Results 61 to 70 of about 1,013,786 (315)

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Metastatic-initiating cells and lipid metabolism [PDF]

, 2017
The identity of the cells responsible for initiating and promoting metastasis has been historically elusive. Consequently, this has hampered our ability to develop specific anti-metastatic treatments, resulting in the majority of metastatic cancers ...
Salvador Aznar Benitah
core   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +21 more
wiley   +1 more source

The price of tumor control: an analysis of rare side effects of anti-CTLA-4 therapy in metastatic melanoma from the ipilimumab network [PDF]

, 2013
Background: Ipilimumab, a cytotoxic T-lymphocyte antigen-4 (CTLA-4) blocking antibody, has been approved for the treatment of metastatic melanoma and induces adverse events (AE) in up to 64% of patients.
Berking, Carola, Armin Justich (103646), Simone M. Goldinger, Daniela Göppner, Lucie M Heinzerling, Stephan Grabbe (103633), Clemens L. Bockmeyer, Robert Caroline, Thomas Eigentler, Christine Mateus (103663), Moos, Roger von, Loquai Carmen, Gerold Schuler, Dirk Schadendorf (103684), Christina Klein, Pätzold, Sylvie, Hundorfean, Gheorghe, Beatrice Schuler-Thurner, Göppner Daniela, Ralf Gutzmer (103628), Patrik Weder, Robert, Caroline, Bockmeyer, Clemens L., Dirk Schadendorf, Kaehler, Katharina C., Thomas Eigentler (103619), Katharina C. Kaehler, Gheorghe Hundorfean, Christine Mateus, Simone M. Goldinger (103594), Claus Garbe, Satzger, Imke, Ralf Gutzmer, Sylvie Paetzold (103676), Peter Mohr, Uwe Trefzer, Voskens, Caroline J, Carmen Loquai (103597), Bockmeyer Clemens L., Vaubel, Julia, Jens Ulrich, Wilhelm, Tabea, Bockmeyer, Clemens Luitpold, Julia Vaubel, Hauschild Axel, Mohr, Peter, Gheorghe Hundorfean (103642), Caroline J. Voskens, Justich, Armin, Hauschild, Axel, Fluck Michael, Loquai, Carmen, Schadendorf, Dirk, Beatrice Schuler-Thurner (103693), Satzger Imke, Göppner, Daniela, Carola Berking, Weder Patrik, Hundorfean Gheorghe, Eigentler, Thomas Kurt, Grabbe, Stephan, Ulrich Jens, Armin Justich, Rüdiger Hein (71354), Garbe Claus, Ulrich, Jens, Eigentler Thomas, Schadendorf Dirk, Gutzmer Ralf, Mateus Christine, Imke Satzger, Weder, Patrik, Ullrich Keller (103650), Lucie M. Heinzerling (103723), Gerold Schuler (103690), Axel Hauschild (103637), Christina Klein (103657), Michael Fluck, Tanja Bergmann (103612), Axel Hauschild, Paetzold Sylvie, Katharina C Kaehler, Wilhelm Tabea, Keller, Ullrich, Schlaeppi Marc, Goldinger, Simone M., Claus Garbe (48881), Berking Carola, Heinzerling, Lucie, von Moos Roger, Simone M Goldinger, Trefzer Uwe, Uwe Trefzer (72075), Rüdiger Hein, Mateus, Christine, Caroline Robert, Tabea Wilhelm (103712), Schuler Gerold, Dummer, Reinhard, Schuler-Thurner Beatrice, Roger von Moos, Hein Rüdiger, Eigentler, Thomas, Paetzold, Sylvie, Caroline J Voskens, Caroline J. Voskens (103590), Schuler-Thurner, Beatrice, Roger von Moos (103705), Patrik Weder (103709), Lucie M. Heinzerling, Kaehler, Katharina C, Voskens, Caroline J., Fluck, Michael, Imke Satzger (103681), Schuler, Gerold, Tanja Bergmann, Marc Schlaeppi (103687), Bergmann, Tanja Regina, Julia Vaubel (103700), Bergmann Tanja, Heinzerling, Lucie M., Stephan Grabbe, Klein Christina, Caroline Robert (103600), Carola Berking (103608), Kähler, Katharina C., Peter Mohr (103669), Klein, Christina, Tabea Wilhelm, Reinhard Dummer (103718), Goldinger Simone M., Reinhard Dummer, Marc Schlaeppi, Gutzmer, Ralf, Hein, Rüdiger, Clemens L Bockmeyer, Sylvie Paetzold, Michael Fluck (103622), Kaehler Katharina C., Justich Armin, Voskens Caroline J., Carmen Loquai, Vaubel Julia, Grabbe Stephan, Keller Ullrich, Mohr Peter, Jens Ulrich (103696), Trefzer, Uwe, Katharina C. Kaehler (103604), Bergmann, Tanja, Heinzerling Lucie M., Dummer Reinhard, et al, Goldinger, Simone M, Daniela Göppner (103715), Garbe, Claus, Clemens L. Bockmeyer (103616), Schlaeppi, Marc, Ullrich Keller   +158 more
core   +2 more sources

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Impact of the Specific Mutation in KRAS Codon 12 Mutated Tumors on Treatment Efficacy in Patients with Metastatic Colorectal Cancer Receiving Cetuximab-Based First-Line Therapy: A Pooled Analysis of Three Trials [PDF]

, 2012
Purpose: This study investigated the impact of specific mutations in codon 12 of the Kirsten-ras (KRAS) gene on treatment efficacy in patients with metastatic colorectal cancer (mCRC).
Zielinski, Christoph C., Neumann, Jens, Stintzing, Sebastian, Ocvirk, Janja, Heinemann, Volker, Kurteva, Galina, Jung, Andreas, Modest, Dominik P., Brodowicz, Thomas, Knittelfelder, Regina, Kirchner, Thomas, Papai, Zsuzsanna, Laubender, Ruediger P.   +12 more
core   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology
The increased metastatic ability of small‐cell lung cancer (SCLC) necessitates the identification of new prognostic biomarkers for clinical evaluation during the disease course.
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Cisplatin-based chemotherapy of testicular cancer - Two decades after a major breakthrough [PDF]

, 2000
Two decades ago the introduction of cisplatin-based combination chemotherapy has dramatically improved the prognosis of patients with metastatic testicular cancer, At present 3 cycles of cisplatin, etoposide and bleomycin are considered as standard ...
Gerl, Arthur
core   +1 more source