Results 71 to 80 of about 5,434 (205)

Synthesis, X‐Ray Analysis, Anticancer Activity, Computational, and in Silico Studies of New Thiophene Pyrazole Conjugates

ChemistryOpen, Volume 15, Issue 6, June 2026.
Two new thiophene–pyrazole derivatives, 8a and 8b, were synthesized from thiophene 3 precursor and fully characterized. The structure of 8a was confirmed by single‐crystal X‐ray diffraction, which revealed a nonplanar conformation stabilized by NH···O hydrogen bonding and weak intermolecular contacts.
Abdullatif Bin Muhsinah, Nabila A. Kheder, Ismail A. Elhaty, Yahia N. Mabkhot   +3 more
wiley   +1 more source

Metabolism and Drug-Drug Interaction Studies of Metamizole in Humans [PDF]

, 2021
Metamizole is a non-opioid analgesic with additional antipyretic and spasmolytic properties. It was introduced nearly 100 years ago, but due to a severe but rare side-effect agranulocytosis, it has been withdrawn from the market in several countries ...
Bachmann, Fabio
core  

[Adequacy of the safety of metamizole and agranulocytosis].

Atencion primaria, 2021
To analyze whether the drug safety update issued by the Spanish Agency of Medicines and Healthcare Products (AEMPS), dated October 30, 2018, on agranulocytosis and metamizole contains accurate and necessary information to protect patients from the presentation of this adverse reaction (AR) and if the official documentation of medicines containing ...
Garcia Del Campo C, Murcia Soler M, Martinez-Mir I, Palop Larrea V   +3 more
openaire   +2 more sources

Metamizole intolerance and bronchial asthma

Allergologia et Immunopathologia, 2002
Metamizole is one of the pyrazolone drugs used widely in Turkey. The aim of this survey was to determine the clinical features of metamizole intolerant patients and to find out if there was any difference between the ones with or without bronchial asthma.A total of 264 patients with metamizole intolerance were enrolled in the survey.
G, Karakaya, A F, Kalyoncu
openaire   +2 more sources

European Interdisciplinary Guidelines on Pain Management in Acute Pancreatitis: UEG, EPC, EDS, ESDO, EAGEN, ESPGHAN, ESGAR, and ESPCG Evidence‐Based Recommendations

United European Gastroenterology Journal, Volume 14, Issue 5, June 2026.
ABSTRACT Pain is often the presenting symptom of acute pancreatitis (AP) and has a prognostic significance, with poorly treated pain affecting patient outcomes. Despite this, there are currently no international recommendations for pain management in patients admitted with AP.
Sanjay Pandanaboyana, Cecilie Siggaard Knoph, Louise Kuhlmann, Patrice Forget, Esther Pogatzki‐Zahn, Wei Huang, Stefanos Bonovas, Daniele Piovani, Isabelle Scheers, Karina Cárdenas‐Jaén, Sara Regner, Asbjorn Mohr Drewes, on behalf of European Pain in Acute Pancreatitis Multidisciplinary Group, Maissam Abu‐El‐Haija, Jana Aulenkamp, Frank Bodewes, Stefan Bouwense, Roberto Cannella, Gabriele Capurso, Guralp Ceyhan, Enrique de‐Madaria, Sarah De Lucia, Ana Dugic, Ekin Demir, Enrique Domínguez‐Muñoz, Lucia Guilabert, Pramod Kumar Garg, Cheryl Hartzell, Peter Hegyi, Nejo Joseph, James Lucocq, Giovanni Marchegiani, Alessio Marchetti, Soeren Marsmann, Etna Masip, Vivek Peddakota, Manu Nayar, Sara Nikolic, Hanna Sternby, Jayanta Samanta, Sandeep Siddhi, Ajith Siriwardena, Vikesh Singh, Søren Schou Olesen, Grzegorz Oracz, Davor Stimac, Michael Wilschanski, Heiko Witt, John Windsor   +48 more
wiley   +1 more source

Cellulitis Developing After Intramuscular Metamizole Injection

, 2016
If the suitable technique is not used in intramuscular injection applications and the injection area is not detected correctly, complications may be observed.
Yazicioglu, Bahadir, Emrah Dost, Bahadir Yazicioglu, Onur Ozturk, Dost, Emrah, Ozturk, Onur   +5 more
core   +1 more source

Efek Proteksi Otak Metamizol Intravena Sebagai Farmakologik Hipotermi Terhadap Suhu Inti Dan Kadar Interleukin-6 Pada Pasien Cedera Kepala Berat

Jurnal Neuroanestesi Indonesia, 2017
Latar Belakang dan Tujuan: Cedera kepala berat merupakan salah satu penyebab mortalitas dan morbiditas bagi pasien pasca trauma. Sirkulasi sitokin interleukin-6 (IL-6) pada cedera kepala berat dan proteksi otak dalam pengaturan suhu berhubungan dengan ...
Muhammad Erias, Ruli Herman Sitanggang, Tatang Bisri   +2 more
doaj   +1 more source

Effect of chilled eye drops on postoperative pain sensation after phototherapeutic keratectomy: Randomised controlled clinical trial

Acta Ophthalmologica, Volume 104, Issue 4, Page 438-447, June 2026.
Abstract Purpose To analyse pain sensation after phototherapeutic keratectomy (PTK) using chilled eye drops or drops at room temperature during the early postoperative period. Methods Our randomised controlled, parallel‐group study conducted in the Department of Ophthalmology, Goethe‐University, Frankfurt (Main), Germany, with blinded participants and ...
Carolin Marion Kolb‐Wetterau, Julian Bucur, Marvin Lucas Biller, Petra Dávidová, Klemens Paul Kaiser, Kleopatra Varna‐Tigka, Ingo Schmack, Thomas Kohnen   +7 more
wiley   +1 more source

Cholangiocarcinoma in a central bearded dragon (Pogona vitticeps): A case report

Australian Veterinary Journal, Volume 104, Issue 6, Page 404-409, June 2026.
Cholangiocarcinoma is an uncommon malignant epithelial tumour of the biliary tract in reptiles and is rarely reported in central bearded dragons (Pogona vitticeps). This case report describes a 7‐year‐old male central bearded dragon in which a nonspecific coelomic opacity was incidentally detected during a routine clinical examination.
M Mikiewicz, K Paździor‐Czapula, I Otrocka‐Domagała   +2 more
wiley   +1 more source

Data Metamizole Pharmacokinetics Mice

Data concerning the following project/manuscript: Pharmacokinetics, efficacy, and safety of metamizole in C57BL/6J mice after subcutaneous injection and during voluntary oral self-intake Background Metamizole is a widely used analgesic in both human and ...
Glasenapp, Aylina, Bankstahl, Jens P., Glage, Silke, Parmar, Amisha R., Timartas, Derya, Hauser, Jana, Bankstahl, Marion, Kozlov, Andrey V., Bähre, Heike, Palme, Rupert   +9 more
core   +1 more source