DdFDH) demonstrates the ability to reversibly catalyze the electrochemical reduction of CO2 into formate, offering a potential pathway for CO2 mitigation and production of value‐added compounds.
Navendu Paul, Isabel Moura, Luísa B. Maia, Cristina M. Cordas, Jose J. G. Moura   +4 more
wiley   +1 more source

Role for inflammatory markers in predicting right ventricular failure in mechanical assist device recipients

ESC Heart Failure, EarlyView.
Abstract Right ventricular failure (RVF) is a common complication following left ventricular assist device (LVAD) implantation and increases patient morbidity and mortality. Due to the complex and limited understanding of RVF pathophysiology, efforts to prognosticate RVF after LVAD have been challenging.
Abdul‐Fatawu Osman, Shane S. Scott, Ebubechukwu O. Ezeh, Evans Osuji, Israel O. Ailemen, Mohamed H. Derbala, Salil Kumar, Asvin M. Ganapathi, Daniel B. Sims, Ashrith Guha, Bryan A. Whitson, Sakima A. Smith   +11 more
wiley   +1 more source

A haloarchaeal ferredoxin electron donor that plays an essential role in nitrate assimilation [PDF]

, 2011
In the absence of ammonium, many organisms, including the halophilic archaeon Haloferax volcanii DS2 (DM3757), may assimilate inorganic nitrogen from nitrate or nitrite, using a ferredoxin-dependent assimilatory NO3-/NO2- reductase pathway.
Bonete, Mari­a José, Butt, Julea N., Gates, Andrew J., Martínez‑Espinosa, Rosa María, Richardson, David J., Zafrilla, Basilio   +5 more
core   +1 more source

Nitric oxide biosensor uncovers diminished ferrous iron-dependency of cultured cells adapted to physiological oxygen levels

Redox Biology, 2022
Iron is an essential metal for cellular metabolism and signaling, but it has adverse effects in excess. The physiological consequences of iron deficiency are well established, yet the relationship between iron supplementation and pericellular oxygen ...
Gulsah Sevimli, Matthew J. Smith, Tuba Akgul Caglar, Şükriye Bilir, Melike Secilmis, Hamza Y. Altun, Esra N. Yigit, Fan Yang, Thomas P. Keeley, Roland Malli, Gürkan Öztürk, Giovanni E. Mann, Emrah Eroglu   +12 more
doaj  

Hemoglobin‐Related Biomaterials and their Applications

Advanced NanoBiomed Research, 2023
Hemoglobin (Hb) is a physiological oxygen‐transport metalloprotein present in the red blood cells. With the in‐depth study, many functions of Hb are developed, and kinds of Hb‐related biomaterials are applied for biomedical therapeutics in the past ...
Shaobing Li, Wei Sun, Min Ouyang, Bo Yu, Yan Chen, Yupeng Wang, Dongfang Zhou   +6 more
doaj   +1 more source