Decorin Is a Zn2+ Metalloprotein [PDF]
Journal of Biological Chemistry, 1999 Decorin is ubiquitously distributed in the extracellular matrix of mammals and a member of the proteoglycan family characterized by a core protein dominated by leucine-rich repeat motifs. We show here that decorin extracted from bovine tissues under denaturing conditions or produced in recombinant "native" form by cultured mammalian cells has a high ...
Magnus Höök +4 more
openaire +2 more sources
Crystal structures of the NO sensor NsrR reveal how its iron-sulfur cluster modulates DNA binding
Nature Communications, 2017 NsrR is a bacterial transcriptional regulator that acts as a nitric oxide (NO) sensor. Here, the authors present the crystal structure of NsrR, which reveals an unusual Fe-S cluster coordination and explains how NO exposure leads to the degradation of ...
Anne Volbeda +7 more
doaj +1 more source
L-Edge Spectroscopy of Dilute, Radiation-Sensitive Systems Using a Transition-Edge-Sensor Array [PDF]
, 2017 We present X-ray absorption spectroscopy and resonant inelastic X-ray scattering (RIXS) measurements on the iron L-edge of 0.5 mM aqueous ferricyanide.
Betty A. Young +28 more
core +3 more sources
mBio, 2022 Engineering plants to synthesize nitrogenase and assimilate atmospheric N2 will reduce crop dependency on industrial N fertilizers. This technology can be achieved by expressing prokaryotic nitrogen fixation gene products for the assembly of a functional
Xi Jiang +8 more
doaj +1 more source
Modules identification in gene positive networks of hepatocellular carcinoma using pearson agglomerative method and Pearson cohesion coupling modularity [PDF]
, 2012 In this study, a gene positive network is proposed based on a weighted undirected graph, where the weight represents the positive correlation of the genes.
Gao, Zhiwei, Hu, Jinyu
core +3 more sources
The Stereochemical Basis of the Genetic Code and the (Mostly) Autotrophic Origin of Life
Life, 2014 Spark-tube experiments and analysis of meteorite contents have led to the widespread notion that abiotic organic molecules were the first life components.
Juan C. Fontecilla-Camps
doaj +1 more source
Establishing the entatic state in folding metallated Pseudomonas aeruginosa azurin [PDF]
, 2007 Understanding how the folding of proteins establishes their functional characteristics at the molecular level challenges both theorists and experimentalists.
Adman +25 more
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Electronic structure and correlations of vitamin B12 studied within the Haldane-Anderson impurity model [PDF]
, 2015 We study the electronic structure and correlations of vitamin B12 (cyanocobalamine) by using the framework of the multi-orbital single-impurity Haldane-Anderson model of a transition-metal impurity in a semiconductor host. The parameters of the effective
Bulut, Nejat +2 more
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Importance of many body effects in the kernel of hemoglobin for ligand binding [PDF]
Phys. Rev. Lett. 110, 106402 (2013), 2012 We propose a mechanism for binding of diatomic ligands to heme based on a dynamical orbital selection process. This scenario may be described as bonding determined by local valence fluctuations. We support this model using linear-scaling first-principles calculations, in combination with dynamical mean-field theory, applied to heme, the kernel of the ...
arxiv +1 more source
Probing a Complex of Cytochromecand Cardiolipin by Magnetic Circular Dichroism Spectroscopy: Implications for the Initial Events in Apoptosis [PDF]
, 2011 Oxidation of cardiolipin (CL) by its complex with cytochrome c (cyt c) plays a crucial role in triggering apoptosis. Through a combination of magnetic circular dichroism spectroscopy and potentiometric titrations, we show that both the ferric and ferrous
Armstrong F. A. +42 more
core +1 more source