Results 61 to 70 of about 9,301 (237)

Acute renal failure and severe thrombocytopenia associated with metamizole

Saudi Journal of Kidney Diseases and Transplantation, 2014
Metamizole or dipyrone is a pyrazolone derivative that belongs to the non-steroidal anti-inflammatory drugs. Its main side-effect is hematological toxicity.
Maria Dolores Redondo-Pachon, Ricardo Enríquez, Ana Esther Sirvent, Isabel Millan, Alberto Romero, Francisco Amorós   +5 more
doaj   +1 more source

LC-QTOF MS screening of more than 1,000 licit and illicit drugs and their metabolites in wastewater and surface waters from the area of Bogotá, Colombia [PDF]

, 2015
A large screening of around 1,000 emerging contaminants, focused on licit and illicit drugs and their metabolites, has been made in urban wastewaters (both influent and effluent) and surface waters from the area of Bogotá, Colombia.
Bade, Richard, Bijlsma, Lubertus, Botero-Coy, Ana Maria, Bustos López, Martha Cristina, Hernandez, Felix, Ibáñez, Maria, Moncayo-Lasso, Alejandro, Rincón, Javier   +7 more
core   +1 more source

THE STUDY OF SOME PROMISING PHARMACEUTICAL COMPOSITIONS WITH UREASE INHIBITORY ACTIVITY FOR THE TUBERCULOSIS REACTIVATION PREVENTION [PDF]

Annals of Mechnikov's Institute, 2017
Introduction. The aim of the study was to study the ability to inhibit urease by some pharmaceutical compositions that are promising in the prevention of tuberculosis reactivation .
Bomko T.V., Martynov A.V., Nosalskaya T.N.   +2 more
doaj   +1 more source

Pain in IBD Patients: Very Frequent and Frequently Insufficiently Taken into Account. [PDF]

, 2016
Pain is a common symptom related to inflammatory bowel disease (IBD). In addition to abdominal pain, pain can also be an extraintestinal manifestation of IBD.
Ak, Melike, Biedermann, Luc, Fournier, Nicolas, Frei, Pascal, Fried, Michael, Müller-Mottet, Séverine, Pittet, Valerie, Rogler, Gerhard, Scharl, Michael, Scharl, Sylvie, Swiss IBD Cohort Study Group, Vavricka, Stephan, Zeitz, Jonas   +12 more
core   +4 more sources

Medication Safety in Intravenous Therapy: A Compatibility Study and Analysis of Reaction Products of Dihydralazine and Metamizole

Scientia Pharmaceutica, 2020
The pharmacotherapy of critically ill patients is challenging due to the variety of drugs that have to be applied. As the majority of pharmaceuticals must be administered intravenously because of the critical condition of the patients, the compatibility ...
Anna Katharina Koller, Oliver Fischer, Sabine Krebs, Markus R. Heinrich, Frank Dörje   +4 more
doaj   +1 more source

COX inhibiitorite nimesuliidi, paratsetamooli ja metamisooli toime aspiriiniresistentsete koronaarhaigete trombotsüütidele enne ja pärast aortokoronaarset šunteerimist [PDF]

, 2010
Koronaarhaigetel on täheldatud trombotsüütide suurenenud aktiveeritust. Paljudel juhtudel ei ole trombotsüütide agregatsiooni pärssivad ravimid, kaasa arvatud COX inhibiitor aspiriin, piisavalt efektiivsed trombitekke pidurdamisel.
Kobzar, Gennadi, Mardla, Vilja, Rätsep, Indrek, Samel, Nigulas   +3 more
core   +2 more sources

Multimodal Cross‐Attentive Graph‐Based Framework for Predicting In Vivo Endocrine Disruptors

Advanced Science, EarlyView.
A multimodal cross‐attentive graph neural network integrates molecular graphs with androgen and estrogen adverse outcome pathway (AOP)–anchored in vitro assay signals to predict in vivo endocrine disruption. By fusing information on Tier‐1 AOP logits with chemical structures, the framework achieves high accuracy and provides assay‐traceable ...
Eder Soares de Almeida Santos, Gustavo Felizardo Santos Sandes, Artur Christian Garcia da Silva, Holli‐Joi Martin, Eugene N. Muratov, Rodolpho de Campos Braga, Bruno Junior Neves   +6 more
wiley   +1 more source

Case report: Generalized bullous fixed drug eruption mimicking epidermal necrolysis

Frontiers in Medicine, 2023
Generalized bullous fixed drug eruption (GBFDE) is the most severe form of fixed drug eruption and can be misdiagnosed as epidermal necrolysis (EN). We report the case of a 42-year-old male patient presenting with more than 50% skin detachment without ...
Maren Paulmann, Felix Reinkemeier, Marcus Lehnhardt, Maja Mockenhaupt   +3 more
doaj   +1 more source

Pharmacological characteristics of metamizole

Polish Journal of Veterinary Sciences, 2014
Abstract Metamizole (dipyrone) is a popular analgetic, non-opioid drug, commonly used in human and veterinary medicine. In some cases, this agent is still incorrectly classified as a non-steroidal anti-inflammatory drug (NSAID). Metamizole is a pro-drug, which spontaneously breaks down after oral administration to structurally related pyrazolone ...
A, Jasiecka, T, Maślanka, J J, Jaroszewski   +2 more
openaire   +2 more sources

The quantitative impact of metabolism‐inhibiting drugs on the occurrence of adverse drug reactions—A backward selection approach

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The quantitative effect of several inhibitory drugs on the development of adverse drug reactions (ADRs) is currently difficult to estimate. Our aim was to identify metabolic pathways, which, when inhibited, increase the risk for certain ADRs, and to use this system to consider comedication at individual level. Methods Data of a prospective
Judith Berres, Justyna Wozniak, Hannah Fölsch, Anja Knueppel‐Ruppert, Verena Graeff, Andrea Kriegisch‐Stumpf, Harald Dormann, Julia C. Stingl, Katja S. Just   +8 more
wiley   +1 more source