Results 41 to 50 of about 215,931 (289)

Allelic and Genotypic Distribution of MMP13-77 A/G Polymorphism in Salvadoran Children With and Without Caries

Clinics and Practice
Background/Objectives: Polymorphisms in metalloproteinases (MMPs) have the potential to be probable genetic biomarkers of dental caries. The aim of this study was to evaluate the distribution of the MMP13 A/G rs2252070 single nucleotide polymorphism (SNP)
Wendy Escobar-González, Jorge Alegría-Torres, Yolanda Terán-Figueroa, Vianney Castañeda-Monroy, Aurelio Álvarez-Vargas, Carlo Eduardo Medina-Solís, Nuria Patiño-Marín   +6 more
doaj   +1 more source

Perfil de proteases de lesões cutâneas experimentais em camundongos tratadas com a lectina isolada das sementes de Canavalia brasiliensis Proteases profile of skin wounds treated with lectin from Canavalia brasiliensis seeds

Ciência Rural, 2009
O objetivo deste estudo foi determinar o perfil de proteases em lesões cutâneas experimentais tratadas com a lectina isolada das sementes da Canavalia brasiliensis (ConBr) livre e conjugada com o seu açúcar específico.
Flávio de Oliveira Silva, Rosângela Vidal de Souza Araújo, Giuliana Viegas Schirato, Edson Holanda Teixeira, Mário Ribeiro de Melo Júnior, Benildo de Sousa Cavada, José Luiz de Lima-Filho, Ana Maria dos Anjos Carneiro-Leão, Ana Lúcia Figueiredo Porto   +8 more
doaj   +1 more source

CCAAT/enhancer binding protein β expression is increased in the brain during HIV-1-infection and contributes to regulation of astrocyte tissue inhibitor of metalloproteinase-1 [PDF]

, 2011
Human immunodeficiency virus (HIV)-1-associated neurocognitive disorders (HAND) associated with infection and activation of mononuclear phagocytes (MP) in the brain, occur late in disease. Infected/activated MP initiate neuroinflammation activating glial
Abraham, Akira, Alberini, Albertini, Borjabad, Brambilla, Brambilla, Bugno, Cardinaux, Chaillan, Chen, Clark, Cortes-Canteli, Crocker, Dean, Dean, Dhar, Ejarque-Ortiz, Fassina, Faulkner, Ferrari, Ferrari, Gardner, Gardner, Gris, Heales, Herrmann, Hornebeck, Jaworski, Jourquin, La Fleur, Laird, Lindl, Liu, Lorenzl, Lorenzl, Lorenzl, Manthrope, Menard, Nadeau, Oberheim, Ould-yahoui, Pagenstecher, Panenka, Phillips, Rivera, Sandhir, Sears, Sofroniew, Sofroniew, Sterneck, Suryadevara, Yadav, Yong, Yukawa   +54 more
core   +1 more source

Association Between Plasma ADAMTS-7 Levels and Diastolic Dysfunction in Patients with Type 2 Diabetes Mellitus

Medicina
A disintegrin and metalloproteinase with thrombospondin motifs-7 (ADAMTS-7) belongs to the family of metalloproteinases that contributes to tissue homeostasis during morphogenesis and reproduction. These metalloproteinases regulate various cell functions
Asimina Ganotopoulou, Emmanouil Korakas, Loukia Pliouta, Aikaterini Kountouri, Sotirios Pililis, Stamatios Lampsas, Ignatios Ikonomidis, Loukianos S. Rallidis, Athanasia Papazafiropoulou, Andreas Melidonis, Vaia Lambadiari   +10 more
doaj   +1 more source

Lonidamine Causes Inhibition of Angiogenesis-Related Endothelial Cell Functions

Neoplasia: An International Journal for Oncology Research, 2004
The aim of this study was to assess whether lonidamine (LND) interferes with some steps in angiogenesis progression. We report here, for the first time, that LND inhibited angiogenic-related endothelial cell functions in a dose-dependent manner (1-50 μg ...
Donatella Del Bufalo, Daniela Trisciuoglio, Marco Scarsella, Giulia D'Amati, Antonio Candiloro, Angela Iervolino, Carlo Leonetti, Gabriella Zupi   +7 more
doaj   +1 more source

An Analysis of the Content of Metalloproteinases in the Intestinal Wall of Patients with Crohn’s Disease

Life, 2023
One of the inflammatory bowel diseases is Crohn’s disease. Although this term has been used in the medical community since 1932, a significant increase in the number of publications occurs at the end of the 20th century and the beginning of the 21st ...
Grzegorz Chrzanowski, Grzegorz Pasternak, David Aebisher, Klaudia Dynarowicz, Angelika Myśliwiec, Dorota Bartusik-Aebisher, Barbara Sosna, Grzegorz Cieślar, Aleksandra Kawczyk-Krupka, Rafał Filip   +9 more
doaj   +1 more source

Pyrone-based inhibitors of metalloproteinase types 2 and 3 may work as conformation-selective inhibitors. [PDF]

, 2011
Matrix metalloproteinases are zinc-containing enzymes capable of degrading all components of the extracellular matrix. Owing to their role in human disease, matrix metalloproteinase have been the subject of extensive study.
de Oliveira, César AF, Durrant, Jacob D, McCammon, J Andrew   +2 more
core   +1 more source

A Strong Decrease in TIMP3 Expression Mediated by the Presence of miR-17 and 20a Enables Extracellular Matrix Remodeling in the NSCLC Lesion Surroundings

Frontiers in Oncology, 2019
Background: Lung cancer is one of the most common causes of death worldwide with a relatively high fatality rate and a mean 5-years survival of about 18%.
Karolina H. Czarnecka, Karolina H. Czarnecka, Bartosz Szmyd, Magda Barańska, Marcin Kaszkowiak, Jacek Kordiak, Adam Antczak, Dorota Pastuszak-Lewandoska, Ewa Brzeziańska-Lasota   +8 more
doaj   +1 more source

LTD4 and TGF-β1 induce the expression of metalloproteinase-1 in chronic rhinosinusitis via a cysteinyl leukotriene receptor 1-related mechanism [PDF]

, 2016
A
Bachert, Claus, Claeys, Cindy, Holtappels, Gabriële, Perez Novo, Claudina, Pezato, Rogerio   +4 more
core   +2 more sources

Zymography of Metalloproteinases

Current Protocols in Protein Science, 2003
AbstractZymography is an electrophoretic technique enabling visualization of the number and approximate size of peptidases in a sample on the basis of their hydrolysis of a protein substrate within the gel. The technique is particularly useful for analyzing the peptidase composition of complex biological samples because visualization depends directly ...
Troeberg, L, Nagase, H
openaire   +2 more sources