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2021
Breast cancer (BC) represents the most common malignancy among women worldwide. Metastatic BC (MBC) is currently considered an incurable disease; therefore, the main treatment objectives are improving quality of life and prolonging patient survival. Currently, three major therapeutic subtypes are considered for systemic treatment choice in MBC patients:
Giuseppe Buono +5 more
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Breast cancer (BC) represents the most common malignancy among women worldwide. Metastatic BC (MBC) is currently considered an incurable disease; therefore, the main treatment objectives are improving quality of life and prolonging patient survival. Currently, three major therapeutic subtypes are considered for systemic treatment choice in MBC patients:
Giuseppe Buono +5 more
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Current Opinion in ONCOLOGY, 1993
Tamoxifen as adjuvant systemic treatment after first isolated locoregional recurrence of breast cancer has been shown to decrease the subsequent locoregional relapse rate, but it affects neither distant metastases nor survival. In metastatic disease, tamoxifen has not improved response when added to ablation of ovarian function. The cyclical sequential
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Tamoxifen as adjuvant systemic treatment after first isolated locoregional recurrence of breast cancer has been shown to decrease the subsequent locoregional relapse rate, but it affects neither distant metastases nor survival. In metastatic disease, tamoxifen has not improved response when added to ablation of ovarian function. The cyclical sequential
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2012
The role of radiotherapy (RT) for metastatic breast cancer is broken down into three settings: the first and most common is palliative radiotherapy, the second is stereotactic RT for oligometastases instead of surgery, and the third is the irradiation of the breast for locoregional control.
Alanyalı S.D., Ozsaran Z.
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The role of radiotherapy (RT) for metastatic breast cancer is broken down into three settings: the first and most common is palliative radiotherapy, the second is stereotactic RT for oligometastases instead of surgery, and the third is the irradiation of the breast for locoregional control.
Alanyalı S.D., Ozsaran Z.
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Current Opinion in Oncology, 1996
The management of metastatic breast cancer continues to provide enormous challenges. The taxanes have significant activity in patients with resistant disease, and combination regimens are being evaluated as first-line therapy. The combination of paclitaxel and doxorubicin appears to have substantial activity, but troublesome cardiac toxicity has been ...
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The management of metastatic breast cancer continues to provide enormous challenges. The taxanes have significant activity in patients with resistant disease, and combination regimens are being evaluated as first-line therapy. The combination of paclitaxel and doxorubicin appears to have substantial activity, but troublesome cardiac toxicity has been ...
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CTCs in Metastatic Breast Cancer
2012Circulating tumor cells (CTCs), enumerated by the Food and Drugs Administration-cleared CellSearch(®) system, are an independent prognostic factor of progression-free survival (PFS) and overall survival (OS) in metastatic breast cancer (MBC) patients.
Massimo Cristofanilli +2 more
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2019
De novo Stage IV breast cancer compromises 5–6% of woman with breast cancer. Systemic staging at the time of initial presentation is recommended for patients with clinical Stage IIIA disease or patients who have symptoms concerning for metastatic disease. Patients were suspected to have metastatic disease should be referred to medical oncology.
Laura Kruper, Zeynep Bostanci
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De novo Stage IV breast cancer compromises 5–6% of woman with breast cancer. Systemic staging at the time of initial presentation is recommended for patients with clinical Stage IIIA disease or patients who have symptoms concerning for metastatic disease. Patients were suspected to have metastatic disease should be referred to medical oncology.
Laura Kruper, Zeynep Bostanci
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Ovarian cancer metastatic to the breast
Gynecologic Oncology, 2006Metastatic ovarian cancer to the breast should be considered in the differential diagnosis for gynecologic cancer patients with a breast tumor. Despite early detection and treatment, the long-term prognosis for these patients is poor.We present three ovarian cancer patients who developed metastatic ovarian cancer to the breast.
John V. Brown +4 more
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Curing Metastatic Breast Cancer [PDF]
Journal of Oncology Practice, 2016 Metastatic breast cancer is generally considered incurable, and this colors doctor-patient interactions for patients with metastatic disease. Although true for most patients, there appear to be important exceptions, instances where long-term disease-free survival occurs. Although these instances are few in number, they suggest the possibility of cure.
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Management of metastatic breast cancer
World Journal of Surgery, 1994AbstractSystemic treatment almost certainly prolongs the median survival of women with metastatic breast cancer, and it may prolong the survival of a small number of patients substantially. Even with conventional therapy, 10% or more patients may live into the second decade after recurrence.
K Wong, I C Henderson
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2010
Metastatic breast cancer is a leading cause of morbidity and mortality that needs to be understood and conquered. Although fewer than 10% of patients with breast cancer initially present with the metastatic disease, it will eventually develop in a substantial proportion of them [1]. Therapy for metastatic breast cancer remains palliative.
Tejal Patel, Edith A. Perez
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Metastatic breast cancer is a leading cause of morbidity and mortality that needs to be understood and conquered. Although fewer than 10% of patients with breast cancer initially present with the metastatic disease, it will eventually develop in a substantial proportion of them [1]. Therapy for metastatic breast cancer remains palliative.
Tejal Patel, Edith A. Perez
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