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Bioinformatics of Metalloproteins and Metalloproteomes [PDF]
Molecules, 2020 Trace metals are inorganic elements that are required for all organisms in very low quantities. They serve as cofactors and activators of metalloproteins involved in a variety of key cellular processes. While substantial effort has been made in experimental characterization of metalloproteins and their functions, the application of bioinformatics in ...
Ashraf Brik
exaly +5 more sources
Metalloproteins in the Biology of Heterocysts [PDF]
Life, 2019 Cyanobacteria are photoautotrophic microorganisms present in almost all ecologically niches on Earth. They exist as single-cell or filamentous forms and the latter often contain specialized cells for N2 fixation known as heterocysts. Heterocysts arise from photosynthetic active vegetative cells by multiple morphological and physiological rearrangements
Enrico Schleiff
exaly +8 more sources
Design of functional metalloproteins [PDF]
Nature, 2009 Metalloproteins catalyse some of the most complex and important processes in nature, such as photosynthesis and water oxidation. An ultimate test of our knowledge of how metalloproteins work is to design new metalloproteins. Doing so not only can reveal hidden structural features that may be missing from studies of native metalloproteins and their ...
Yi Lu
exaly +6 more sources
NMR studies of metalloproteins [PDF]
, 2011 Metalloproteins represent a large share of the proteomes, with the intrinsic metal ions providing catalytic, regulatory, and structural roles critical to protein functions.
Li, H, Sun, H
core +6 more sources
Isolation of Acidic, Basic and Neutral Metalloproteins by QPNC-PAGE [PDF]
, 2010 A standard protocol for isolating metalloproteins in complex biological samples is presented using quantitative preparative native continuous polyacrylamide gel electrophoresis (QPNC ...
Bernd Kastenholz, David E. Garfin
core +4 more sources
Microcontact printing of metalloproteins [PDF]
Synthetic Metals, 2005 The morphological investigation by scanning probes techniques, and especially Atomic Force Microscopy (AFM) allow to measure the surface roughness of immobilized proteins with unequalled vertical spatial resolution. This is particularly important, since the biological role of proteins is closely related to their physiological folding architectures.
BIASCO, Adriana Lucia Angela +4 more
openaire +5 more sources
Hepatology, EarlyView., 2022 CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli +13 more
wiley +1 more source
Quantitative Preparative Native Continuous Polyacrylamide Gel Electrophoresis (QPNC-PAGE) [PDF]
, 2008 QPNC-PAGE, or quantitative preparative native continuous polyacrylamide gel electrophoresis, is a high-resolution technique applied in biochemistry and bioinorganic chemistry to separate proteins by isoelectric point.
Bernd Kastenholz
core +2 more sources
Computational Treatment of Metalloproteins [PDF]
The Journal of Physical Chemistry B, 2015 Metalloproteins present a considerable challenge for modeling, especially when the starting point is far from thermodynamic equilibrium. Examples include formidable problems such as metalloprotein folding and structure prediction upon metal addition, removal, or even just replacement; metalloenzyme design, where stabilization of a transition state of ...
Nechay, Michael R +2 more
openaire +5 more sources
Great metalloclusters in enzymology [PDF]
, 2002 Metallocluster-containing enzymes catalyze some of the most basic redox transformations in the biosphere. The reactions catalyzed by these enzymes typically involve small molecules such as N2, CO, and H2 that are used to generate both chemical building ...
Rees, Douglas C.
core +1 more source