Results 281 to 290 of about 231,111 (308)

Matrix metalloproteinases and atherosclerosis

Current Atherosclerosis Reports, 2004
Atherosclerosis is a major cause of coronary heart disease, and matrix metalloproteinases (MMPs) play an important role in atherosclerosis by degrading the extracellular matrix, which results in cardiovascular remodeling. Recent studies have identified enhanced expression of MMPs in the atherosclerotic lesion and their contribution to weakening of the ...
Noboru, Watanabe, Uichi, Ikeda
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The Matrix Metalloproteinases and Their Inhibitors

American Journal of Respiratory Cell and Molecular Biology, 1992
Abstract A number of metalloproteinases that degrade the extracellular matrix of connective tissues and two specific tissue inhibitors of metalloproteinases (TIMPs) have now been isolated, characterized, and cloned. Comparison of the enzyme sequences has allowed the delineation of domain structures, and initial studies have been ...
G, Murphy, A J, Docherty
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Expression of Metalloproteinases and Metalloproteinase Inhibitor in Human Arthritic Synovium

Arthritis & Rheumatism, 1991
AbstractThe expression of messenger RNA encoding neutral metalloproteinases and the tissue inhibitor of metalloproteinases (TIMP) in human arthritic synovium was evaluated in situ, using RNA probes. Interstitial collagenase and stromelysin were expressed by synovial lining cells in patients with active rheumatoid arthritis (RA).
openaire   +2 more sources

Matrix metalloproteinases and matrix metalloproteinase inhibitors in lung cancer

Seminars in Oncology, 2002
Preclinical studies have provided evidence that matrix metalloproteinases (MMPs), a family of zinc-containing proteolytic enzymes, facilitate tumor invasion, the establishment of metastases, and the promotion of tumor-related angiogenesis. Matrix metalloproteinase inhibitors (MMPIs) have been shown to inhibit tumor growth and dissemination in ...
openaire   +2 more sources

Upregulation of matrix metalloproteinase 9 (MMP9)/tissue inhibitor of metalloproteinase 1 (TIMP1) and MMP2/TIMP2 ratios may be involved in lipopolysaccharide-induced acute lung injury

Journal of International Medical Research, 2020
Bizhen Zhu, Huixuan SHI, Guobing Chen
exaly  

Matrix metalloproteinase-2, membranous type 1 matrix metalloproteinase, and tissue inhibitor of metalloproteinase-2 expression in ectopic and eutopic endometrium

Fertility and Sterility, 2002
Ji Young Lee, Hye-Sung Moon, Mi Hye Park
exaly  

The validation of matrix metalloproteinase-9 mRNA gene expression as a predictor of outcome in patients with metastatic gastric cancer

Annals of Oncology, 2012
Ralf-Dieter Hofheinz, S-E Al-Batran, N Homann   +2 more
exaly  

Matrix Metalloproteinase 9 Testing in Dry Eye Disease Using a Commercially Available Point-of-Care Immunoassay

Ophthalmology, 2016
Elisabeth Messmer, Anselm Kampik
exaly  

The Impact of Differential Expression of Extracellular Matrix Metalloproteinase Inducer, Matrix Metalloproteinase-2, Tissue Inhibitor of Matrix Metalloproteinase-2 and PDGF-AA on the Chronicity of Venous Leg Ulcers

European Journal of Vascular and Endovascular Surgery, 2006
Sherif Sultan, Niamh Hynes, G Avalos
exaly  

Membrane-Type-2 Matrix Metalloproteinase Can Initiate the Processing of Progelatinase A and is Regulated by the Tissue Inhibitors of Metalloproteinases

FEBS Journal, 1997
Georgina S. Butler, Susan J Atkinson, S J Atkinson   +2 more
exaly