Results 41 to 50 of about 77,240 (295)
Only a small number of genes are known direct targets of the zinc-responsive transcription factor MTF1; therefore, the aim of this study was to gain a more complete understanding of the MTF-1 regulated zinc-responsive component of the transcriptome.
J. E. Hardyman+7 more
semanticscholar +1 more source
Correlation between biomarkers of exposure, effect and potential harm in the urine of electronic cigarette users. [PDF]
ObjectivesTo determine if urinary biomarkers of effect and potential harm are elevated in electronic cigarette users compared with non-smokers and if elevation correlates with increased concentrations of metals in urine.Study design and settingThis was a
Bates, Steve M+8 more
core
Bacterial metallothioneins [PDF]
Abstract Heavy metals are found in all living organisms where, as indispensable microelements (e.g. zinc, iron, copper), are involved in endless metabolic processes. However, living organisms are also at a risk of exposure to highly toxic metals, including cadmium or lead, which do not play any physiological role.
Agnieszka Mierek-Adamska+3 more
openaire +2 more sources
Mammalian Metallothionein-2A and Oxidative Stress
Mammalian metallothionein-2A (MT2A) has received considerable attention in recent years due to its crucial pathophysiological role in anti-oxidant, anti-apoptosis, detoxification and anti-inflammation.
Xue Ling+7 more
semanticscholar +1 more source
Zinc is an essential nutrient for humans; however, a sensitive biomarker to assess zinc status has not been identified. The objective of this systematic review was to compile and assess studies that determined zinc transporter and/or metallothionein ...
Stephen R. Hennigar+2 more
semanticscholar +1 more source
The increasing efflux on a large scale of organic contaminants holding endocrine disrupting activity from sewage treatment plants produces detrimental biological effects to various fish species.
Michael Niederwanger+8 more
doaj +1 more source
The Evolution of Insect Metallothioneins [PDF]
ABSTRACTMetallothioneins (MTs) are a family of cysteine-rich metal-binding proteins that are important in the chelating and detoxification of toxic heavy metals. Until now, the short length and the low sequence complexity of MTs has hindered the possibility of any phylogenetic reconstruction, hampering the study of their evolution.
Haosu Cong+5 more
openaire +3 more sources
The Role of Metallothionein in Oxidative Stress
Free radicals are chemical particles containing one or more unpaired electrons, which may be part of the molecule. They cause the molecule to become highly reactive.
B. Ruttkay-Nedecky+8 more
semanticscholar +1 more source
Metallothionein in Brain Disorders
Metallothioneins are a family of proteins which are able to bind metals intracellularly, so their main function is to regulate the cellular metabolism of essential metals.
Daniel Juárez-Rebollar+3 more
semanticscholar +1 more source
The toxicity of cadmium and resulting hazards for human health [PDF]
Cadmium (Cd) has been in industrial use for a long period of time. Its serious toxicity moved into scientific focus during the middle of the last century.
Brandenburg, Paul+6 more
core +2 more sources