Results 91 to 100 of about 8,395 (267)
Metamizol: schwerwiegende Nebenwirkungen – Update
, 2022 Bekannte schwerwiegende Nebenwirkungen von Metamizol sind das Auftreten einer Agranulozytose sowie einer hypotensiven Reaktion, insbesondere nach parenteraler Anwendung. Schon 2009 wies das BfArM daher bei steigenden Verordnungszahlen auf die Risiken von Metamizol hin.
Lübow, Anne Charlotte +2 more
openaire +2 more sources
Advanced Science, Volume 13, Issue 21, 13 April 2026.Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider +20 more
wiley +1 more source
Multimodal Cross‐Attentive Graph‐Based Framework for Predicting In Vivo Endocrine Disruptors
Advanced Science, Volume 13, Issue 21, 13 April 2026.A multimodal cross‐attentive graph neural network integrates molecular graphs with androgen and estrogen adverse outcome pathway (AOP)–anchored in vitro assay signals to predict in vivo endocrine disruption. By fusing information on Tier‐1 AOP logits with chemical structures, the framework achieves high accuracy and provides assay‐traceable ...
Eder Soares de Almeida Santos +6 more
wiley +1 more source
Kounis Syndrome Following Metamizole Infusion
Sakarya Medical Journal, 2016 Objective Kounis Syndrome (KS) is described as temporary vasospasm of coronary arteries after exposure to an allergen. It may present as severe chest pain, ST elevated or non-ST elevated myocardial infarction. Among factors causing KS are bee stings, all kinds of medications and food.
Ece, Yasemin +2 more
openaire +2 more sources
PharmVar GeneFocus: NAT2—Genetic Variation and Updated Nomenclature
Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 859-871, April 2026.The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human N‐acetyltransferase 2 (NAT2) gene. NAT2 metabolizes several clinically used drugs including isoniazid, hydralazine, amifampridine, procainamide, and sulfonamides such as dapsone, and also some highly carcinogenic arylamines.
Georgia Papanikolaou +14 more
wiley +1 more source
Metamizole intolerance and bronchial asthma
Allergologia et Immunopathologia, 2002 Metamizole is one of the pyrazolone drugs used widely in Turkey. The aim of this survey was to determine the clinical features of metamizole intolerant patients and to find out if there was any difference between the ones with or without bronchial asthma.A total of 264 patients with metamizole intolerance were enrolled in the survey.
G, Karakaya, A F, Kalyoncu
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European Journal of Pain, Volume 30, Issue 4, April 2026.ABSTRACT Background Inadequate postoperative pain management after lumbar discectomy may delay recovery, increase the risk of chronic pain, and prolong hospitalization. Effective analgesic strategies must balance pain control with minimal adverse effects.
Josephine Zachodnik +7 more
wiley +1 more source
Safety of the electroconvulsive therapy and amisulpride combination [PDF]
, 2014 BACKGROUND: Electroconvulsive therapy is frequently considered when pharmacotherapy is ineffective. In such cases the combination of the two treatment modalities are commonly used.
Gazdag Gábor László +3 more
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Analgesic prescribing in care home residents: how epidemiological studies may inform clinical practice [PDF]
, 2016 Care home residents are often frail with multiple comorbidities and cognitive impairment, most commonly caused by dementia. This population is under-represented in clinical trials, leading to a lack of valid and reliable evidence to inform clinicians ...
La Frenais, FL, Sampson, EL, Stone, P
core +1 more source