Results 71 to 80 of about 22,892 (210)
mBio, 2017 Copper (Cu) ions serve as catalytic cofactors to drive key biochemical processes, and yet Cu levels that exceed cellular homeostatic control capacity are toxic. The underlying mechanisms for Cu toxicity are poorly understood.
Sarela Garcia-Santamarina +4 more
doaj +1 more source
Periodontology 2000, EarlyView.Abstract Peri‐implant diseases are dysbiosis‐mediated inflammatory disorders that occur in susceptible hosts. Antimicrobials and immunomodulatory agents therefore might be pertinent as adjunctive measures in the treatment of such disorders. The aim of this narrative review was to examine the existing evidence and assess the effectiveness of emerging ...
Alberto Monje +3 more
wiley +1 more source
Functional and structural mimics of superoxide dismutase enzymes [PDF]
, 2008 Superoxide dismutase (SOD) enzymes form important defence line in living organisms. Through a dismutation reaction they transform the highly reactive superoxide radical ion to oxygen and hydrogen peroxide.
Pálinkó, István
core
Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 2, Page 620-632, February 2026.ABSTRACT Metallothioneins (MTLs) are small, cysteine‐rich proteins known for their ability to bind metal ions and exhibit flexible, disordered structures. The structural and functional characteristics of metallothionein I (MTL‐1) from Caenorhabditis elegans were investigated, focusing on its behavior in both metal free (MTL‐1 Apo) and metal‐bond states
Nilvea Ramalho de Oliveira +4 more
wiley +1 more source
, 2017 Zero-field splitting (ZFS) parameters are fundamentally tied to the geometries of metal ion complexes. Despite their critical importance for understanding the magnetism and spectroscopy of metal complexes, they are not routinely available through general
Belvin, Carina +9 more
core +1 more source
Metalloprotein Crystallography: More than a Structure [PDF]
, 2015 Metal ions and metallocofactors play important roles in a broad range of biochemical reactions. Accordingly, it has been estimated that as much as 25–50% of the proteome uses transition metal ions to carry out a variety of essential functions.
Bowman, Sarah E. J. +2 more
core +1 more source
eLife, 2016 The metallocofactor involved in fixing nitrogen is not a rigid scaffold, as was previously thought.
Percival Yang-Ting Chen +2 more
doaj +1 more source
Synthesis and evaluation of a novel ionophore based on a thiacalix[4]arene derivative bearing imidazole units [PDF]
, 2014 O-Alkylation of the flexible thiacalix[4]arene 1 with 2-chloromethyl-1-methyl-1H-imidazole 2 in the presence of Na₂CO₃ or K₂CO₃ afforded mono-O-alkylation product 3 in 29–51% yield, along with recovery of the starting compound.
Elsegood, Mark R. J. +8 more
core +3 more sources
ChemMedChem, Volume 21, Issue 1, January 2026.A set of three cysteine‐derived hydroxamic acids were synthesized and evaluated for human gloxalase‐1 inhibition and ferroptosis induction activities. Among them, compound 2 exhibited a potent inhibitory effect against human glyoxalase‐1 and induced ferroptosis in non‐small cell lung cancer cell lines, increasing reactive oxygen species production and ...
Josué Martínez‐Miranda +7 more
wiley +1 more source
Magnetochemistry, 2020 The study of cellular machineries responsible for the iron–sulfur (Fe–S) cluster biogenesis has led to the identification of a large number of proteins, whose importance for life is documented by an increasing number of diseases linked to them.
Mario Piccioli
doaj +1 more source