Results 91 to 100 of about 9,301 (237)

PharmVar GeneFocus: NAT2—Genetic Variation and Updated Nomenclature

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 859-871, April 2026.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human N‐acetyltransferase 2 (NAT2) gene. NAT2 metabolizes several clinically used drugs including isoniazid, hydralazine, amifampridine, procainamide, and sulfonamides such as dapsone, and also some highly carcinogenic arylamines.
Georgia Papanikolaou, Estella S. Poloni, José A.G. Agúndez, Raquel L.F. Teixeira, Erin C. Boone, Adalberto Rezende Santos, Michelle Whirl‐Carrillo, Katrin Sangkuhl, Teri E. Klein, Mariam R. Habil, Giannoulis Fakis, Rodney F. Minchin, David W. Hein, Sotiria Boukouvala, Andrea Gaedigk   +14 more
wiley   +1 more source

Medication use in pregnancy: a cross-sectional, multinational web-based study [PDF]

, 2014
Objectives: Intercountry comparability between studies on medication use in pregnancy is difficult due to dissimilarities in study design and methodology. his study aimed to examine patterns and factors associated with medications use in pregnancy from a
Bjornsdottir, I., Drozd, M., Gjergja Juraski, R., Hameen-Anttila, K., Juch, H., Kennedy, D., Lupattelli, A., Mardby, A. C., Moretti, M. E., Nordeng, H., Odalovic, M., Panchaud, A., Passier, A., Rieutord, A., Rudolf, G., Spigset, O., Twigg, M. J., Zagorodnikova, K.   +17 more
core   +5 more sources

Elevated Polyreactive Immunoglobulin G in Immune‐Mediated Liver Injuries With the Need for Immunosuppressive Therapy

Liver International, Volume 46, Issue 4, April 2026.
ABSTRACT Background & Aims The distinction of drug‐induced liver injury (DILI), drug‐induced autoimmune‐like hepatitis (DI‐ALH), and autoimmune hepatitis (AIH) can be challenging due to overlapping clinical characteristics. Recently, polyreactive immunoglobulin G (pIgG) was identified as a novel biomarker in AIH.
Theresa Kirchner, George N. Dalekos, Kalliopi Zachou, Mercedes Robles‐Díaz, Raúl J. Andrade, Marcial Sebode, Ansgar Lohse, Maciej K. Janik, Piotr Milkiewicz, Mirjam Kolev, Nasser Semmo, Tony Bruns, Tom Jg. Gevers, Benedetta Terziroli Beretta‐Piccoli, Heiner Wedemeyer, Elmar Jaeckel, Richard Taubert, Bastian Engel, pIgG study group   +18 more
wiley   +1 more source

Acute pain in adults admitted to the emergency room: development and implementation of abbreviated guidelines. [PDF]

, 2007
AIM: Although acute pain is frequently reported by patients admitted to the emergency room, it is often insufficiently evaluated by physicians and is thus undertreated.
Blanc, C., Buclin, T., Decosterd, I., Givel, J.C., Hugli, O., Mouhsine, E., Tamchès, E., Yersin, B.   +7 more
core  

Noramidopyrine (Metamizol) and acute interstitial nephritis [PDF]

Nephrology Dialysis Transplantation, 1998
amount ingested: 30 g). On admission his serum creatiIntroduction nine and blood urea nitrogen (BUN) were 4.5 mg/dl and 39 mg/dl respectively. Urinalysis revealed 30 mg/dl Noramidopyrine (Metamizol ) is a non-narcotic, protein, 3+ positive for blood (dipstick), and 5–10 analgesic and antipiretic pyrazolone derivative which red blood cells and 3–5 white
V. Berruti, G. Salvidio, S. Saffioti, PONTREMOLI, ROBERTO, O. Arnone, M. Giannoni, GARIBOTTO, GIACOMO   +6 more
openaire   +3 more sources

Efek Proteksi Otak Metamizol Intravena Sebagai Farmakologik Hipotermi Terhadap Suhu Inti Dan Kadar Interleukin-6 Pada Pasien Cedera Kepala Berat

Jurnal Neuroanestesi Indonesia, 2017
Latar Belakang dan Tujuan: Cedera kepala berat merupakan salah satu penyebab mortalitas dan morbiditas bagi pasien pasca trauma. Sirkulasi sitokin interleukin-6 (IL-6) pada cedera kepala berat dan proteksi otak dalam pengaturan suhu berhubungan dengan ...
Muhammad Erias, Ruli Herman Sitanggang, Tatang Bisri   +2 more
doaj   +1 more source

Assessment and evaluation of Chitosan‐Metamizole nanoparticles for the fracture healing and analgesic effect: Preclinical study in rat model

IET Nanobiotechnology, 2023
To assess and evaluate Chitosan‐Metamizole nanoparticles for fracture healing and analgesic potential, nanoparticles were formulated using the ionotropic gelation method.
Li Yin, Liyong Yuan, Chunling Peng, Qionghua Wang   +3 more
doaj   +1 more source

Outpatient Utilization Patterns of the Six Main ATC Drug Groups in Republic of Croatia, City of Zagreb, and Croatia Counties in 2004 [PDF]

, 2009
The aim of the study was to determine drug utilization according to Croatian counties, and to identify the causes of the possible between-county utilization variation.
Danijela Štimac, Ivan Vukušić, Josip Čulig, Mila Bucalić, Siniša Tomić, Zvonimir Šostar   +5 more
core   +1 more source

Integral UV Spectrophotometric Methods for Determination of Clopidogrel Bisulphate and Metamizole Sodium in Rinse Waters from Industrial Equipment

Spectroscopy Journal
In this paper, methods for the determination of clopidogrel bisulphate and metamizole sodium in rinse waters from industrial equipment, using multiwavelength UV spectrometry and the calculation of areas under curves, are proposed.
P. A. Nikolaychuk
semanticscholar   +1 more source

Impact of Thiazides and Fluoropyrimidines Interaction on Myelotoxicity and Other Adverse Events in Real‐World Practice: A Retrospective Cohort Study

Cancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Introduction The European Summary of Product Characteristics (SmPC) for 5‐FU warns of significant granulocyte decline when combined with thiazides, cyclophosphamide, or methotrexate, based on a 1981 cohort of 14 patients. Despite limited evidence, drug‐interaction checkers still flag this risk.
Gerard Ronda‐Roca, José Porcel‐Maleno, Mónica Lobo‐Palomar, Gustavo Centeno‐Soto, Ana Ruiz‐Casado, Belén Ruiz‐Antorán   +5 more
wiley   +1 more source