Results 91 to 100 of about 5,839 (199)

Influence of different excipients on the properties of hard gelatin capsules with metamizole sodium

Current Issues in Pharmacy and Medical Sciences, 2016
Metamizole is an effective non-opioid analgesic drug used in the treatment of acute and chronic pain. Due to induced potentially life-threatening blood disorders, metamizole was withdrawn from market in many parts of the world, however, it is one of the ...
Rogowska Magdalena, Iwaniak Karol, Polski Andrzej, Slawinska Karolina, Sobotka-Polska Karolina, Modrzewska Joanna, Poleszak Ewa   +6 more
doaj   +1 more source

Potential Cytoprotective and Anti-Apoptotic Effect of Metamizole Alone and in Combination with Cytostatic Drugs Observed In Vitro in Canine (D-17) and Human (U-2 OS) Osteosarcoma Cell Lines

Biomedicines
Metamizole (dipyrone) is still a frequently used drug in human and veterinary medicine, especially for pain relief, sometimes also in osteosarcoma treatment.
Dominik Poradowski, Aleksander Chrószcz, Radosław Spychaj, Vedat Onar   +3 more
doaj   +1 more source

The Uncertainties of Metamizole Use [PDF]

Clinical Pharmacology & Therapeutics, 2021
openaire   +2 more sources

Pharamacological properties of a classical analgesic agent ,Metamizole :past and present

Metamizole, a potent analgesic and antipyretic, has been effective in treating pain and fever but faces scrutiny due to its association with agranulocytosis, a serious reduction in white blood cells.
Sidick, Walliyat Temidire
core  

Abstracts from the 2026 Congress of the Scandinavian Society of Anesthesiology and Intensive Care Medicine, Reykjavik, Iceland, June 10–12, 2026

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 9, October 2026.
wiley   +1 more source

Evaluation of injectable metamizole utilization in children and adults in primary care

, 2020
Objective: Use of injectable metamizole in the outpatient setting is controversial due to safety concerns. We aimed to compare injectable metamizole prescribing patterns for children and adults with further evaluation of nationwide metamizole consumption

core   +1 more source

Hematological safety of metamizole: retrospective analysis of WHO and Swiss spontaneous safety reports

, 2015
Since the 1970s, the use of metamizole is controversial due to the risk of agranulocytosis. The aim of this study was to analyze individual case safety reports (ICSRs) of metamizole-associated hematological adverse drug reactions (ADRs).; International ...
Tramonti, Alexandra, Rätz Bravo, Alexandra E., Krähenbühl, Stephan, Blaser, Lea S., Haschke, Manuel, Egger, Pascal   +5 more
core   +1 more source

The effect of metoclopramide on the antinociceptive, locomotor and neurobehavioral effects of metamizole in mice

Macedonian Veterinary Review
Combining analgesic medications with distinct pharmacodynamics may result in effective analgesia and reduced adverse effects by lowering dosages of one or both medications. The objective was to investigate the nature of interactions of metoclopramide and
Zena Sattam Hamed, Khalid Ahmed Shaban, Ghada Abdul-Munem Faris   +2 more
doaj   +1 more source

Effects of Metamizole, 4-Methylaminoantipyrine, and 4-Aminoantipyrine on LX-2 Liver Cell Line Viability and Apoptosis

Molecules
Metamizole (dipyrone) is a non-opioid analgesic widely used in human and veterinary medicine, despite ongoing concerns about its safety due to risks such as agranulocytosis and potential hepatotoxicity.
Georgiana-Iulia Lupu, Emoke Pall, Mihai Cenariu, Monica Irina Nan, Sanda Andrei   +4 more
doaj   +1 more source

Dipyrone (metamizole)

, 2018
Dipyrone (metamizole) is a non-opioid analgesic commonly used in Germany, which can, in very rare cases, cause life-threatening agranulocytosis. The prescribing information calls for regular monitoring of the differential blood count in cases of long-term treatment.
Stamer, Ulrike M., Gundert-Remy, Ursula, Biermann, E., Erlenwein, Joachim, Meissner, W., Wirz, Stefan, Stammschulte, T.   +6 more
openaire   +1 more source