Results 111 to 120 of about 877,036 (219)

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Correction: Osteopontin alters DNA methylation through up-regulating DNMT1 and sensitizes CD133+/CD44 + cancer stem cells to 5 azacytidine in hepatocellular carcinoma

Journal of Experimental & Clinical Cancer Research, 2023
Xiaomei Gao, Yuanyuan Sheng, Jing Yang, Chaoqun Wang, Rui Zhang, Ying Zhu, Ze Zhang, Kaili Zhang, Shican Yan, Haoting Sun, Jinwang Wei, Xuan Wang, Xinxin Yu, Yu Zhang, Qin Luo, Yan Zheng, Peng Qiao, Yue Zhao, Qiongzhu Dong, Lunxiu Qin   +19 more
doaj   +1 more source

Gastric metastasis from colorectal cancer: an updated comprehensive review of epidemiology, mechanisms, diagnosis, and management. [PDF]

Front Oncol
Wang C, Jie C, Su Y, Gu Z, Chen W.
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

NOL7 facilitates melanoma progression and metastasis

Signal Transduction and Targeted Therapy, 2021
Yumei Li, Chunlian Zhong, Jie Wang, Fan Chen, Weiyu Shen, Bifei Li, Ning Zheng, Yusheng Lu, Vladimir L. Katanaev, Lee Jia   +9 more
doaj   +1 more source

ZIP1-dependent lymphatic adaptations facilitate lymph node metastasis of pancreatic cancer. [PDF]

Int J Biol Sci
Chen R, Zhang K, Wan J, Yang Y, Wang L, Miao X, Fang Q, Hu Y, Duan X, Lou X, Yao X, Li A, Zhu L, Qin Z, Ni C.   +14 more
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Inguinal Lymph Node Metastasis from a Sigmoid Stomal Cancer: A Case Report. [PDF]

Surg Case Rep
Shirakawa K, Kobayashi H, Ishii T, Shibata K, Kuraoka N, Toyota K, Yano R, Hashimoto Y, Sakashita Y, Murakami Y, Miyamoto K.   +10 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Metastasis of Invasive Ductal Carcinoma of the Breast to the Uterine Cervix 30 Years Post-Mastectomy: A Case Report. [PDF]

J Obstet Gynaecol Res
Miyake T, Sasa H, Ito T, Watanabe T, Sato T, Ogata S, Takano M.   +6 more
europepmc   +1 more source